Local control of Blood Flow and Resistance Vasculature Quiz

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Questions and Answers

Which molecule is responsible for the relaxation of blood vessels in response to shear stress?

  • cGMP
  • Endothelin
  • cGTP
  • NO (correct)

What is the main action of cGMP-dependent protein kinase?

  • Formation of blood clots
  • Relaxation of blood vessels (correct)
  • Vasoconstriction
  • Increase in blood flow

Which substance is released from damaged endothelium and acts as a powerful vasoconstrictor?

  • Endothelin (correct)
  • NO
  • cGMP
  • cGTP

What happens to vascularity when the metabolism in a tissue is increased for a prolonged period?

<p>Angiogenesis occurs (B)</p> Signup and view all the answers

What is the main mechanism for long-term local blood flow regulation?

<p>Changes in tissue vascularity (A)</p> Signup and view all the answers

What is the term for the increase in vascularity of trained muscles in response to chronic exercise training?

<p>Angiogenesis (A)</p> Signup and view all the answers

What is the main effect of inward eutrophic remodeling?

<p>Decrease in the lumen diameter (B)</p> Signup and view all the answers

What is the main effect of hypertrophic remodeling in larger arteries?

<p>Increase in the cross-sectional area of the vascular wall (A)</p> Signup and view all the answers

Which of the following is NOT a specific need for local control of blood flow in tissues?

<p>Delivery of glucose to tissues (A)</p> Signup and view all the answers

What are the two phases of local blood flow control?

<p>Acute and chronic (B)</p> Signup and view all the answers

What is the main action of endothelin released from damaged endothelium?

<p>Vasoconstriction (C)</p> Signup and view all the answers

What is the main action of NO in vascular smooth muscle cells?

<p>Relaxation of blood vessels (C)</p> Signup and view all the answers

Which blood vessels are involved in the acute control of blood flow?

<p>Arterioles, metarterioles, and precapillary sphincters (A)</p> Signup and view all the answers

What happens to blood flow in a local tissue when the rate of metabolism increases up to 8 times normal?

<p>It increases by fourfold (B)</p> Signup and view all the answers

Which condition can cause an increase in tissue blood flow due to reduced oxygen availability?

<p>High altitudes (B)</p> Signup and view all the answers

What does the second figure in the text show?

<p>The effect of reduced arterial oxygen saturation on blood flow (B)</p> Signup and view all the answers

What is the main characteristic of long-term control of blood flow?

<p>Slow, controlled changes over a period of days, weeks, or months (B)</p> Signup and view all the answers

Which of the following is NOT a condition that can cause an increase in tissue blood flow due to reduced oxygen availability?

<p>Asthma (D)</p> Signup and view all the answers

What is the approximate effect on blood flow when the arterial oxygen saturation decreases to about 25% of normal?

<p>It increases by threefold (A)</p> Signup and view all the answers

How long does the chronic phase of local blood flow control typically last?

<p>Weeks to months (B)</p> Signup and view all the answers

Which of the following substances is NOT suggested as a vasodilator in the vasodilator theory for acute local blood flow regulation?

<p>Oxygen (C)</p> Signup and view all the answers

What is the name of the theory that suggests that blood vessels dilate in the absence of adequate oxygen?

<p>Oxygen Demand Theory (D)</p> Signup and view all the answers

What is the term used to describe the cyclical opening and closing of precapillary sphincters and metarterioles?

<p>Vasomotion (B)</p> Signup and view all the answers

What is the term for the increase in blood flow through a tissue that occurs when the blood supply is blocked and then unblocked?

<p>Reactive hyperemia (B)</p> Signup and view all the answers

What is the primary factor that mediates myogenic regulation of tissue blood flow?

<p>Stretch-activated calcium channels (A)</p> Signup and view all the answers

Which of the following is NOT a role of endothelial cells in the control of tissue blood flow?

<p>Regulating neural influence (A)</p> Signup and view all the answers

What is the half-life of nitric oxide in the blood?

<p>6 seconds (D)</p> Signup and view all the answers

What is the name for the enzyme responsible for synthesizing nitric oxide from arginine and oxygen?

<p>eNOS (C)</p> Signup and view all the answers

What is the term used to describe the immediate rise in blood flow that occurs in most tissues when arterial pressure is rapidly increased?

<p>Auto regulation (C)</p> Signup and view all the answers

What is the role of vasodilator substances in the vasodilator theory for acute local blood flow regulation?

<p>They cause dilation of blood vessels (D)</p> Signup and view all the answers

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