Local control of Blood Flow and Resistance Vasculature Quiz
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Questions and Answers

Which molecule is responsible for the relaxation of blood vessels in response to shear stress?

  • cGMP
  • Endothelin
  • cGTP
  • NO (correct)
  • What is the main action of cGMP-dependent protein kinase?

  • Formation of blood clots
  • Relaxation of blood vessels (correct)
  • Vasoconstriction
  • Increase in blood flow
  • Which substance is released from damaged endothelium and acts as a powerful vasoconstrictor?

  • Endothelin (correct)
  • NO
  • cGMP
  • cGTP
  • What happens to vascularity when the metabolism in a tissue is increased for a prolonged period?

    <p>Angiogenesis occurs</p> Signup and view all the answers

    What is the main mechanism for long-term local blood flow regulation?

    <p>Changes in tissue vascularity</p> Signup and view all the answers

    What is the term for the increase in vascularity of trained muscles in response to chronic exercise training?

    <p>Angiogenesis</p> Signup and view all the answers

    What is the main effect of inward eutrophic remodeling?

    <p>Decrease in the lumen diameter</p> Signup and view all the answers

    What is the main effect of hypertrophic remodeling in larger arteries?

    <p>Increase in the cross-sectional area of the vascular wall</p> Signup and view all the answers

    Which of the following is NOT a specific need for local control of blood flow in tissues?

    <p>Delivery of glucose to tissues</p> Signup and view all the answers

    What are the two phases of local blood flow control?

    <p>Acute and chronic</p> Signup and view all the answers

    What is the main action of endothelin released from damaged endothelium?

    <p>Vasoconstriction</p> Signup and view all the answers

    What is the main action of NO in vascular smooth muscle cells?

    <p>Relaxation of blood vessels</p> Signup and view all the answers

    Which blood vessels are involved in the acute control of blood flow?

    <p>Arterioles, metarterioles, and precapillary sphincters</p> Signup and view all the answers

    What happens to blood flow in a local tissue when the rate of metabolism increases up to 8 times normal?

    <p>It increases by fourfold</p> Signup and view all the answers

    Which condition can cause an increase in tissue blood flow due to reduced oxygen availability?

    <p>High altitudes</p> Signup and view all the answers

    What does the second figure in the text show?

    <p>The effect of reduced arterial oxygen saturation on blood flow</p> Signup and view all the answers

    What is the main characteristic of long-term control of blood flow?

    <p>Slow, controlled changes over a period of days, weeks, or months</p> Signup and view all the answers

    Which of the following is NOT a condition that can cause an increase in tissue blood flow due to reduced oxygen availability?

    <p>Asthma</p> Signup and view all the answers

    What is the approximate effect on blood flow when the arterial oxygen saturation decreases to about 25% of normal?

    <p>It increases by threefold</p> Signup and view all the answers

    How long does the chronic phase of local blood flow control typically last?

    <p>Weeks to months</p> Signup and view all the answers

    Which of the following substances is NOT suggested as a vasodilator in the vasodilator theory for acute local blood flow regulation?

    <p>Oxygen</p> Signup and view all the answers

    What is the name of the theory that suggests that blood vessels dilate in the absence of adequate oxygen?

    <p>Oxygen Demand Theory</p> Signup and view all the answers

    What is the term used to describe the cyclical opening and closing of precapillary sphincters and metarterioles?

    <p>Vasomotion</p> Signup and view all the answers

    What is the term for the increase in blood flow through a tissue that occurs when the blood supply is blocked and then unblocked?

    <p>Reactive hyperemia</p> Signup and view all the answers

    What is the primary factor that mediates myogenic regulation of tissue blood flow?

    <p>Stretch-activated calcium channels</p> Signup and view all the answers

    Which of the following is NOT a role of endothelial cells in the control of tissue blood flow?

    <p>Regulating neural influence</p> Signup and view all the answers

    What is the half-life of nitric oxide in the blood?

    <p>6 seconds</p> Signup and view all the answers

    What is the name for the enzyme responsible for synthesizing nitric oxide from arginine and oxygen?

    <p>eNOS</p> Signup and view all the answers

    What is the term used to describe the immediate rise in blood flow that occurs in most tissues when arterial pressure is rapidly increased?

    <p>Auto regulation</p> Signup and view all the answers

    What is the role of vasodilator substances in the vasodilator theory for acute local blood flow regulation?

    <p>They cause dilation of blood vessels</p> Signup and view all the answers

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