Klebsiella
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Questions and Answers

What are the virulence factors associated with Salmonella?

Enterotoxin, resistance to stomach acid, ability to disseminate, high infective dose

What is the most common form of Salmonella disease?

Salmonella Enterocolitis – inflammation of the mucous membranes of the small and large intestine

What are the symptoms of Salmonella Enterocolitis?

Nausea, headache, vomiting, profuse diarrhea, and low-grade fever

What is Salmonella Bacteremia?

<p>A condition caused by non-typhoidal Salmonella that spreads from the gastrointestinal tract, leading to prolonged fever with intermittent bacteremia</p> Signup and view all the answers

What are the possible complications of Salmonella Bacteremia?

<p>Metastatic infection of bones, joints, meninges, or cardiovascular system</p> Signup and view all the answers

What is the most common type of Salmonella enteric fever?

<p>Typhoid fever, caused by S. Typhi</p> Signup and view all the answers

What is the most virulent species of Staph?

<p>Staphylococcus aureus</p> Signup and view all the answers

What are the symptoms of Typhoid fever?

<p>Fever, headache, loss of appetite, weakness, splenomegaly, abdominal pain</p> Signup and view all the answers

What are the normal flora (colonizers) of the skin and mucus membranes?

<p>Staphylococcus and Streptococcus</p> Signup and view all the answers

What are the routes of infection for Staphylococcus aureus?

<p>Trauma/abrasion, person-to-person, nosocomial, ingestion of bacteria or toxin</p> Signup and view all the answers

What are the virulence factors of Staphylococcus aureus?

<p>Enzymes, cytolytic toxins, protein A, enterotoxins</p> Signup and view all the answers

What are the typical characteristics of skin and wound infections caused by Staphylococcus aureus?

<p>Suppurative (pus-filled) and surrounded by necrotic tissue</p> Signup and view all the answers

What are the symptoms of food poisoning caused by Staphylococcus aureus?

<p>Nausea, vomiting, cramping, diarrhea, and headache</p> Signup and view all the answers

What is the most common age group affected by Scalded Skin Syndrome caused by Staphylococcus aureus?

<p>Children &lt; 5 years old</p> Signup and view all the answers

What are the common causes of nosocomial infections?

<p>Klebsiella and Proteus spp.</p> Signup and view all the answers

What is the most common isolate of Proteus?

<p>P. mirabilis &amp; P. vulgaris</p> Signup and view all the answers

How is Yersinia pestis transmitted?

<p>Via rat flea bites, airborne droplets (pneumonic plague), ingestion of contaminated animal tissue</p> Signup and view all the answers

What are the characteristics of Yersinia pestis?

<p>Highly virulent, antiphagocytic capsule, exotoxins, coagulase, fibrinolysin</p> Signup and view all the answers

What is the optimal growth temperature for Yersinia pestis?

<p>25-30 degrees Celsius</p> Signup and view all the answers

What are the symptoms of bubonic plague?

<p>Acute febrile disease, painful buboes, septicemia</p> Signup and view all the answers

How is pneumonic plague transmitted?

<p>Infectious droplets (sneezing, coughing)</p> Signup and view all the answers

What are the symptoms of pneumonic plague?

<p>Malaise, pulmonary signs, rapidly fatal</p> Signup and view all the answers

What are the characteristics of Vibrio cholerae?

<p>Curved gram-negative rod, found in water, associated with recent consumption of raw seafood and recent immigration or foreign travel</p> Signup and view all the answers

What are the major virulence factors of Pyogenes?

<p>M protein, Streptolysin O, Streptolysin S, DNase, Streptokinase, Hyaluronidase, Spreading factor, Erythrogenic toxin</p> Signup and view all the answers

What are the nonsuppurative sequelae of Strep. Pyogenes infections?

<p>Rheumatic fever, Acute glomerulonephritis</p> Signup and view all the answers

What are the symptoms of rheumatic fever?

<p>Fever, inflammation of joints, heart, CNS, sub-Q tissues</p> Signup and view all the answers

What are the symptoms of acute glomerulonephritis?

<p>Edema, hypertension, hematuria, proteinuria</p> Signup and view all the answers

What are the major routes of infection for Neisseria gonorrhoeae?

<p>Sexual transmission, vertical transmission during vaginal delivery</p> Signup and view all the answers

What are the major symptoms of gonorrhea in males?

<p>Male urethritis, purulent discharge, dysuria</p> Signup and view all the answers

What are the major symptoms of gonorrhea in females?

