Introduction to Physical Pharmacy
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Questions and Answers

What does physical pharmacy primarily focus on?

  • Development of new medicinal compounds
  • Patient counseling and education
  • The application of biological sciences in pharmacy
  • Quantitative and theoretical principles of physicochemical science (correct)

Which statement correctly defines a dosage form?

  • An entity administered to patients to provide an effective dose of a drug (correct)
  • A pre-formed liquid solution of a drug
  • The mathematical calculation of medication doses
  • The theoretical framework for drug formulation

What is true about significant figures?

  • Zeros between non-zero digits are never significant
  • Leading zeros in a number are always significant
  • All non-zero digits are significant (correct)
  • Zeros at the end of a number are never significant

How is pressure defined in scientific terms?

<p>The force exerted per unit area (D)</p> Signup and view all the answers

Which of the following is the standard unit of volume in the cgs system?

<p>Cubic centimeter (D)</p> Signup and view all the answers

What defines density in terms of mass and volume?

<p>Mass per unit volume at fixed temperature and pressure (B)</p> Signup and view all the answers

How is specific gravity determined?

<p>By measuring the weight of a substance against the weight of an equal volume of water (C)</p> Signup and view all the answers

Which of the following describes accuracy in measurements?

<p>The degree to which results reflect the true value (C)</p> Signup and view all the answers

What is indicated by the standard deviation in a data set?

<p>The average of the deviations from the mean (C)</p> Signup and view all the answers

Which type of error is classified as constant and can be corrected once identified?

<p>Determinate error (B)</p> Signup and view all the answers

Flashcards

Physical Pharmacy

Applies physicochemical principles to pharmacy practice

Dosage Form

The physical form of a drug for administration.

Density

Mass per unit volume.

Specific Gravity

Weight compared to equal volume of a standard substance.

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Determinate Errors

Correctable, predictable errors.

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Indeterminate Errors

Random errors from chance.

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Precision

Agreement between repeated measurements.

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Accuracy

Agreement between measurement and true value.

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Standard Deviation

Average difference from the mean.

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Significant Figures

Rules for expressing measured values.

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Study Notes

Learning Outcomes

  • Define key terms related to physical pharmacy and pharmaceutical science.
  • Understand rules for significant figures.
  • Explain statistical methods and analyze errors in measurements.

Terminologies

  • Physical Pharmacy: Integrates physicochemical principles into pharmacy practice.
  • Pharmaceutical Science: Focuses on the biomedical aspects of pharmacy.
  • Dosage Form: The physical form in which a drug is administered to ensure effective dosing.

Key Measurements

  • Volume: Measured in cubic meters; 1 cubic meter = 1,000,000 cubic centimeters.
  • Mass: Standard unit is kilograms, defined by a platinum-iridium block.
  • Force: A push or pull; influenced by mass and acceleration.
  • Pressure: Force per unit area; commonly expressed in dyne/cm².
  • Work and Energy: Energy enables work; classified as kinetic or potential energy.
  • Temperature: 0°C = 273.15K.

Density and Specific Gravity

  • Density: Mass per unit volume; expressed as grams per cubic centimeter (g/cm³).
  • Specific Gravity: Weight of a substance compared to an equal volume of a standard substance.

Sample Calculations

  • Determine the weight of 300 mL of alcohol with a specific gravity of 0.8.
  • Calculate the volume in milliliters of 900g of glycerine with a specific gravity of 1.25.

Statistical Methods and Error Analysis

  • Determinate Errors: Correctable, predictable errors that can often be avoided.
  • Indeterminate Errors: Random pattern of errors resulting from chance; average value termed the mean.
  • Pseudoaccidental Errors: Result from fluctuations in external factors; manageable through technique refinement.

Precision and Accuracy

  • Precision: Degree of agreement among a set of values.
  • Accuracy: Agreement between data and the true value of a measurement.

Measures of Dispersion

  • Variability: Assessed through range, mean, and standard deviation.
  • Range: Difference between the highest and lowest values in a dataset.
  • Standard Deviation: Represents average deviation from the mean; useful for understanding data distribution.
  • Coefficient of Variation: Percentage measure useful for comparing variability across datasets.

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Description

This quiz covers essential concepts in Physical Pharmacy, including definitions, significant figures, and statistical methods. It aims to assess students' understanding of key terminologies and rules within pharmaceutical science. Prepare to explore important principles that form the foundation of physical pharmacy.

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