Ketogenesis Pathway Overview
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Questions and Answers

What is the primary role of insulin in fatty acid metabolism?

  • Increasing release of free fatty acids
  • Activating lipolysis
  • Transporting fatty acids across the inner mitochondrial membrane
  • Activating lipogenesis (correct)

In diabetic ketoacidosis, which predominant ketone body is often elevated?

  • Malate
  • Acetone
  • Malonyl-CoA
  • Acetoacetate (correct)

Which enzyme catalyzes the conversion of acetoacetate to β-hydroxybutyrate?

  • Acetyl-CoA carboxylase
  • Carnitine palmitoyltransferase I
  • β-hydroxybutyrate dehydrogenase (correct)
  • Pyruvate carboxylase

What is the main ATP-generating process when palmitate is metabolized via the citric acid cycle compared to ketone bodies formation?

<p>Citric acid cycle generates more ATP (D)</p> Signup and view all the answers

In which organelle do very long chain fatty acids undergo oxidation?

<p>Peroxisomes (A)</p> Signup and view all the answers

What metabolic condition is associated with hypoglycemia due to impaired β-oxidation?

<p>Diabetic ketoacidosis (D)</p> Signup and view all the answers

β-oxidation of fatty acids in the mitochondria results in the production of which molecule that enters the citric acid cycle?

<p><strong>β</strong>-oxidation (D)</p> Signup and view all the answers

β-oxidation requires the activation of fatty acids to which form before transportation across the inner mitochondrial membrane?

<p><strong>β</strong>-acyl CoA (A)</p> Signup and view all the answers

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