Knowlesi Malaria Parasite Life Cycle

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Questions and Answers

What is the term for the early stage of the parasite's growth inside the erythrocyte?

  • Trophozoite (correct)
  • Segmenter
  • Schizont
  • Merozoite

What is the result of the multiple rounds of nuclear division without cytokinesis in the trophic period?

  • Merozoites
  • Trophozoites
  • Erythrocyte
  • Schizont (correct)

What is the primary function of the trophozoite during its growth inside the erythrocyte?

  • Ingesting host cytoplasm (correct)
  • Breaking down erythrocyte walls
  • Producing hemoglobin
  • Reproducing

Which of the following is NOT a stage in the blood-stage replicative cycle of the malaria parasite?

<p>Meiosis (B)</p> Signup and view all the answers

What percentage of malaria cases are attributed to Plasmodium falciparum?

<p>50% (B)</p> Signup and view all the answers

What is the estimated number of children under five who die from malaria every day in Africa?

<p>3000 (B)</p> Signup and view all the answers

What is the form of the parasite that invades erythrocytes?

<p>Merozoite (B)</p> Signup and view all the answers

Which stage of the parasite undergoes exflagellation to form gametes?

<p>Microgametocyte (B)</p> Signup and view all the answers

What is the result of the schizogony process in the hepatocyte?

<p>Formation of merozoites (A)</p> Signup and view all the answers

In which stage of the parasite's life cycle does mitosis occur?

<p>Oocyst (D)</p> Signup and view all the answers

What is the term for the life cycle of the parasite in the vertebrate host?

<p>Erythrocytic cycle (D)</p> Signup and view all the answers

What is the result of the fusion of ingested gametes in the mosquito gut?

<p>Formation of zygote (D)</p> Signup and view all the answers

What is the advantage of having sickle cell trait in relation to falciparum malaria?

<p>Reduced risk of acute illness (A)</p> Signup and view all the answers

What is the significance of the Duffy blood group protein in relation to P.vivax malaria?

<p>It provides protection against P.vivax malaria (D)</p> Signup and view all the answers

What is the primary mode of transmission of malaria parasites?

<p>Female Anopheles mosquito bites (D)</p> Signup and view all the answers

What happens to schizonts when the blood is kept at a warmer temperature?

<p>They rupture (D)</p> Signup and view all the answers

What is the role of animal reservoirs in the transmission of malaria?

<p>They have no important role in transmission (D)</p> Signup and view all the answers

Why do Plasmodium vivax or Plasmodium ovale resemble Plasmodium malariae when left in EDTA for several hours?

<p>The acid in the sample shrinks the erythrocytes (A)</p> Signup and view all the answers

What is the least problematic anticoagulant for malarial blood smears?

<p>EDTA (D)</p> Signup and view all the answers

How does climate influence the life cycle of malaria?

<p>It affects all three components of the life cycle (B)</p> Signup and view all the answers

What is an important factor influencing the intensity of transmission of malaria?

<p>The species of Anopheles mosquito present in the area (B)</p> Signup and view all the answers

At what pH should malarial blood smears be stained?

<p>7.2 (C)</p> Signup and view all the answers

What type of organisms are Apicomplexans?

<p>Protozoa (B)</p> Signup and view all the answers

What stage of the Plasmodium life cycle is characterized by the presence of ring-form trophozoites?

<p>Erythrocytic stage (D)</p> Signup and view all the answers

What is the primary target of pre-erythrocytic vaccine candidates?

<p>Sporozoite (A)</p> Signup and view all the answers

Which of the following antimalarial drugs is effective against the sporozoite stage?

<p>Primaquine (B)</p> Signup and view all the answers

What is the main reason why malaria vaccine development is challenging?

<p>Many factors, including immunity, resistance, and relapse (A)</p> Signup and view all the answers

Which of the following populations is less susceptible to vivax malaria?

<p>West Africans and their descendants (B)</p> Signup and view all the answers

What is the characteristic of the symptoms in relapse compared to the primary attack?

<p>Less severe (B)</p> Signup and view all the answers

Which of the following antimalarial drugs is considered the most effective?

<p>Chloroquine (D)</p> Signup and view all the answers

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