Isoquinoline Alkaloids: Structure, Types, and Importance

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What is the structural characteristic of isoquinoline and quinoline?

They are composed of a pyridine ring fused to a furan ring
They are benzo pyridines derivatives (correct)
They are composed of two benzene rings
They are composed of two pyridine rings

How many types of Benzylisoquinoline alkaloids are known?

About 200
About 4000 (correct)
About 100
About 1000

What is the common name of the plant from which Ipecac is obtained?

Cephaelis ipecacuanha (correct)
Nicaragua root
Panama plant
Brazilian root

What is the minimum percentage of ethersoluble alkaloids yielded by Ipecac?

2% (C) Signup and view all the answers

Which of the following is an example of a Phenanthrene alkaloid?

morphine (C) Signup and view all the answers

What is the name of the compound that is most important from a biosynthetic point of view?

Reticuline (B) Signup and view all the answers

What is the main effect of tubocurarine on the muscles?

Relaxation of skeletal muscles (D) Signup and view all the answers

What is the active constituent responsible for the antibacterial properties of Barberry?

Berberine (A) Signup and view all the answers

What is the botanical name of the plant from which opium is obtained?

Papaver somniferum (D) Signup and view all the answers

What is the effect of a large dose of tubocurarine chloride on an individual?

Respiratory failure due to muscle paralysis (A) Signup and view all the answers

What is the significance of artificial respiration in individuals administered with tubocurarine chloride?

To prevent respiratory failure (B) Signup and view all the answers

What is the term 'opium' derived from?

Greek word for poppy juice (B) Signup and view all the answers

What is the intermediate with a phenanthrene nucleus formed in the biosynthetic pathway starting with nor laudanosoline?

Salutaridine (A) Signup and view all the answers

What is the result of stepwise demethylation of thebaine?

Formation of morphine and codeine (A) Signup and view all the answers

What is the significance of P.bracteatum in biosynthetic studies?

It lacks demethylation capability (C) Signup and view all the answers

Why is thebaine useful commercially?

It can be converted to codeine (C) Signup and view all the answers

What is the therapeutic significance of P.somniferum?

It produces morphine (C) Signup and view all the answers

What distinguishes useful plants from those of only scientific interest?

Subtle metabolic differences (D) Signup and view all the answers

What is Sanguinaria composed of?

Dried rhizomes and roots of Sanguinaria canadensis (B) Signup and view all the answers

What is the effect of sanguinarine on chromosomes in a cell?

It causes doubling of the chromosomes (B) Signup and view all the answers

What is the biosynthetic precursor of isoquinoline alkaloids?

Phenylalanine and tyrosine (B) Signup and view all the answers

What is the function of Sanguinaria in pharmaceuticals?

It is used as an ingredient in compound white pine syrup (C) Signup and view all the answers

What is the intermediate in the biosynthesis of papaverine?

Norlaudanosoline (C) Signup and view all the answers

What is the biosynthetic precursor of morphine?

Two molecules of tyrosine (C) Signup and view all the answers

Which international organization controls the cultivation of opium poppy?

International Narcotic Control Board of the United Nations (B) Signup and view all the answers

Isoquinoline Alkaloids: Structure, Types, and Importance

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