Introduction to Pharmacology: Definition and Basics

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20 Questions

Where does the majority of drug absorption take place due to the anatomical structure?

Small intestine

What is the principal site of drug metabolism?

Liver

What is the study of substances used to prevent, diagnose, and treat disease called?

Medical pharmacology

What is the process by which drugs diffuse or are transferred from intravascular space to extravascular space called?

Distribution

What is the relation of the individual’s genetic makeup to his or her response to specific drugs called?

Pharmacogenomics

What is the definition of pharmacology?

The study of substances that interact with living systems through chemical processes

How can drugs be obtained?

Through synthetic chemicals, plants, animals, or genetic engineering

Which statement best defines a drug?

A substance that brings about a change in biologic function through its chemical actions

What is the process of altering the DNA in an organism’s genome known as?

Genetic engineering

Which term refers to a chemical substance of known structure that produces a biological effect when administered to a living organism?

Drug

Which route of drug administration is considered the safest, most common, convenient, and economical method?

Oral administration

Where do most drugs absorbed from the gastrointestinal (GI) tract enter before they are distributed into the general circulation?

Liver

What is the major site for drug absorption due to its larger absorptive surface in the alimentary canal?

Duodenum

Which route of drug administration has pathways involved in absorption considered the most complicated?

Oral administration

What is the process that some drugs undergo in the liver, where they may be extensively metabolized before entering the systemic circulation?

First-pass metabolism

What is the advantage of using the rectal route for drug administration?

Prevents destruction of the drug in the gastrointestinal environment

Why is parenteral administration used for certain drugs?

To introduce drugs directly into the systemic circulation for drugs that are poorly absorbed from the GI tract

Which route of administration is effective and convenient for patients with respiratory disorders?

Oral inhalation

What is the advantage of using intrathecal/intraventricular routes of drug administration?

Introduces drugs directly into the cerebrospinal fluid

Why are drugs that are gases administered via inhalation?

To provide rapid delivery of the drug across the large surface area of the respiratory tract

This quiz covers the fundamental concepts of pharmacology, including the definition of pharmacology and drugs, their chemical actions, and their impact on biologic functions. Explore the study of substances that interact with living systems and their role in activating or inhibiting normal body processes.

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