Podcast
Questions and Answers
What percentage of cases of terminal renal failure are attributed to Glomerulonephritis?
What percentage of cases of terminal renal failure are attributed to Glomerulonephritis?
- 2/3
- 1/2
- 1/3 (correct)
- 3/4
Which of the following is an example of an exogenous antigen that can cause Glomerulonephritis?
Which of the following is an example of an exogenous antigen that can cause Glomerulonephritis?
- Systemic Lupus Erythematosus (SLE)
- Goodpasture's syndrome
- Group A β-haemolytic Strep (correct)
- Focal segmental glomerulosclerosis
What is the primary mechanism of glomerular damage in Glomerulonephritis?
What is the primary mechanism of glomerular damage in Glomerulonephritis?
- Cell-mediated glomerular damage
- Deposition of anti-GBM
- Deposition of circulating Immune complex
- In situ formation of immune complex (correct)
What is the term used to describe the kidney as the predominant organ involved in Glomerulonephritis?
What is the term used to describe the kidney as the predominant organ involved in Glomerulonephritis?
What is the term used to describe the inflammatory response in Glomerulonephritis, characterized by hypercellularity, basement membrane thickening, and hyalinisation and sclerosis?
What is the term used to describe the inflammatory response in Glomerulonephritis, characterized by hypercellularity, basement membrane thickening, and hyalinisation and sclerosis?
Which of the following is NOT a principal function of the kidney?
Which of the following is NOT a principal function of the kidney?
What is the primary cause of glomerular capillary damage in kidney diseases?
What is the primary cause of glomerular capillary damage in kidney diseases?
Which of the following symptoms is NOT typically associated with renal tract disease?
Which of the following symptoms is NOT typically associated with renal tract disease?
What is the result of severe damage to all four structures of the kidney?
What is the result of severe damage to all four structures of the kidney?
Which part of the kidney is most sensitive to immune reactions?
Which part of the kidney is most sensitive to immune reactions?
What is the definition of nephritis?
What is the definition of nephritis?
What is the primary characteristic of nephrotic syndrome?
What is the primary characteristic of nephrotic syndrome?
What is the result of increased catabolism of protein in the kidney in nephrotic syndrome?
What is the result of increased catabolism of protein in the kidney in nephrotic syndrome?
What is the primary goal of management in acute nephritic syndrome?
What is the primary goal of management in acute nephritic syndrome?
What is the effect of hypoalbuminaemia on plasma oncotic pressure?
What is the effect of hypoalbuminaemia on plasma oncotic pressure?
What is the result of increased synthesis of lipid protein in the liver in nephrotic syndrome?
What is the result of increased synthesis of lipid protein in the liver in nephrotic syndrome?
What is the primary reason for oedema in nephrotic syndrome?
What is the primary reason for oedema in nephrotic syndrome?
What is the primary indication for dialysis in chronic renal failure?
What is the primary indication for dialysis in chronic renal failure?
Which of the following is a characteristic of anaemia in chronic renal failure?
Which of the following is a characteristic of anaemia in chronic renal failure?
What is the common underlying mechanism of electrolyte and acid-base disorders in chronic renal failure?
What is the common underlying mechanism of electrolyte and acid-base disorders in chronic renal failure?
Which of the following is a common complication of chronic renal failure?
Which of the following is a common complication of chronic renal failure?
What is the most common cause of chronic renal failure?
What is the most common cause of chronic renal failure?
Which of the following kidney structures is most prone to immunological damage?
Which of the following kidney structures is most prone to immunological damage?
The kidneys' principal function is only to eliminate waste materials.
The kidneys' principal function is only to eliminate waste materials.
Nephritis is a disease that only affects the renal tubule system.
Nephritis is a disease that only affects the renal tubule system.
Severe damage to only one of the kidney's structures can lead to chronic renal disease.
Severe damage to only one of the kidney's structures can lead to chronic renal disease.
Dysuria is not a symptom of renal tract disease.
Dysuria is not a symptom of renal tract disease.
The interstitium is resistant to toxic and infectious agents.
The interstitium is resistant to toxic and infectious agents.
Renal failure is a disease that only affects the glomeruli.
Renal failure is a disease that only affects the glomeruli.
