quiz 5 Koch's Molecular Postulates Quiz micro 1,2 renal
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Questions and Answers

What is the main purpose of microbial identification?

  • To identify the source of infection
  • To determine the antimicrobial susceptibility of microbes
  • To distinguish between different species of microbes (correct)
  • To link lecture content with laboratory work
  • Which method is used for increasing the accuracy of identifying microorganisms based on colony morphology?

  • Electron microscopy
  • Sub-culturing individual colonies (correct)
  • Immunologic analysis
  • Gram's staining
  • What is NOT a part of diagnostic microbiology?

  • Molecular biology (correct)
  • Pharmaceutical microbiology
  • Veterinary microbiology
  • Plant (crop) pathology
  • Which technique is commonly used for microbial identification?

    <p>Colony morphology</p> Signup and view all the answers

    What type of media is used for selective growth of specific microbes?

    <p>MacConkey agar</p> Signup and view all the answers

    What is the primary purpose of identifying microbial contaminants?

    <p>To characterize contaminants in pharmaceuticals</p> Signup and view all the answers

    Which type of agar is selective for certain fungi, with low pH and high glucose?

    <p>Sabouraud Dextrose Agar</p> Signup and view all the answers

    What is the main purpose of Mannitol Salt Agar?

    <p>Differentiates Staphylococci based on Mannitol and phenol red</p> Signup and view all the answers

    Which microscopy technique involves staining and can identify pure bacterial cultures using Gram staining?

    <p>Light microscopy</p> Signup and view all the answers

    What is the main purpose of API strips in biochemical profiling?

    <p>Obtaining numerical codes for organisms</p> Signup and view all the answers

    Which method is increasingly used for identification due to its speed and cost, and is based on ionized molecules?

    <p>MALDI TOF</p> Signup and view all the answers

    What are the ideal qualities of a diagnostic method as mentioned in the text?

    <p>Specific, rapid, inexpensive, accurate</p> Signup and view all the answers

    Which of the following is NOT an example of a waterborne disease?

    <p>Salmonella</p> Signup and view all the answers

    What is the term for the relative degree of damage done by a pathogen?

    <p>Virulence</p> Signup and view all the answers

    Which of the following is an example of an obligate pathogen?

    <p>Mycobacterium tuberculosis</p> Signup and view all the answers

    What is the term for an intracellular pathogen's ability to obtain nutrition from the host?

    <p>Colonization of a niche in the host</p> Signup and view all the answers

    Which term refers to an infection present in a population which is maintained constantly with no external input?

    <p>Endemic</p> Signup and view all the answers

    What is the main source of highly infectious diseases such as HIV and smallpox?

    <p>People</p> Signup and view all the answers

    Which term refers to a microorganism that normally resides on the body without causing disease but can cause disease when the microbial balance is upset?

    <p>Opportunistic pathogen</p> Signup and view all the answers

    Which of the following is NOT a major source of zoonotic infectious diseases?

    <p>Fungi</p> Signup and view all the answers

    What is the term for the combination of two or more different strains of a virus producing a new form of virus?

    <p>Antigenic shift</p> Signup and view all the answers

    Which occupation does NOT traditionally come in close contact with animals or animal products?

    <p>Laboratory technician</p> Signup and view all the answers

    What is the main risk factor for exposure to zoonotic infectious diseases?

    <p>Close contact with infected animals or contaminated environments</p> Signup and view all the answers

    What is the term for accumulation of mutations within antibody binding regions that reduces the effectiveness of the immune system?

    <p>Antigenic drift</p> Signup and view all the answers

    What is the term for the groups of microorganisms that stick to each other and surfaces, playing a significant role in the pathogenesis of many infections?

    <p>Biofilms</p> Signup and view all the answers

    Which of the following can lead to septic shock and is part of the bacterial cell membrane?

    <p>Endotoxins (LPS)</p> Signup and view all the answers

    What is the term for the ability of pathogens to resist host responses and obtain appropriate nutrients?

    <p>Virulence</p> Signup and view all the answers

    What can initially cause fever and shock due to the release of endotoxins?

    <p>Antibiotics</p> Signup and view all the answers

    Who can cause red blood cell lysis and can be proteins or lipid biosurfactants?

    <p>Haemolysins</p> Signup and view all the answers

    Which type of bacteria are classified based on their staining properties and can affect their response to antibiotics?

    <p>Gram-positive</p> Signup and view all the answers

    Which route of disease transmission involves transmission through other organisms?

    <p>Vector borne (through other organisms)</p> Signup and view all the answers

    What is the term for the ability of bacteria to attach to host cells using pili or adhesins and resist phagocytosis with capsules?

    <p>Virulence</p> Signup and view all the answers

    What is the term for the process that can lead to haemolytic anemia and is caused by bacteria's hemolytic activity?

    <p>Hemolysis</p> Signup and view all the answers

    What depends on multiple factors including microbe count, environmental persistence, and route of transmission?

    <p>Disease exposure</p> Signup and view all the answers

    'Vehicle borne' disease transmission occurs through which medium?

