Introduction to Pharmacology: Medication Development

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10 Questions

What is the phase of clinical development where the medication is compared to the standard treatment in a large group size?

Phase 3

Which type of medication name is used by health professionals?

Generic Name

What does the Therapeutic Index (TI) measure?

Ratio of Toxic Dose to Effective Dose of medication

Which type of medication interaction alters the absorption, distribution, metabolism, and excretion of another drug?

Pharmacokinetic Interaction

What does ADME stand for in pharmacokinetics?

Absorption, Distribution, Metabolism, Excretion

What is the role of enzymes in biochemical reactions?

To function as catalysts and speed up reactions

What does a high Km value indicate about enzyme affinity for a substrate?

Low enzyme affinity for substrate

In pharmacodynamics, what is the function of G-Protein Coupled Receptors?

Activate G-Proteins to start a signal transduction cascade

Which characteristic is associated with medications having high potency?

High affinity for receptors and require less medication to produce effect

What type of curve is observed in the dose-response relationship of medications?

Sigmoidal (S-shaped) curve

Learn about the study of medications and how they interact with living systems, including the development stages of medications from discovery to clinical trials, focusing on safety, efficacy, approval, and long-term effects.

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