5 Questions
What is the term for receptors that gate ion channels indirectly?
Metabotropic receptors
What type of receptor is the nicotinic ACh receptor at the neuromuscular junction?
Ionotropic receptor
How do ionotropic receptors respond to neurotransmitter binding?
By opening the ion channel
What process integrates competing inputs in the postsynaptic neuron?
Synaptic transmission
What prevents the firing of action potentials in the postsynaptic neuron?
$\gamma$-aminobutyric acid (GABA) receptor activation
Study Notes
Receptors and Ion Channels
- Metabotropic receptors are the term for receptors that gate ion channels indirectly.
- The nicotinic ACh receptor at the neuromuscular junction is an example of an ionotropic receptor.
Ionotropic Receptors
- Ionotropic receptors respond to neurotransmitter binding by directly opening or closing ion channels.
Integration of Competing Inputs
- The process of integration of competing inputs in the postsynaptic neuron is known as synaptic integration.
Regulation of Action Potential Firing
- Inhibition prevents the firing of action potentials in the postsynaptic neuron.
Test your knowledge about the different types of receptors that gate ion channels directly and indirectly in the nervous system. Understand the conformational changes and mechanisms involved in neurotransmitter binding and channel opening.
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