    <p>Inanimate objects</p> Signup and view all the answers

    The role of biofilms in infections can increase a patient's average hospital stay and resistance to treatment by what percentage?

    <p>80%</p> Signup and view all the answers

    Which of the following hormones is a potent vasoconstrictor of both afferent and efferent arterioles, thus reducing glomerular filtration rate (GFR)?

    <p>Angiotensin II</p> Signup and view all the answers

    What hormone causes the glomerulus to relax, increasing the surface area for filtration?

    <p>Atrial natriuretic peptide (ANP)</p> Signup and view all the answers

    Which hormone is released in response to low blood flow and affects facultative water reabsorption by increasing the water permeability of principal cells in the last part of the distal convoluted tubule and throughout the collecting duct?

    <p>Antidiuretic hormone (ADH)</p> Signup and view all the answers

    Which hormone is released by the parathyroid gland and stimulates cells in the early distal convoluted tubule to reabsorb Ca2+ into the blood?

    <p>Parathyroid hormone (PTH)</p> Signup and view all the answers

    Which part of the brain is responsible for triggering the release of antidiuretic hormone (ADH) in response to low blood flow?

    <p>Hypothalamus</p> Signup and view all the answers

    Which of the following ions is reabsorbed in the proximal convoluted tubule, promoted by parathyroid hormone (PTH)?

    <p>Phosphate ions</p> Signup and view all the answers

    What percentage of filtered water is reabsorbed in the thick ascending limb of the loop of Henle?

    <p>15%</p> Signup and view all the answers

    Which fungal disease is caused by Candida albicans and leads to white patches in the mouth or genitals?

    <p>Thrush</p> Signup and view all the answers

    What is the common fungal disease causing irritation, dry and inflamed skin with localised pain?

    <p>Athlete's foot</p> Signup and view all the answers

    Which fungal disease is commonly caused by Aspergillus fumigatus and can be invasive in immune-compromised patients?

    <p>Aspergillosis</p> Signup and view all the answers

    Which viral disease can lead to cervical cancer?

    <p>HPV</p> Signup and view all the answers

    Which virus can lead to human breast cancer?

    <p>Mouse mammary tumor virus</p> Signup and view all the answers

    Where are the kidneys located in the body?

    <p>Below the diaphragm and adjacent to the vertebral column</p> Signup and view all the answers

    Which organ is located below the diaphragm and adjacent to the vertebral column, causing the right kidney to be lower?

    <p>Liver</p> Signup and view all the answers

    What is the function of kidneys?

    <p>Regulating blood volume, chemical composition, and pH</p> Signup and view all the answers

    Study Notes

    • Mycoses are fungal diseases that can be persistent, localised or systemic, often caused by inhalation of fungal spores, and common in immunocompromised patients or those who have taken antibiotics
    • Athlete's foot is a common fungal disease causing irritation, dry and inflamed skin with localised pain, caused by species of Trichophyton, Epidermophyton, and Microsporum
    • Thrush is another fungal disease caused by Candida albicans, leading to white patches in the mouth or genitals
    • Aspergillosis is a fungal disease commonly caused by Aspergillus fumigatus and can be invasive in immune-compromised patients
    • Viral diseases can cause both communicable and non-communicable diseases, with examples including Herpes, HIV, Influenza, HPV leading to cervical cancer, Human adenovirus leading to obesity, and Mouse mammary tumor virus leading to human breast cancer
    • Urinary system consists of paired, bean-shaped organs located along the back body wall below the diaphragm and adjacent to the vertebral column, with the right kidney being lower due to liver occupying more space on the right side
    • Each kidney receives around 1/4 of cardiac output and is supplied by the renal arteries, with similar paths for arterial flow in and venous flow out, and the nerve supply being via sympathetic fibers from the renal plexus
    • Kidneys perform functions of removing toxins, metabolic wastes, and excess ions from the blood, regulating blood volume, chemical composition, and pH, and endocrine functions including gluconeogenesis during prolonged fasting, renin regulation of blood pressure and kidney function, and erythropoietin regulation of RBC production
    • A nephron is a structural and functional unit of the kidney that forms urine, with each kidney having around 1 million nephrons, and cortical nephrons making up about 80-85% of the total having short loops of Henle and receiving blood supply from peritubular capillaries, and juxtamedullary nephrons making up the remaining 15-20% having long loops of Henle and receiving blood supply from the vasa recta
    • Collecting ducts of several nephrons empty into a single collecting duct, which unites and converges into several hundred large papillary ducts that drain into the minor calyces, major calyces, renal pelvis, and ureters
    • Renal corpuscle, the initial filtering component of a nephron, consists of a glomerulus and a Bowman's capsule
    • Glomerular filtration is the process by which the kidney filters blood to form filtrate, with about half being returned to the blood and the other half becoming urine
    • Filtrate contains around 3L of water, 200g of protein, and small amounts of glucose, urea, and creatinine, with most being reabsorbed back into the blood and the remaining being excreted in the urine.

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