Podcast
Questions and Answers
What type of inhibitors bind permanently to the enzyme and stop the whole pathway?
What type of inhibitors bind permanently to the enzyme and stop the whole pathway?
Irreversible inhibitors
What type of inhibition involves the inhibitor binding at either the enzyme or the enzyme-substrate complex?
What type of inhibition involves the inhibitor binding at either the enzyme or the enzyme-substrate complex?
Mixed inhibition
What is the rate constant (k) for a first-order reaction involving only 1 reactant?
What is the rate constant (k) for a first-order reaction involving only 1 reactant?
k
What do reversible inhibitors do to the enzyme pathway?
What do reversible inhibitors do to the enzyme pathway?
What is the rate expression for a second-order reaction involving 2 reactants?
What is the rate expression for a second-order reaction involving 2 reactants?
What assumption is made in the steady-state assumption for enzyme kinetics?
What assumption is made in the steady-state assumption for enzyme kinetics?
What does the turnover number (kcat) represent?
What does the turnover number (kcat) represent?
What is the nature of the R1 side chain critical for in the hydrolysis of a peptide bond by proteolytic enzymes?
What is the nature of the R1 side chain critical for in the hydrolysis of a peptide bond by proteolytic enzymes?
How can enzyme activity be controlled?
How can enzyme activity be controlled?
What is the function of allosteric effectors in enzyme regulation?
What is the function of allosteric effectors in enzyme regulation?
What is the mechanism of action of competitive inhibitors?
What is the mechanism of action of competitive inhibitors?
How do non-allosteric site inhibitors affect enzyme activity?
How do non-allosteric site inhibitors affect enzyme activity?
What is the role of reversible covalent modification in enzyme regulation?
What is the role of reversible covalent modification in enzyme regulation?
