Podcast
Questions and Answers
What initiates the process of ketogenesis in the liver?
What initiates the process of ketogenesis in the liver?
- Decreased fatty acid oxidation in the liver
- Increase in glucose supply to the liver
- Increased utilization of acetyl-CoA by the TCA cycle
- Increased supply of free fatty acids due to lipolysis (correct)
Which process is directly inhibited to promote ketogenesis?
Which process is directly inhibited to promote ketogenesis?
- Utilization of acetyl-CoA by the TCA cycle (correct)
- Beta-oxidation of fatty acids
- Lipolysis of triacylglycerols
- Transport of free fatty acids to the liver
What is the primary building block for the production of ketone bodies?
What is the primary building block for the production of ketone bodies?
- Glucose
- Acetyl-CoA (correct)
- Triacylglycerols
- Fatty acids
What role do ketone bodies serve in the body when glucose is scarce?
What role do ketone bodies serve in the body when glucose is scarce?
What is the fate of acyl-CoA in the liver during ketogenesis?
What is the fate of acyl-CoA in the liver during ketogenesis?
What happens to the ratio of anti-insulin to insulin in cases of starvation and severe uncontrolled diabetes?
What happens to the ratio of anti-insulin to insulin in cases of starvation and severe uncontrolled diabetes?
What role does fatty acyl-CoA play in fatty acid metabolism during starvation?
What role does fatty acyl-CoA play in fatty acid metabolism during starvation?
How does β-oxidation affect the TCA cycle under conditions of starvation?
How does β-oxidation affect the TCA cycle under conditions of starvation?
What is the consequence of the high NADH/NAD ratio during gluconeogenesis?
What is the consequence of the high NADH/NAD ratio during gluconeogenesis?
What metabolic shift occurs due to decreased glucose oxidation in starvation?
What metabolic shift occurs due to decreased glucose oxidation in starvation?
Flashcards
Ketogenesis
Ketogenesis
The process of producing ketone bodies from fatty acids.
Lipolysis
Lipolysis
Breakdown of triglycerides into free fatty acids (FFAs).
Acetyl-CoA
Acetyl-CoA
Key molecule produced during fatty acid breakdown, used in ketone body production and other metabolic pathways.
Ketone Bodies
Ketone Bodies
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Fatty Acid Oxidation
Fatty Acid Oxidation
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Starvation/Uncontrolled Diabetes
Starvation/Uncontrolled Diabetes
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Fatty Acid Metabolism (Starvation)
Fatty Acid Metabolism (Starvation)
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β-Oxidation Impact
β-Oxidation Impact
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Glucose Diversion (Starvation)
Glucose Diversion (Starvation)
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Oxaloacetate Conversion (Starvation)
Oxaloacetate Conversion (Starvation)
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