Knowlesi Malaria Parasite Life Cycle
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Questions and Answers

What is the term for the early stage of the parasite's growth inside the erythrocyte?

  • Trophozoite (correct)
  • Segmenter
  • Schizont
  • Merozoite
  • What is the result of the multiple rounds of nuclear division without cytokinesis in the trophic period?

  • Merozoites
  • Trophozoites
  • Erythrocyte
  • Schizont (correct)
  • What is the primary function of the trophozoite during its growth inside the erythrocyte?

  • Ingesting host cytoplasm (correct)
  • Breaking down erythrocyte walls
  • Producing hemoglobin
  • Reproducing
  • Which of the following is NOT a stage in the blood-stage replicative cycle of the malaria parasite?

    <p>Meiosis</p> Signup and view all the answers

    What percentage of malaria cases are attributed to Plasmodium falciparum?

    <p>50%</p> Signup and view all the answers

    What is the estimated number of children under five who die from malaria every day in Africa?

    <p>3000</p> Signup and view all the answers

    What is the form of the parasite that invades erythrocytes?

    <p>Merozoite</p> Signup and view all the answers

    Which stage of the parasite undergoes exflagellation to form gametes?

    <p>Microgametocyte</p> Signup and view all the answers

    What is the result of the schizogony process in the hepatocyte?

    <p>Formation of merozoites</p> Signup and view all the answers

    In which stage of the parasite's life cycle does mitosis occur?

    <p>Oocyst</p> Signup and view all the answers

    What is the term for the life cycle of the parasite in the vertebrate host?

    <p>Erythrocytic cycle</p> Signup and view all the answers

    What is the result of the fusion of ingested gametes in the mosquito gut?

    <p>Formation of zygote</p> Signup and view all the answers

    What is the advantage of having sickle cell trait in relation to falciparum malaria?

    <p>Reduced risk of acute illness</p> Signup and view all the answers

    What is the significance of the Duffy blood group protein in relation to P.vivax malaria?

    <p>It provides protection against P.vivax malaria</p> Signup and view all the answers

    What is the primary mode of transmission of malaria parasites?

    <p>Female Anopheles mosquito bites</p> Signup and view all the answers

    What happens to schizonts when the blood is kept at a warmer temperature?

    <p>They rupture</p> Signup and view all the answers

    What is the role of animal reservoirs in the transmission of malaria?

    <p>They have no important role in transmission</p> Signup and view all the answers

    Why do Plasmodium vivax or Plasmodium ovale resemble Plasmodium malariae when left in EDTA for several hours?

    <p>The acid in the sample shrinks the erythrocytes</p> Signup and view all the answers

    What is the least problematic anticoagulant for malarial blood smears?

    <p>EDTA</p> Signup and view all the answers

    How does climate influence the life cycle of malaria?

    <p>It affects all three components of the life cycle</p> Signup and view all the answers

    What is an important factor influencing the intensity of transmission of malaria?

    <p>The species of Anopheles mosquito present in the area</p> Signup and view all the answers

    At what pH should malarial blood smears be stained?

    <p>7.2</p> Signup and view all the answers

    What type of organisms are Apicomplexans?

    <p>Protozoa</p> Signup and view all the answers

    What stage of the Plasmodium life cycle is characterized by the presence of ring-form trophozoites?

    <p>Erythrocytic stage</p> Signup and view all the answers

    What is the primary target of pre-erythrocytic vaccine candidates?

    <p>Sporozoite</p> Signup and view all the answers

    Which of the following antimalarial drugs is effective against the sporozoite stage?

    <p>Primaquine</p> Signup and view all the answers

    What is the main reason why malaria vaccine development is challenging?

    <p>Many factors, including immunity, resistance, and relapse</p> Signup and view all the answers

    Which of the following populations is less susceptible to vivax malaria?

    <p>West Africans and their descendants</p> Signup and view all the answers

    What is the characteristic of the symptoms in relapse compared to the primary attack?

    <p>Less severe</p> Signup and view all the answers

    Which of the following antimalarial drugs is considered the most effective?

    <p>Chloroquine</p> Signup and view all the answers

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