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Questions and Answers
What is the rate of oxygen consumption reported for odontoblasts in the pulp tissue?
Which region of the pulp exhibits the lowest metabolic activity?
⭐️How does the pulp tissue manage to survive periods of low perfusion?
What impact do certain dental materials have on the pulp's metabolism?
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What was the approximate percentage reduction in respiratory activity observed after orthodontic force was applied to premolars?
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What technique was used to quantify CO2 production during the study involving succinic acid?
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Which metabolic pathway does the pulp utilize during periods of low blood flow?
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Which statement best characterizes the metabolic activity of pulp tissue?
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What is the main characteristic of the pulp's cellular composition?
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Which of the following is NOT a dental material known to inhibit oxygen consumption in pulp tissue?
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Study Notes
Pulp Metabolism
- Pulp metabolic activity is measured by oxygen consumption, CO2 production, and lactic acid production.
- Odontoblasts consume oxygen at a rate of 3.2 ± 0.2 mL/min/100 g of pulp tissue.
- Pulp has a relatively low rate of oxygen consumption compared to other tissues due to its sparse cellular composition.
- Pulp metabolic activity is higher during active dentinogenesis than after crown completion.
- The highest metabolic activity is found in the odontoblast layer, while the lowest is in the central pulp, where nerves and blood vessels are concentrated.
- Pulp utilizes both glycolysis and the pentose phosphate shunt for energy production, allowing it to function under ischemic conditions.
- This explains how pulp withstands periods of low blood flow during epinephrine-containing anesthesia.
- Dental materials like eugenol, zinc oxide and eugenol, calcium hydroxide, and silver amalgam inhibit pulp oxygen consumption, potentially depressing pulpal cell activity.
- Applying orthodontic force to premolars for 3 days can reduce pulp respiratory activity by 27%.
- Carbon-14-labeled succinic acid is used to quantify CO2 production during pulp metabolism, requiring only a few milligrams of tissue.
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