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Questions and Answers
What is the rate of oxygen consumption reported for odontoblasts in the pulp tissue?
What is the rate of oxygen consumption reported for odontoblasts in the pulp tissue?
- 3.2 +- 0.1 mL/min/100 g of pulp
- 3.2 +- 0.2 mL/min/100 g of pulp (correct)
- 2.8 +- 0.3 mL/min/100 g of pulp
- 3.5 +- 0.2 mL/min/100 g of pulp
Which region of the pulp exhibits the lowest metabolic activity?
Which region of the pulp exhibits the lowest metabolic activity?
- Odontoblast layer
- Dentin region
- Periphery of the pulp
- Central pulp (correct)
⭐️How does the pulp tissue manage to survive periods of low perfusion?
⭐️How does the pulp tissue manage to survive periods of low perfusion?
- Phosphogluconate shunt metabolism (correct)
- Higher cellular density
- Increased glycolytic activity
- Enhanced oxygen uptake
What impact do certain dental materials have on the pulp's metabolism?
What impact do certain dental materials have on the pulp's metabolism?
What was the approximate percentage reduction in respiratory activity observed after orthodontic force was applied to premolars?
What was the approximate percentage reduction in respiratory activity observed after orthodontic force was applied to premolars?
What technique was used to quantify CO2 production during the study involving succinic acid?
What technique was used to quantify CO2 production during the study involving succinic acid?
Which metabolic pathway does the pulp utilize during periods of low blood flow?
Which metabolic pathway does the pulp utilize during periods of low blood flow?
Which statement best characterizes the metabolic activity of pulp tissue?
Which statement best characterizes the metabolic activity of pulp tissue?
What is the main characteristic of the pulp's cellular composition?
What is the main characteristic of the pulp's cellular composition?
Which of the following is NOT a dental material known to inhibit oxygen consumption in pulp tissue?
Which of the following is NOT a dental material known to inhibit oxygen consumption in pulp tissue?
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Study Notes
Pulp Metabolism
- Pulp metabolic activity is measured by oxygen consumption, CO2 production, and lactic acid production.
- Odontoblasts consume oxygen at a rate of 3.2 ± 0.2 mL/min/100 g of pulp tissue.
- Pulp has a relatively low rate of oxygen consumption compared to other tissues due to its sparse cellular composition.
- Pulp metabolic activity is higher during active dentinogenesis than after crown completion.
- The highest metabolic activity is found in the odontoblast layer, while the lowest is in the central pulp, where nerves and blood vessels are concentrated.
- Pulp utilizes both glycolysis and the pentose phosphate shunt for energy production, allowing it to function under ischemic conditions.
- This explains how pulp withstands periods of low blood flow during epinephrine-containing anesthesia.
- Dental materials like eugenol, zinc oxide and eugenol, calcium hydroxide, and silver amalgam inhibit pulp oxygen consumption, potentially depressing pulpal cell activity.
- Applying orthodontic force to premolars for 3 days can reduce pulp respiratory activity by 27%.
- Carbon-14-labeled succinic acid is used to quantify CO2 production during pulp metabolism, requiring only a few milligrams of tissue.
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