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Introduction to Pharmacology: Medication Development

10 Questions

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Introduction to Pharmacology: Medication Development

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Questions and Answers

What is the phase of clinical development where the medication is compared to the standard treatment in a large group size?

Phase 2

Phase 4

Phase 3 (correct)

Phase 1

Which type of medication name is used by health professionals?

Brand Name

Generic Name (correct)

Chemical Name

Common Name

What does the Therapeutic Index (TI) measure?

Ratio of Medication Interactions to Side Effects

Ratio of Metabolism to Excretion of medication

Ratio of Absorption to Distribution of medication

Ratio of Toxic Dose to Effective Dose of medication (correct)

Which type of medication interaction alters the absorption, distribution, metabolism, and excretion of another drug?

Pharmacokinetic Interaction Signup and view all the answers

What does ADME stand for in pharmacokinetics?

Absorption, Distribution, Metabolism, Excretion Signup and view all the answers

What is the role of enzymes in biochemical reactions?

To function as catalysts and speed up reactions Signup and view all the answers

What does a high Km value indicate about enzyme affinity for a substrate?

Low enzyme affinity for substrate Signup and view all the answers

In pharmacodynamics, what is the function of G-Protein Coupled Receptors?

Activate G-Proteins to start a signal transduction cascade Signup and view all the answers

Which characteristic is associated with medications having high potency?

High affinity for receptors and require less medication to produce effect Signup and view all the answers

What type of curve is observed in the dose-response relationship of medications?

Sigmoidal (S-shaped) curve Signup and view all the answers