<p>Vaginal discharge, bleeding, dysuria, lower abdominal pain</p> Signup and view all the answers

Flashcards

What is Salmonella Enterocolitis?

Inflammation of the mucous membranes of the small and large intestine caused by Salmonella.

What is Salmonella Bacteremia?

A condition caused by non-typhoidal Salmonella spreading from the gastrointestinal tract, resulting in prolonged fever and intermittent bacteremia.

What is the most common type of Salmonella enteric fever?

Typhoid fever, caused by S. Typhi, is the most common form of Salmonella enteric fever.

What's the most virulent Staph species?

Staphylococcus aureus is the most virulent species of Staphylococcus.

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What are the normal flora of skin and mucous membranes?

Staphylococcus and Streptococcus are common normal flora (colonizers) of the skin and mucus membranes.

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How do Staph aureus skin infections appear?

Suppurative (pus-filled) wounds surrounded by necrotic tissue are characteristic of skin and wound infections caused by Staphylococcus aureus.

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Who is most affected by Scalded Skin Syndrome?

Children under 5 years old are most commonly affected by Scalded Skin Syndrome caused by Staphylococcus aureus.

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What causes many hospital-acquired infections?

Klebsiella and Proteus spp. are common causes of nosocomial infections.

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What are the common types of Proteus?

P. mirabilis & P. vulgaris are the most common isolates of Proteus.

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How is Yersinia pestis transmitted?

Yersinia pestis is a highly virulent bacterium transmitted via rat flea bites, airborne droplets (pneumonic plague), or ingestion of contaminated animal tissue.

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What makes Yersinia pestis dangerous?

Yersinia pestis characteristics include a highly virulent nature, antiphagocytic capsule, exotoxins, coagulase, and fibrinolysin.

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What are the symptoms of bubonic plague?

Bubonic plague is an acute febrile disease characterized by painful buboes, which are swollen lymph nodes, and septicemia.

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How is pneumonic plague transmitted?

Pneumonic plague spreads via infectious droplets, such as those from sneezing or coughing.

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What is Vibrio cholerae?

Vibrio cholerae is a curved gram-negative rod found in water. Its presence is often linked to consuming raw seafood and recent travel.

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What are the virulence factors of Pyogenes?

M protein, Streptolysin O, Streptolysin S, DNase, Streptokinase, Hyaluronidase, Spreading factor, and Erythrogenic toxin are major virulence factors of Pyogenes.

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What complications can follow Strep Pyogenes infections?

Rheumatic fever and Acute glomerulonephritis are nonsuppurative sequelae of Strep. Pyogenes infections.

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What are the symptoms of rheumatic fever?

Fever, inflammation of joints, heart, CNS, and sub-Q tissues are symptoms of rheumatic fever.

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What are the signs of acute glomerulonephritis?

Edema, hypertension, hematuria, and proteinuria are symptoms of acute glomerulonephritis.

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How is Neisseria gonorrhoeae transmitted?

Neisseria gonorrhoeae is typically transmitted sexually or vertically during vaginal delivery.

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What are the symptoms of gonorrhea in males?

Male urethritis, purulent discharge, and dysuria are common symptoms of gonorrhea in males.

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What are the symptoms of gonorrhea in females?

Vaginal discharge, bleeding, dysuria, and lower abdominal pain are common symptoms of gonorrhea in females.

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What are the symptoms of Salmonella Enterocolitis?

Nausea, headache, vomiting, profuse diarrhea, and low-grade fever are common symptoms of Salmonella Enterocolitis.

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What are the virulence factors of Salmonella?

Enterotoxin, resistance to stomach acid, ability to disseminate, and high infective dose are virulence factors associated with Salmonella.

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What are the symptoms of Typhoid fever?

Fever, headache, loss of appetite, weakness, splenomegaly, and abdominal pain are symptoms of Typhoid fever.

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How can you get infected with Staphylococcus aureus?

Trauma/abrasion, person-to-person contact, nosocomial infections, and ingestion of bacteria or toxins are routes of infection for Staphylococcus aureus.

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What are the virulence factors of Staphylococcus aureus?

Enzymes, cytolytic toxins, protein A, and enterotoxins are virulence factors of Staphylococcus aureus.

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What are the symptoms of food poisoning by Staphylococcus aureus?

Nausea, vomiting, cramping, diarrhea, and a headache are common symptoms of food poisoning by Staphylococcus aureus.

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