30 Questions
What is the term for the early stage of the parasite's growth inside the erythrocyte?
Trophozoite
What is the result of the multiple rounds of nuclear division without cytokinesis in the trophic period?
Schizont
What is the primary function of the trophozoite during its growth inside the erythrocyte?
Ingesting host cytoplasm
Which of the following is NOT a stage in the blood-stage replicative cycle of the malaria parasite?
Meiosis
What percentage of malaria cases are attributed to Plasmodium falciparum?
50%
What is the estimated number of children under five who die from malaria every day in Africa?
3000
What is the form of the parasite that invades erythrocytes?
Merozoite
Which stage of the parasite undergoes exflagellation to form gametes?
Microgametocyte
What is the result of the schizogony process in the hepatocyte?
Formation of merozoites
In which stage of the parasite's life cycle does mitosis occur?
Oocyst
What is the term for the life cycle of the parasite in the vertebrate host?
Erythrocytic cycle
What is the result of the fusion of ingested gametes in the mosquito gut?
Formation of zygote
What is the advantage of having sickle cell trait in relation to falciparum malaria?
Reduced risk of acute illness
What is the significance of the Duffy blood group protein in relation to P.vivax malaria?
It provides protection against P.vivax malaria
What is the primary mode of transmission of malaria parasites?
Female Anopheles mosquito bites
What happens to schizonts when the blood is kept at a warmer temperature?
They rupture
What is the role of animal reservoirs in the transmission of malaria?
They have no important role in transmission
Why do Plasmodium vivax or Plasmodium ovale resemble Plasmodium malariae when left in EDTA for several hours?
The acid in the sample shrinks the erythrocytes
What is the least problematic anticoagulant for malarial blood smears?
EDTA
How does climate influence the life cycle of malaria?
It affects all three components of the life cycle
What is an important factor influencing the intensity of transmission of malaria?
The species of Anopheles mosquito present in the area
At what pH should malarial blood smears be stained?
7.2
What type of organisms are Apicomplexans?
Protozoa
What stage of the Plasmodium life cycle is characterized by the presence of ring-form trophozoites?
Erythrocytic stage
What is the primary target of pre-erythrocytic vaccine candidates?
Sporozoite
Which of the following antimalarial drugs is effective against the sporozoite stage?
Primaquine
What is the main reason why malaria vaccine development is challenging?
Many factors, including immunity, resistance, and relapse
Which of the following populations is less susceptible to vivax malaria?
West Africans and their descendants
What is the characteristic of the symptoms in relapse compared to the primary attack?
Less severe
Which of the following antimalarial drugs is considered the most effective?
Chloroquine
Test your knowledge on the different forms of the Knowlesi malaria parasite, including its life cycle, hosts, and stages of development. Learn about the roles of merozoites, sporozoites, and other forms in the infection process. Understand the heteroxenous lifecycle of the parasite.
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