Podcast
Questions and Answers
cells actively control the composition of their immediate environment and intracellular milieu within a narrow range of physiological parameters
cells actively control the composition of their immediate environment and intracellular milieu within a narrow range of physiological parameters
homeostatis
denotes pathologic changes that can be reversed when the stimulus is removed, or if the cause of injury is mild
denotes pathologic changes that can be reversed when the stimulus is removed, or if the cause of injury is mild
reversible cell injury
it is under physiological stresses or pathological stimuli
it is under physiological stresses or pathological stimuli
injury
denotes pathologic changes that are permanent and cause cell death
denotes pathologic changes that are permanent and cause cell death
three hypoxic cell injury
three hypoxic cell injury
high susceptibility of cells to hypoxic injury
high susceptibility of cells to hypoxic injury
intermediate susceptibility of cells to hypoxic injury
intermediate susceptibility of cells to hypoxic injury
low susceptibility of cells to hypoxic injury
low susceptibility of cells to hypoxic injury
three free radical induced injury
three free radical induced injury
double bonds in polyunsaturated membrane lipids are vulnerable to attack by oxygen free radicals
double bonds in polyunsaturated membrane lipids are vulnerable to attack by oxygen free radicals
free radicals promote sulfhydryl-mediated protein cross linking, resulting in increased degradation and loss of activity
free radicals promote sulfhydryl-mediated protein cross linking, resulting in increased degradation and loss of activity
free radicals react with thymine in nuclear and mitochondrial
free radicals react with thymine in nuclear and mitochondrial
neutralizations of free radicals
neutralizations of free radicals
trauma, heat, cold, radiation, electric shock that causes cellular injury
trauma, heat, cold, radiation, electric shock that causes cellular injury
a oxygen deprivation that causes cellular injury
a oxygen deprivation that causes cellular injury
a chemical species with a single unpaired electron in an outer orbital that causes cellular injury; ROS – Hydroxyl, Hydrogen, Superoxide
a chemical species with a single unpaired electron in an outer orbital that causes cellular injury; ROS – Hydroxyl, Hydrogen, Superoxide
9 causes of cellular injury
9 causes of cellular injury
a vitamin deficiencies, obesity leading to type II DM, fat leading to atherosclerosis that causes cellular injuey
a vitamin deficiencies, obesity leading to type II DM, fat leading to atherosclerosis that causes cellular injuey
a anaphylaxis, loss of immune tolerance leading to autoimmunity that causes cellular injury
a anaphylaxis, loss of immune tolerance leading to autoimmunity that causes cellular injury
a degeneration as a result of trauma, intrinsic cellular senesence that causes cellular injury
a degeneration as a result of trauma, intrinsic cellular senesence that causes cellular injury
a sickle cell disease, inborn errors of metabolism that causes cellular injury
a sickle cell disease, inborn errors of metabolism that causes cellular injury
a direct effects of bacterial toxins that causes cellular injury
a direct effects of bacterial toxins that causes cellular injury
diff. infectious agents
diff. infectious agents
diff. chemical agents
diff. chemical agents
