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Questions and Answers
Which of the following is a characteristic of RBCs in HgB?
Which of the following is a characteristic of RBCs in HgB?
What is the potential consequence of anemia in a fetus?
What is the potential consequence of anemia in a fetus?
What is the name of the antibody associated with HgB?
What is the name of the antibody associated with HgB?
What is the percentage of HgBart in the blood?
What is the percentage of HgBart in the blood?
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What is the name of the antibody associated with Hg portland?
What is the name of the antibody associated with Hg portland?
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What is the consequence of marked erythroid hyperplasia in a fetus?
What is the consequence of marked erythroid hyperplasia in a fetus?
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What is the name of the condition characterized by an accumulation of fluid in the abdominal cavity?
What is the name of the condition characterized by an accumulation of fluid in the abdominal cavity?
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What is the term for the presence of nucleated red blood cells in the blood?
What is the term for the presence of nucleated red blood cells in the blood?
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What is the consequence of cardio-megaly in a fetus?
What is the consequence of cardio-megaly in a fetus?
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What is the characteristic of RBCs in a fetus with HgB?
What is the characteristic of RBCs in a fetus with HgB?
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Study Notes
Anemia
- Iron deficiency anemia, chronic inflammation, sideroblastic anemia, and hereditary hemochromatosis are types of anemia.
- Iron storage, metabolism, and incorporation are related to anemia.
Hereditary Hemochromatosis
- Homozygous and heterozygous forms exist.
- Causes damage.
Laboratory Diagnosis
- Tests include evaluation of heme synthesis, free protoporphyrin, serum transferrin receptors, and bone marrow evaluation.
Sideroblastic Anemia
- Homozygous and heterozygous hereditary hemochromatosis are causes.
B-Cell-Related Disorders
- Lymphoproliferative neoplasms, such as B-lymphocyte lymphomas, Waldenstrom macroglobulinemia, and chronic lymphocytic leukemia, can cause immune-mediated anemia.
Thalassemia
- Beta thalassemia has severe, moderate, and silent forms.
- Heterozygous individuals are silent carriers.
- Moderate forms have microcytic and hypochromic RBCs and elevated HbA2 levels.
- Severe forms have genetic mutations, affecting beta-globin chain production.
Alpha-Thalassemia
- Mutations can be large deletions, leading to no alpha-chain production.
- Silent carriers have a normal hematological profile.
- Heterozygous individuals have slight decreases in alpha-chain production.
- Homozygous individuals have a lethal condition due to the absence of alpha-chain production.
Thalassemia Trait
- Can be heterozygous or homozygous.
- Asymptomatic with microcytic and hypochromic RBCs.
HbH Disease
- Tetramers of beta-chains accumulate, causing anemia, edema, ascites, and hepatosplenomegaly.
- Fetal death can occur due to anemia.
- Adults have balanced beta-chain production, but no HbH.
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Description
This quiz covers the complications that can occur during pregnancy, including anemia, edema, and fetal distress. It also explores the effects on the liver, spleen, and cardiovascular system.
