Fetal Complications and Pregnancy Conditions
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Questions and Answers

Which of the following is a characteristic of RBCs in HgB?

  • Microcytic and hypochromic (correct)
  • Microcytic and normochromic
  • Macrocytic and hypochromic
  • Macrocytic and normochromic

    • What is the potential consequence of anemia in a fetus?

  • Erythroid hyperplasia
  • Hepato-splenomegaly
  • Fetal death (correct)
  • Cardio-megaly

    • What is the name of the antibody associated with HgB?

  • HlgB (correct)
  • HlgD
  • HlgA
  • HlgC

    • What is the percentage of HgBart in the blood?

    <p>10%</p> Signup and view all the answers

    What is the name of the antibody associated with Hg portland?

    <p>Hlg portland</p> Signup and view all the answers

    What is the consequence of marked erythroid hyperplasia in a fetus?

    <p>Anemia</p> Signup and view all the answers

    What is the name of the condition characterized by an accumulation of fluid in the abdominal cavity?

    <p>Ascites</p> Signup and view all the answers

    What is the term for the presence of nucleated red blood cells in the blood?

    <p>NRBC</p> Signup and view all the answers

    What is the consequence of cardio-megaly in a fetus?

    <p>Fetal death</p> Signup and view all the answers

    What is the characteristic of RBCs in a fetus with HgB?

    <p>Microcytic and hypochromic</p> Signup and view all the answers

    Study Notes

    Anemia

    • Iron deficiency anemia, chronic inflammation, sideroblastic anemia, and hereditary hemochromatosis are types of anemia.
    • Iron storage, metabolism, and incorporation are related to anemia.

    Hereditary Hemochromatosis

    • Homozygous and heterozygous forms exist.
    • Causes damage.

    Laboratory Diagnosis

    • Tests include evaluation of heme synthesis, free protoporphyrin, serum transferrin receptors, and bone marrow evaluation.

    Sideroblastic Anemia

    • Homozygous and heterozygous hereditary hemochromatosis are causes.
    • Lymphoproliferative neoplasms, such as B-lymphocyte lymphomas, Waldenstrom macroglobulinemia, and chronic lymphocytic leukemia, can cause immune-mediated anemia.

    Thalassemia

    • Beta thalassemia has severe, moderate, and silent forms.
    • Heterozygous individuals are silent carriers.
    • Moderate forms have microcytic and hypochromic RBCs and elevated HbA2 levels.
    • Severe forms have genetic mutations, affecting beta-globin chain production.

    Alpha-Thalassemia

    • Mutations can be large deletions, leading to no alpha-chain production.
    • Silent carriers have a normal hematological profile.
    • Heterozygous individuals have slight decreases in alpha-chain production.
    • Homozygous individuals have a lethal condition due to the absence of alpha-chain production.

    Thalassemia Trait

    • Can be heterozygous or homozygous.
    • Asymptomatic with microcytic and hypochromic RBCs.

    HbH Disease

    • Tetramers of beta-chains accumulate, causing anemia, edema, ascites, and hepatosplenomegaly.
    • Fetal death can occur due to anemia.
    • Adults have balanced beta-chain production, but no HbH.

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    Description

    This quiz covers the complications that can occur during pregnancy, including anemia, edema, and fetal distress. It also explores the effects on the liver, spleen, and cardiovascular system.

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