Investigating Nutritional Anaemias

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Questions and Answers

What is the primary role of haematinics in the body?

  • To facilitate muscle contraction
  • To enhance nerve function
  • To provide energy for cellular respiration
  • To assist in the production of blood cells (correct)

Which of the following is NOT considered a haematinic?

  • Iron
  • Folate (B9)
  • Vitamin D (correct)
  • Cobalamin (B12)

When might haematinic measurements typically be requested?

  • To investigate nutritional anaemias (correct)
  • To assess bone density
  • To evaluate kidney performance
  • To monitor liver function

What is a potential shortcoming of haematinic measurements?

<p>They may lack necessary sensitivity and specificity (C)</p> Signup and view all the answers

Which of the following nutrients is involved in the absorption of iron?

<p>Vitamin C (A)</p> Signup and view all the answers

What type of blood picture is typically associated with nutritional anaemias?

<p>Microcytic or macrocytic (B)</p> Signup and view all the answers

Which two vitamins are most commonly associated with nutritional anaemias?

<p>B12 (Cobalamin) and Folate (B9) (C)</p> Signup and view all the answers

What additional tests may be requested alongside haematinic measurements to aid in diagnosis?

<p>Full blood count (FBC) and blood cell morphology (A)</p> Signup and view all the answers

Which component is essential in the transport of iron in the blood?

<p>Transferrin (A)</p> Signup and view all the answers

What can haematinic measurements promote in the body when administered?

<p>Reticulocyte response and increase in haemoglobin concentration (B)</p> Signup and view all the answers

Flashcards

Haematinics

Nutrients essential for the production of blood cells in the bone marrow.

Iron

Iron is a crucial haematinic involved in the synthesis of haemoglobin, the oxygen-carrying protein in red blood cells.

Ferritin

A protein that stores iron in the body, providing an indicator of iron stores.

Transferrin

A protein in blood that binds and transports iron throughout the body.

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Transferrin Saturation

The percentage of transferrin that is saturated with iron, indicating the body's ability to transport iron efficiently.

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Cobalamin (B12)

A vitamin essential for DNA synthesis, crucial for the production of red blood cells.

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Folate (B9)

A vitamin essential for DNA synthesis, crucial for the production of red blood cells.

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Haematinic Measurements

Blood tests that measure levels of haematinics, such as iron, vitamin B12, and folate.

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Nutritional Anaemias

Anaemias caused by deficiencies of specific nutrients, often affecting the size and shape of red blood cells.

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Reticulocyte Response

A response to haematinic therapy, characterized by an increase in immature red blood cells (reticulocytes), indicating improved red blood cell production.

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Study Notes

Investigating Nutritional Anaemias

  • Nutritional anaemia results from deficiencies in nutrients essential for blood cell production.
  • Haematinics are nutrients needed by the haematopoietic tissue to produce blood cells.
  • Common haematinics include iron, vitamin B12 (cobalamin), and folate.
  • Iron measurements include ferritin, transferrin, and transferrin saturation.
  • Cobalamin is also known as vitamin B12.
  • Folate, also known as vitamin B9.
  • Other B vitamins (B2, B3, B6) are also involved.
  • Vitamin A, Vitamin C, Vitamin E, Copper (through Hephaestin and ceruloplasmin), and Cobalt are also considered essential in blood cell production.
  • Haematinic measurements help identify nutritional anaemias. However, these measurements can lack the sensitivity and specificity for a definitive diagnosis.
  • Additional tests are often required to confirm diagnosis.
  • Complete Blood Count (FBC) and blood cell morphology are important considerations before haematinic measurements.
  • Haematinic treatments can promote reticulocyte response, increase haemoglobin concentrations, resolve cytopenias, and correct/partially correct clinically relevant symptoms.
  • Nutritional anaemias are often associated with microcytic or macrocytic blood pictures, although this isn't always the case.
  • Haematinic measurements may be performed in haematology or biochemistry laboratories, depending on the lab's structure.

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