Podcast
Questions and Answers
What are other names for Keppra?
What are other names for Keppra?
What is the therapeutic class of Keppra?
What is the therapeutic class of Keppra?
Anticonvulsant
What is a rare use of Keppra?
What is a rare use of Keppra?
Subarachnoid hemorrhage
Keppra is used in the treatment of ______ seizures.
Keppra is used in the treatment of ______ seizures.
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What are some unlabeled uses of Keppra?
What are some unlabeled uses of Keppra?
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What is the maximum daily dose of Keppra?
What is the maximum daily dose of Keppra?
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Common dosage forms of Keppra include ______.
Common dosage forms of Keppra include ______.
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What is the starting dosage for adult partial seizures?
What is the starting dosage for adult partial seizures?
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Match the following dosages with their conditions:
Match the following dosages with their conditions:
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Study Notes
Keppra (Levetiracetam) Overview
- Also known as Levetiracetam and Elepsia.
- Classified as an anticonvulsant.
Therapeutic Uses
- Primarily used to control seizures related to epilepsy.
- Effective for:
- Myoclonic seizures
- Partial onset seizures
- Primary generalized tonic-clonic seizures
- Rarely used for subarachnoid hemorrhage.
Unlabeled Uses
- Utilized off-label to treat:
- Migraines
- Bipolar disorder
- New-onset pediatric epilepsy
- In Europe, highly effective as monotherapy for partial seizures.
Dosage Information
- Available in several forms:
- Extended-release tablet (Keppra XR)
- Immediate-release tablet
- Oral solution
- IV solution injection
- Maximum daily dosage is 3000 mg.
Adult Dosing Guidelines
- Pediatric and adult dosing employs various formulations:
- Partial seizures, adjunct treatment: Start at 500 mg PO/IV every 12 hours; can increase by 1000 mg/day every two weeks.
- Juvenile myoclonic epilepsy, adjunct treatment: Start at 500 mg PO/IV every 12 hours; increase similarly with a maximum of 3000 mg/day.
- Primary generalized tonic-clonic seizures, adjunct treatment: Same starting and dosing increase protocols as above.
- For renal dosing, adjust according to creatinine clearance (CrCl):
- CrCl 50-80: 500-1000 mg every 12 hours
- CrCl 30-50: 250-750 mg every 12 hours
- Important to avoid cutting, crushing, or chewing tablets and to taper doses gradually when discontinuing.
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Description
This quiz covers the overview and therapeutic uses of Keppra (Levetiracetam), an anticonvulsant used primarily for seizure control in epilepsy. It includes information on dosage forms, adult dosing guidelines, and some off-label uses. Test your knowledge about this essential medication and its applications.
