Kinetics: Rate Constants and Enzyme Efficiency Quiz
13 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What type of inhibitors bind permanently to the enzyme and stop the whole pathway?

Irreversible inhibitors

What type of inhibition involves the inhibitor binding at either the enzyme or the enzyme-substrate complex?

Mixed inhibition

What is the rate constant (k) for a first-order reaction involving only 1 reactant?

k

What do reversible inhibitors do to the enzyme pathway?

<p>Slow down the EZ pathway</p> Signup and view all the answers

What is the rate expression for a second-order reaction involving 2 reactants?

<p>v=k[A][B]</p> Signup and view all the answers

What assumption is made in the steady-state assumption for enzyme kinetics?

<p>Assume that over most of the reaction course [ES] is small &amp; does not change, d[ES]/dt=0</p> Signup and view all the answers

What does the turnover number (kcat) represent?

<p>Max velocity per enzyme molecule per unit of time</p> Signup and view all the answers

What is the nature of the R1 side chain critical for in the hydrolysis of a peptide bond by proteolytic enzymes?

<p>The nature of the R1 side chain is critical for the hydrolysis of a peptide bond by proteolytic enzymes.</p> Signup and view all the answers

How can enzyme activity be controlled?

<p>Enzyme activity can be controlled by allosteric regulation, covalent modification, and inhibitors.</p> Signup and view all the answers

What is the function of allosteric effectors in enzyme regulation?

<p>Allosteric effectors can bind at allosteric sites to either activate (favor R state) or inhibit (favor T state) enzyme activity.</p> Signup and view all the answers

What is the mechanism of action of competitive inhibitors?

<p>Competitive inhibitors compete with the substrate for binding at the active site of the enzyme.</p> Signup and view all the answers

How do non-allosteric site inhibitors affect enzyme activity?

<p>Non-allosteric site inhibitors decrease the velocity and Vmax of the reaction by decreasing the kcat.</p> Signup and view all the answers

What is the role of reversible covalent modification in enzyme regulation?

<p>Reversible covalent modification, such as phosphorylation and dephosphorylation, is a common mechanism to regulate enzyme activity.</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Open
Browser
Browser