Podcast
Questions and Answers
Which medication is the most effective for symptomatic treatment?
Which medication is the most effective for symptomatic treatment?
- Amantadine
- Istradefylline
- Levodopa + Carbidopa (correct)
- Selegiline
What is the minimum amount of carbidopa required to prevent conversion of levodopa outside of the central nervous system (CNS)?
What is the minimum amount of carbidopa required to prevent conversion of levodopa outside of the central nervous system (CNS)?
- 50mg/day
- 100mg/day
- 25mg/day
- 75mg/day (correct)
What is the characteristic feature of long-term treatment with Levodopa/Carbidopa (Sinemet)?
What is the characteristic feature of long-term treatment with Levodopa/Carbidopa (Sinemet)?
- Psychotic disorder
- Dyskinesias
- Protein restriction
- Fluctuations in motor function (correct)
What is the recommended approach to combat the 'wearing off' phenomenon in patients on Levodopa/Carbidopa (Sinemet)?
What is the recommended approach to combat the 'wearing off' phenomenon in patients on Levodopa/Carbidopa (Sinemet)?
Which of the following is a characteristic of Huntington's Disease?
Which of the following is a characteristic of Huntington's Disease?
Which of the following drugs deplete dopamine and other monoamines from the axon terminus by preventing intraneuronal storage?
Which of the following drugs deplete dopamine and other monoamines from the axon terminus by preventing intraneuronal storage?
Which of the following drugs is a non-competitive NMDA antagonist and can be used alone or in combination with an anticholinesterase for the treatment of moderate-severe Alzheimer's Disease?
Which of the following drugs is a non-competitive NMDA antagonist and can be used alone or in combination with an anticholinesterase for the treatment of moderate-severe Alzheimer's Disease?
Which of the following drugs is a monoclonal antibody against aggregated amyloid-beta and reduces plaques in a dose- and time-dependent manner?
Which of the following drugs is a monoclonal antibody against aggregated amyloid-beta and reduces plaques in a dose- and time-dependent manner?
Which one of the following opioids is a partial mu agonist and a kappa antagonist?
Which one of the following opioids is a partial mu agonist and a kappa antagonist?
Which opioid is known for its antimuscarinic effects and potential for producing seizures?
Which opioid is known for its antimuscarinic effects and potential for producing seizures?
Which opioid is a weak mu agonist and also inhibits the reuptake of serotonin and norepinephrine?
Which opioid is a weak mu agonist and also inhibits the reuptake of serotonin and norepinephrine?
Which opioid antagonist is usually given intravenously and has a short duration of action?
Which opioid antagonist is usually given intravenously and has a short duration of action?
Which of the following is a characteristic of Parkinsonism?
Which of the following is a characteristic of Parkinsonism?
Which part of the basal ganglia is responsible for motor control and is affected in Parkinson's Disease?
Which part of the basal ganglia is responsible for motor control and is affected in Parkinson's Disease?
Which dopamine pathway is primarily affected in Parkinson's Disease?
Which dopamine pathway is primarily affected in Parkinson's Disease?
What is the role of D2 receptors in the indirect pathway of movement control?
What is the role of D2 receptors in the indirect pathway of movement control?
Which of the following is a side effect of Lecanemab-irmd (Leqembi)?
Which of the following is a side effect of Lecanemab-irmd (Leqembi)?
What is the black box warning for Donanemab?
What is the black box warning for Donanemab?
Which opioid receptor is primarily involved in reward (euphoria) and analgesia?
Which opioid receptor is primarily involved in reward (euphoria) and analgesia?
Which opioid receptor is primarily involved in dysphoria and sedation?
Which opioid receptor is primarily involved in dysphoria and sedation?
Which type of MAO metabolizes NE and 5-HT?
Which type of MAO metabolizes NE and 5-HT?
Which adverse effect is associated with the use of selegiline?
Which adverse effect is associated with the use of selegiline?
What is the mechanism of action of muscarinic receptor antagonists?
What is the mechanism of action of muscarinic receptor antagonists?
What is the recommended initial treatment for mild-to-moderate impairment/early Parkinson's disease?
What is the recommended initial treatment for mild-to-moderate impairment/early Parkinson's disease?
Which of the following strategies can be used to decrease the activation of somatic motor neurons in spasticity?
Which of the following strategies can be used to decrease the activation of somatic motor neurons in spasticity?
Which muscle relaxant acts as a GABAB receptor agonist and decreases the activity of somatic motor neurons both pre- and post-synaptically?
Which muscle relaxant acts as a GABAB receptor agonist and decreases the activity of somatic motor neurons both pre- and post-synaptically?
Which muscle relaxant enhances GABAA receptor activity post-synaptically and provides inhibition of somatic motor neurons?
Which muscle relaxant enhances GABAA receptor activity post-synaptically and provides inhibition of somatic motor neurons?
Which muscle relaxant acts as an alpha2 receptor agonist and is comparable in efficacy to diazepam and baclofen?
Which muscle relaxant acts as an alpha2 receptor agonist and is comparable in efficacy to diazepam and baclofen?
Which centrally acting skeletal muscle relaxant acts primarily in the brain stem, not the spinal cord?
Which centrally acting skeletal muscle relaxant acts primarily in the brain stem, not the spinal cord?
Which local anesthetic preferentially binds and blocks sodium channels in their activated and inactivated states?
Which local anesthetic preferentially binds and blocks sodium channels in their activated and inactivated states?
