Podcast
Questions and Answers
What occurs after action potential is propagated along the sarcolemma?
What occurs after action potential is propagated along the sarcolemma?
- Muscle lengthen without changing tension
- Troponin binds to tropomyosin
- Cross bridges form and contraction begins (correct)
- Acetylcholine is released into the muscle
Which structure releases Ca2+ into the cytosol during excitation-contraction coupling?
Which structure releases Ca2+ into the cytosol during excitation-contraction coupling?
- Troponin
- Sarcoplasmic reticulum (correct)
- T-tubules
- Sarcolemma
Which of the following describes an isometric contraction?
Which of the following describes an isometric contraction?
- Muscle length does not change during contraction (correct)
- Muscle shortens while doing work
- Muscle changes in length but maintains the same tension
- Muscle lengthens while doing work
What initiates the process of exposing myosin-binding sites on thin filaments?
What initiates the process of exposing myosin-binding sites on thin filaments?
Which of the following best defines concentric contractions?
Which of the following best defines concentric contractions?
What is the connective tissue sheath that surrounds the entire muscle?
What is the connective tissue sheath that surrounds the entire muscle?
Which structure is the smallest contractile unit of a muscle?
Which structure is the smallest contractile unit of a muscle?
Which connective tissue surrounds each individual muscle fiber?
Which connective tissue surrounds each individual muscle fiber?
What type of filament contains actin or myosin?
What type of filament contains actin or myosin?
At the neuromuscular junction, what enters the motor neuron after the voltage-gated channels open?
At the neuromuscular junction, what enters the motor neuron after the voltage-gated channels open?
Which part of the muscle structure is responsible for attaching muscle to bone?
Which part of the muscle structure is responsible for attaching muscle to bone?
What is the role of acetylcholine at the neuromuscular junction?
What is the role of acetylcholine at the neuromuscular junction?
What change occurs in the membrane potential during the end plate potential?
What change occurs in the membrane potential during the end plate potential?
Flashcards
Endomysium
Endomysium
Connective tissue surrounding each muscle fiber.
Perimysium
Perimysium
Connective tissue surrounding a fascicle (bundle) of muscle fibers.
Epimysium
Epimysium
Connective tissue sheath surrounding the entire muscle.
Muscle Fiber
Muscle Fiber
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Fascicle
Fascicle
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Myofibril
Myofibril
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Sarcomere
Sarcomere
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Myofilament
Myofilament
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Sarcolemma
Sarcolemma
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Tendon
Tendon
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Neuromuscular Junction
Neuromuscular Junction
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Motor neuron
Motor neuron
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Action Potential
Action Potential
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Synaptic Vesicles
Synaptic Vesicles
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Neurotransmitters
Neurotransmitters
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Acetylcholine (ACh)
Acetylcholine (ACh)
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Action Potential Propagation
Action Potential Propagation
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Neurotransmitter Removal
Neurotransmitter Removal
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Excitation-Contraction Coupling Steps
Excitation-Contraction Coupling Steps
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Isometric Contraction
Isometric Contraction
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Isotonic Contraction
Isotonic Contraction
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Concentric Contraction
Concentric Contraction
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Eccentric Contraction
Eccentric Contraction
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Sarcomere Length/Stage
Sarcomere Length/Stage
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Study Notes
Lab 7: Muscles and Muscle Tissue
- Submitting Answers: Submit answers to the untimed quiz on Blackboard. Work through the quiz beforehand, writing answers on paper or a document. Afterward, open the online quiz to fill it out and submit.
- Muscle Structure:
- Connective Tissue Surrounding Bundle: Epimysium
- Bundle of Muscle Fibers: Fascicle
- Smallest Contractile Unit: Myofibril
- Connective Tissue Around Entire Muscle: Perimysium
- Connective Tissue Surrounding Each Muscle Fiber: Endomysium
- Plasma Membrane of Muscle Fiber: Sarcolemma
- Organelle in Muscle Fiber: Sarcomere
- Actin or Myosin Structure: Myofilament
- Collagen Fiber Attaching Muscle to Bone: Tendon
- Muscle Fiber Components:
- I band: (light band)
- A band: (dark band)
- Z disc:
- H zone:
- M line:
- Sarcolemma:
- Triad (tubules of SR)
- Myofibrils:
- Mitochondria:
- Thin Filament Components:
- Actin Subunits:
- Portion of Thin Filament
- Troponin and Tropomyosin: (regulatory proteins)
- Thick Filament Components:
- Myosin Molecules:
- Portion of Thick Filament
- Heads:
- Flexible Hinge Region:
- Neuromuscular Junction:
- Motor Neuron:
- ACh: (neurotransmitter)
- Cytoplasm of Skeletal Muscle Fiber:
- Sarcolemma:
- Excitation-Contraction Coupling:
- Action Potential (AP): arrives at axon terminal, enters motor neuron, opens voltage-gated channels, causes calcium release, diffuses, binds to ACh receptors, etc.
- Neurotransmitter (ACh): Released into synaptic cleft, binds to receptors; resulting in membrane potential shifts to become negative (end-plate potential).
- Muscle Twitch (Isometric):
- Phases: Three phases visible on a myogram (graph).
- Isometric Contraction : muscle length stays the same.
- Concentric Contraction: Muscle shortens while doing work
- Eccentric Contraction: Muscle lengthens while doing work.
- Sarcomere Length:
- Optimal Sarcomere Length: 80%-120% of resting length, optimal for tension and force generation.
- Changes in Sarcomere Length affect tension generation.
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