Glomerulonephritis is a term that refers to a bilateral, asymmetrical injury to the glomerulus
Glomerulonephritis is a term that refers to a bilateral, asymmetrical injury to the glomerulus
Primary Glomerulonephritis involves systemic diseases with glomerular involvement
Primary Glomerulonephritis involves systemic diseases with glomerular involvement
In situ formation of immune complexes is a mechanism of glomerular damage in Glomerulonephritis
In situ formation of immune complexes is a mechanism of glomerular damage in Glomerulonephritis
Acute nephritic syndrome is a characteristic of chronic renal failure
Acute nephritic syndrome is a characteristic of chronic renal failure
Group A β-haemolytic Strep is an example of an endogenous antigen that can cause Glomerulonephritis
Group A β-haemolytic Strep is an example of an endogenous antigen that can cause Glomerulonephritis
Acute nephritic syndrome is characterized by severe proteinuria and generally leads to chronic kidney dysfunction.
Acute nephritic syndrome is characterized by severe proteinuria and generally leads to chronic kidney dysfunction.
In nephrotic syndrome, there is a decreased synthesis of lipid protein in the liver.
In nephrotic syndrome, there is a decreased synthesis of lipid protein in the liver.
The primary goal of management in acute nephritic syndrome is to reduce proteinuria.
The primary goal of management in acute nephritic syndrome is to reduce proteinuria.
In acute nephritic syndrome, the glomeruli are hypocellular.
In acute nephritic syndrome, the glomeruli are hypocellular.
Hyperkalaemia is typically treated with nephrotoxic drugs.
Hyperkalaemia is typically treated with nephrotoxic drugs.
Oedema in nephrotic syndrome is primarily due to hypervolemia.
Oedema in nephrotic syndrome is primarily due to hypervolemia.
Chronic renal failure is commonly caused by kidney stones.
Chronic renal failure is commonly caused by kidney stones.
Acute renal failure is a common complication of acute nephritic syndrome.
Acute renal failure is a common complication of acute nephritic syndrome.
Renal osteodystrophy is a complication of chronic renal failure that is caused by EPO deficiency.
Renal osteodystrophy is a complication of chronic renal failure that is caused by EPO deficiency.
The interstitium is the most prone to immunological damage in the kidney.
The interstitium is the most prone to immunological damage in the kidney.
Severe metabolic acidosis is defined as a pH of 4.0 mmol/L.
Severe metabolic acidosis is defined as a pH of 4.0 mmol/L.
Dialysis is indicated for patients with a pH of 40 mmol/L.
Dialysis is indicated for patients with a pH of 40 mmol/L.
Flashcards are hidden until you start studying
Study Notes
- Kidney diseases can be associated with abnormalities of the glomerular capillary or the renal tubule system.
- The kidney's principal function includes eliminating waste materials, regulating fluid and electrolyte balance, and endocrine function.
- Symptoms suggesting renal tract disease include dysuria, haematuria, urinary retention, alteration of urine volume, and pain situated along the renal tract.
- Diseases of the kidney can be classified into four categories: glomeruli (immunologically mediated), tubules (toxic/infectious agents), interstitium (toxic/infectious agents), and blood vessels (damage to blood supply).
- Severe damage to all four structures can lead to chronic renal diseases and renal failure.
- Nephritis is the inflammation of any part of the kidney, including glomerulonephritis, interstitial nephritis, and pyelonephritis.
- Glomerulonephritis is a general term for a group of disorders characterized by bilateral, symmetrical immunologically mediated injury to the glomerulus, accounting for 1/3 cases of terminal renal failure.
- Glomerulonephritis can be primary (kidney is the predominant organ involved) or secondary (systemic diseases with glomerular involvement).
- The pathology of acute nephritic syndrome includes diffuse proliferative glomerulonephritis, characterized by hypercellular glomeruli.
- Management of acute nephritic syndrome includes supportive measures until spontaneous recovery, hypertension management, fluid balance monitoring, and management of life-threatening complications.
- Clinical features of acute nephritic syndrome include haematuria, proteinuria, hypertension, oedema, oliguria, and uraemia.
- Nephrotic syndrome is characterized by severe proteinuria, leading to chronic kidney dysfunction, and is often caused by GBM damage, loss of electrostatic and physical barriers.
- Diagnostic investigations for nephrotic syndrome include proteinuria (>3.5g/24 h in adults), hyperlipidaemia, hypoalbuminaemia, and oliguria.
- Acute renal failure treatment involves correcting reversible underlying factors, treating hyperkalaemia, and dialysis, with indications including hyperkalaemia, severe metabolic acidosis, and uraemic syndrome.
- Chronic renal failure is often associated with haematological and metabolic complications, including anaemia, renal osteodystrophy, electrolyte/acid-base disorders, and hyperkalaemia.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
