Podcast
Questions and Answers
What is Ischemic Heart Disease?
What is Ischemic Heart Disease?
What are the four closely related conditions/syndromes that come under Ischemic Heart Disease?
What are the four closely related conditions/syndromes that come under Ischemic Heart Disease?
Why does the heart muscle need a constant supply of oxygen?
Why does the heart muscle need a constant supply of oxygen?
What can happen if myocardial ischemia persists?
What can happen if myocardial ischemia persists?
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What is a coronary artery anomaly?
What is a coronary artery anomaly?
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What is coronary artery spasm?
What is coronary artery spasm?
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What can trigger coronary artery spasm?
What can trigger coronary artery spasm?
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What is the main cause of Ischemic Heart Disease?
What is the main cause of Ischemic Heart Disease?
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What percentage of vessel lumen obstruction is generally considered critical stenosis?
What percentage of vessel lumen obstruction is generally considered critical stenosis?
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What is the primary cause of unstable angina and infarction?
What is the primary cause of unstable angina and infarction?
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What is a major risk factor for developing angina?
What is a major risk factor for developing angina?
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What is the effect of smoking on the heart?
What is the effect of smoking on the heart?
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What is the effect of high blood pressure on the arteries?
What is the effect of high blood pressure on the arteries?
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Where is angina typically located?
Where is angina typically located?
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What is the effect of high cholesterol levels on the heart?
What is the effect of high cholesterol levels on the heart?
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What is a common trigger for angina pain?
What is a common trigger for angina pain?
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What is the effect of diabetes on blood vessels?
What is the effect of diabetes on blood vessels?
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What is a key difference between angina and indigestion or heartburn?
What is a key difference between angina and indigestion or heartburn?
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What is the benefit of regular exercise on the heart?
What is the benefit of regular exercise on the heart?
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What is a non-modifiable risk factor for angina?
What is a non-modifiable risk factor for angina?
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Why are men more susceptible to angina?
Why are men more susceptible to angina?
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What happens to the risk of angina in women after menopause?
What happens to the risk of angina in women after menopause?
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What is T-wave inversion an abnormal change in?
What is T-wave inversion an abnormal change in?
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What is the primary goal of managing angina?
What is the primary goal of managing angina?
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What type of medication is prescribed to reduce the risk of blood clots forming?
What type of medication is prescribed to reduce the risk of blood clots forming?
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What is the function of Nitroglycerin?
What is the function of Nitroglycerin?
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What is the purpose of Statin medications?
What is the purpose of Statin medications?
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What is Percutaneous Coronary Intervention (PCI) commonly known as?
What is Percutaneous Coronary Intervention (PCI) commonly known as?
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What is the purpose of Coronary Artery Bypass Grafting (CABG)?
What is the purpose of Coronary Artery Bypass Grafting (CABG)?
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What is Cardiac Rehabilitation?
What is Cardiac Rehabilitation?
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What type of imaging test uses sound waves to create images of the heart?
What type of imaging test uses sound waves to create images of the heart?
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Which test involves injecting a radioactive tracer into the bloodstream?
Which test involves injecting a radioactive tracer into the bloodstream?
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What is the purpose of a Cardiac CT Scan?
What is the purpose of a Cardiac CT Scan?
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What is the significance of ST-segment depression on an ECG?
What is the significance of ST-segment depression on an ECG?
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Which test is considered the gold standard for diagnosing significant coronary artery disease?
Which test is considered the gold standard for diagnosing significant coronary artery disease?
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What is the purpose of injecting a contrast dye into the coronary arteries during Coronary Angiography?
What is the purpose of injecting a contrast dye into the coronary arteries during Coronary Angiography?
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What is the characteristic change seen on an ECG during an angina episode?
What is the characteristic change seen on an ECG during an angina episode?
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What is the purpose of an Echocardiogram?
What is the purpose of an Echocardiogram?
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Study Notes
Ischemic Heart Disease
- Ischemic heart disease (IHD) occurs when there is an imbalance between myocardial oxygen supply and demand, leading to myocardial hypoxia and accumulation of waste metabolites.
- Atherosclerosis of the coronary arteries is the most common cause of IHD.
- Four closely related conditions/syndromes that come under IHD are:
- Angina (stable and unstable)
- Acute myocardial infarction (MI)
- Heart failure
- Sudden cardiac death
Causes of Myocardial Ischemia
- Atherosclerotic causes of ischemia:
- Atherosclerosis of the coronary arteries
- Non-atherosclerotic causes of ischemia:
- Coronary artery anomalies (e.g., narrowing, abnormal origin or course of the arteries, or fistulas)
- Coronary artery spasm (temporary narrowing of the coronary arteries caused by a sudden contraction of the muscles in the arterial walls)
Angina Pectoris
- Angina is a condition in which there is a temporary reduction in blood flow to the heart muscle, leading to chest pain or discomfort.
- Angina can be stable (predictable and triggered by physical exertion) or unstable (unpredictable and triggered by emotional stress or other factors).
- Symptoms of angina:
- Chest pain or discomfort (usually located behind the breastbone, but can radiate to the neck, jaw, shoulders, arms, or back)
- Shortness of breath (especially during episodes of chest pain)
- Fatigue (particularly during or after physical activity or stressful situations)
- Indigestion or heartburn (in some cases, angina can be mistaken for indigestion or heartburn)
Risk Factors for Angina Pectoris
- Non-modifiable risk factors:
- Age (especially for men over 45 and women over 55)
- Family history (having a close relative with coronary artery disease)
- Sex (men are generally more susceptible to angina than pre-menopausal women)
- Modifiable risk factors:
- Smoking
- High blood pressure (hypertension)
- High cholesterol levels
- Diabetes
- Obesity
- Sedentary lifestyle
- Stress
Diagnosis of Angina Pectoris
- Imaging tests:
- Echocardiogram (ultrasound test that uses sound waves to create images of the heart)
- Nuclear stress test (uses a radioactive tracer to highlight areas of the heart with reduced blood flow)
- Cardiac CT scan (uses computed tomography to produce detailed images of the heart and its blood vessels)
- Coronary angiography (invasive procedure that involves injecting a contrast dye into the coronary arteries, followed by X-ray imaging)
Management of Angina Pectoris
- Lifestyle modifications:
- Smoking cessation
- Healthy diet
- Regular exercise and weight management
- Pharmacological management:
- Antiplatelet agents (e.g., aspirin or clopidogrel)
- Nitroglycerin
- Beta-blockers
- Calcium channel blockers
- Statins
- Procedures and interventions:
- Percutaneous coronary intervention (PCI) (also known as angioplasty)
- Coronary artery bypass grafting (CABG)
- Cardiac rehabilitation (programs that offer supervised exercise, education, and counseling)
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Description
Learn about the pathophysiology of Coronary Artery Disease (CAD) and its effects on the myocardium. Understand the imbalance between myocardial oxygen supply and demand.