3 Questions
What is the main difference between IUGR and SGA?
IUGR implies a pathological process, while SGA is a normal variation
What is the estimated incidence of IUGR if the 5th centile is chosen?
5%
Which of the following is a cause of IUGR?
Cytomegalovirus infection
Study Notes
Definition and Classification of IUGR
- IUGR is defined as the failure of the fetus to achieve its genetic growth potential, resulting in a fetus that is small for gestational age (SGA).
- SGA implies that the fetus or neonate is below a certain defined centile of weight or size for a particular gestational age.
- IUGR indicates a pathological process that modifies the intrinsic growth potential of the fetus, reducing its growth rate.
- The terms SGA and IUGR are not synonymous.
Incidence of IUGR
- The incidence of IUGR is around 3% if the 3rd centile or 5% if the 5th centile is chosen.
Etiology of IUGR
- There are many causes of IUGR, which can be grouped into two main categories.
Factors Affecting Intrinsic Growth Potential
- Chromosomal defects, such as trisomy 18 and triploidy.
- Single-gene effects, such as Seckel's syndrome.
- Structural abnormalities, such as renal agenesis and anencephaly.
- Infections, such as cytomegalovirus, rubella, and protozoal infections like toxoplasmosis.
Learn about intra-uterine growth restriction, a condition where a fetus fails to achieve its genetic growth potential. Understand the differences between IUGR and small for gestational age (SGA).
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