Introduction to Sleep Regulation and ipRGCs
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Questions and Answers

What role do REM neurons play in promoting REM sleep?

  • Producing atonia seen in dreaming sleep
  • Contributing to EEG desynchronization (correct)
  • Exciting Action neurons
  • Inhibiting Arousal neurons

How do REM neurons interact with Action neurons?

  • REM neurons inhibit Action neurons (correct)
  • They excite each other
  • They have no interaction
  • They both promote atonia in dreaming sleep

Which condition is characterized by an urge to sleep during the day?

  • Cataplexy
  • Insomnia
  • Narcolepsy (correct)
  • Sleep paralysis

What symptom is associated with cataplexy in narcolepsy?

<p>Loss of muscle control during waking hours (B)</p> Signup and view all the answers

What may be a cause of sleep disorders like insomnia according to the text?

<p>Gross underestimation of the amount of sleep actually obtained (D)</p> Signup and view all the answers

Which phenomenon is associated with REM sleep behavior disorder?

<p>Inhibition of normal paralysis during sleep (A)</p> Signup and view all the answers

What type of retinal cells are responsible for conveying irradiance information centrally via the optic nerve?

<p>ipRGCs (D)</p> Signup and view all the answers

Which part of the brain is primarily responsible for releasing melatonin in response to light information from the ipRGCs?

<p>Suprachiasmatic nucleus (SCN) (A)</p> Signup and view all the answers

What is responsible for the decrease in melatonin secretion as age increases?

<p>Melanopsin (D)</p> Signup and view all the answers

Which type of brain waves are characteristic of being awake?

<p>High amplitude, high frequency, irregular (A)</p> Signup and view all the answers

In what order do the waves signaling the beginning of a dream episode travel through the brain?

<p>LGN of thalamus → Pons → Occipital lobe (A)</p> Signup and view all the answers

What area of the brain is responsible for differentiating between activating and sleep states?

<p>Pons (B)</p> Signup and view all the answers

What neurotransmitter is associated with the basal forebrain?

<p>Acetylcholine (C)</p> Signup and view all the answers

What effect does electrical stimulation of the basal forebrain produce?

<p>Wakefulness (A)</p> Signup and view all the answers

Which area, when turned off, synchronizes the EEG?

<p>Basal forebrain (B)</p> Signup and view all the answers

During which sleep stage do orexin/hypocretin cell bodies in the lateral hypothalamus have low activity?

<p>Slow wave sleep (A)</p> Signup and view all the answers

What is the role of noradrenergic neurons in the locus coeruleus during sleep?

<p>Inhibit movement during sleep (B)</p> Signup and view all the answers

Which neurons actively promote NREM sleep and inhibit Action and Arousal neurons?

<p>NREM neurons (B)</p> Signup and view all the answers

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