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Lab Diagnosis of Microorganisms

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Questions and Answers

What is the causative agent of syphilis?

Treponema pallidum

What is the primary method of direct diagnosis for syphilis?

Darkfield microscopic identification of bacteria

What is the purpose of the FTA-ABS test in syphilis diagnosis?

To detect anti-treponemal antibodies

What is the difference between VDRL and RPR tests in syphilis diagnosis?

RPR test uses lecithin bound to support, whereas VDRL test does not. Signup and view all the answers

What is the role of cardiolipin in syphilis diagnosis?

It acts as an antigen to detect reagin-type antibodies Signup and view all the answers

What is the purpose of the TPHA test in syphilis diagnosis?

To detect and measure antibodies against Treponema pallidum Signup and view all the answers

How does the ELISA test work in syphilis diagnosis?

It detects reagin-type antibodies by binding to cardiolipin bound to a plate Signup and view all the answers

What is the significance of indirect diagnosis in syphilis?

It detects antibodies against Treponema pallidum in the serum of a patient Signup and view all the answers

What is the role of fluorescent-labeled, monoclonal antibodies in syphilis diagnosis?

They are used to detect Treponema pallidum in the darkfield microscopic identification Signup and view all the answers

What is the significance of chronic abdominal pain in syphilis?

It can be a symptom of syphilis, especially in advanced stages Signup and view all the answers