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Questions and Answers
Which of the following statements about the urinary system is TRUE?
Which of the following statements about the urinary system is TRUE?
Which of the following scenarios is TRUE? Since the podocytes prevent the excretion of larger organic compounds (like blood cells and large proteins), but still allow smaller organic compounds and ions through.
Which of the following scenarios is TRUE? Since the podocytes prevent the excretion of larger organic compounds (like blood cells and large proteins), but still allow smaller organic compounds and ions through.
Which of the following statements is TRUE about filtration? The filtration of substances out of the blood and into the glomerular capsule is directed and coordinated by difference in glomerular hydrostatic pressure.
Which of the following statements is TRUE about filtration? The filtration of substances out of the blood and into the glomerular capsule is directed and coordinated by difference in glomerular hydrostatic pressure.
What is the most accurate measurement of GFR?
What is the most accurate measurement of GFR?
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What is the common indicator of renal failure?
What is the common indicator of renal failure?
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Which of the following is NOT a type of acute renal failure?
Which of the following is NOT a type of acute renal failure?
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Chronic kidney disease is often associated with permanent damage to the nephrons.
Chronic kidney disease is often associated with permanent damage to the nephrons.
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The most common risk factors for chronic kidney disease are diabetes and hypertension
The most common risk factors for chronic kidney disease are diabetes and hypertension
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Life-supporting treatments for kidney failure include dialysis and kidney transplantation.
Life-supporting treatments for kidney failure include dialysis and kidney transplantation.
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Creatinine clearance is more accurate than inulin clearance for measuring GFR
Creatinine clearance is more accurate than inulin clearance for measuring GFR
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The urinary system has three important functions: excretion, homeostatic regulation, and elimination. Which of the following statements about the urinary system is TRUE?
The urinary system has three important functions: excretion, homeostatic regulation, and elimination. Which of the following statements about the urinary system is TRUE?
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Nephrons are the basic functional units of the kidneys. Their proper functioning is crucial to the maintenance of homeostasis. Since the podocytes prevent the excretion of larger organic compounds (like blood cells and large proteins), but still allow smaller organic compounds and ions through, which of the following scenarios is TRUE?
Nephrons are the basic functional units of the kidneys. Their proper functioning is crucial to the maintenance of homeostasis. Since the podocytes prevent the excretion of larger organic compounds (like blood cells and large proteins), but still allow smaller organic compounds and ions through, which of the following scenarios is TRUE?
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The filtration of substances out of the blood and into the glomerular capsule is directed and coordinated by differences in glomerular hydrostatic pressure. Which of the following statements is TRUE about filtration? (GHP = glomerular hydrostatic pressure, CP = colloid pressure, GFR = glomerular filtration rate).
The filtration of substances out of the blood and into the glomerular capsule is directed and coordinated by differences in glomerular hydrostatic pressure. Which of the following statements is TRUE about filtration? (GHP = glomerular hydrostatic pressure, CP = colloid pressure, GFR = glomerular filtration rate).
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What is the main function of the kidney?
What is the main function of the kidney?
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What is the name of the functional unit of the kidney?
What is the name of the functional unit of the kidney?
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What is the difference between acute and chronic kidney failure?
What is the difference between acute and chronic kidney failure?
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What is Glomerular Filtration Rate (GFR) and what does it indicate?
What is Glomerular Filtration Rate (GFR) and what does it indicate?
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Kidney disease is always a result of diabetes or hypertension.
Kidney disease is always a result of diabetes or hypertension.
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End-stage kidney disease requires life-supporting treatments.
End-stage kidney disease requires life-supporting treatments.
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Study Notes
Kidney Anatomy and Function
- Kidneys perform excretion, elimination, and homeostatic regulation
- Blood is circulated through the kidney, filtered by nephrons, and substances reabsorbed/secreted to maintain solute and water balance.
- Kidneys receive 20-25% of cardiac output for oxygen and nutrient delivery.
- Blood flows through renal arteries, segmental arteries, interlobar arteries, arcuate arteries, cortical radiate arteries, and afferent arterioles to enter glomerular capillaries.
- Waste- and nutrient-poor blood, now oxygenated, flows through peritubular capillaries to nourish nephrons.
- Deoxygenated blood exits via venules and veins
Blood Flow Through the Kidney
- Blood enters the kidney via renal arteries
- Branches into segmental, interlobar, arcuate, cortical radiate arteries, and then afferent arterioles.
- Blood enters the glomerulus (a capillary network) where filtration occurs.
- Blood leaves the glomerulus through efferent arterioles.
- Blood then flows through the peritubular capillaries and is returned to the heart through venules and veins
- Waste products and excess solutes are removed from the blood in nephrons
Nephron Function
- The nephron is the basic functional unit of the kidney.
- Excretion: Filters solutes from blood into tubular fluid (across glomeruli). This includes nitrogenous wastes (urea, creatinine, ammonia, uric acid).
- Homeostatic regulation: reabsorbs useful substances (glucose, amino acids, electrolytes) and secretes excess substances.
- Kidneys regulate levels of sodium, potassium, hydrogen, and bicarbonate ions.
- Water, often following solute concentrations, also adjusted
- Elimination: Urine is transported out of the body.
- Filtration is a key process: substances move from blood into glomerular capsule, driven by glomerular hydrostatic pressure
Glomerular Filtration Rate (GFR)
- GFR: is a measure of kidney function.
- A normal GFR is between 100 and 130 ml/min/1.73m2
- GFR is determined by the volume of serum filtered per minute.
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Description
Test your knowledge on the anatomy and function of the kidneys, including blood flow, filtration, and homeostasis. This quiz covers the structure and processes involved in maintaining fluid and electrolyte balance in the body.