Introduction to Molecular Biology and DNA History

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Questions and Answers

What is the genotype of an organism?

  • The genes that control the trait of interest (correct)
  • A segment of a DNA molecule corresponding to a unit of inheritance
  • The sum of all the DNA in one set of chromosomes
  • The observable physical or behavioral traits of a cell or organism

In which year did Watson & Crick propose the molecular model of DNA structure?

  • 1977
  • 1953 (correct)
  • 1983
  • 1944

What are the simple units of the DNA polymer called?

  • Nucleotides (correct)
  • Gene products
  • Phosphate groups
  • Deoxyribose

Who developed a procedure for gene isolation in 1978?

<p>Maniatis et al. (A)</p> Signup and view all the answers

What does the backbone of the DNA strands consist of?

<p>Sugars (deoxyribose) and phosphate groups (A)</p> Signup and view all the answers

Who described lab methods for DNA sequencing in 1977?

<p>Maxam &amp; Gilbert (C)</p> Signup and view all the answers

What is the sum of all the genes in one set of chromosomes known as?

<p>Genome of an organism (narrow sense) (B)</p> Signup and view all the answers

Who invented the technique known as the polymerase chain reaction (PCR) in 1983?

<p>Mullis (A)</p> Signup and view all the answers

What is the phenotype of an organism determined by?

<p>The organism's genotype and environment jointly (D)</p> Signup and view all the answers

What percentage of the human genome consists of genes and related sequences?

<p>30% (D)</p> Signup and view all the answers

What is DNA usually existing as in living organisms?

<p>Double helix (B)</p> Signup and view all the answers

Which DNA region is responsible for the termination of transcription?

<p>Termination signal (A)</p> Signup and view all the answers

What is the process called that includes transcription (DNA to mRNA) and translation (mRNA to protein)?

<p>Gene expression (C)</p> Signup and view all the answers

In the genes, which DNA regions are responsible for coding and non-coding sequences?

<p>Exons and introns (D)</p> Signup and view all the answers

What is the percentage of the human genome that consists of non-coding regions like introns and pseudogenes?

<p>10% (B)</p> Signup and view all the answers

What is the name of the DNA region that contains the coding sequence?

<p>Structure gene (D)</p> Signup and view all the answers

Which DNA/RNA is able to encode proteins based on the genetic code?

<p>Codons (D)</p> Signup and view all the answers

What DNA fragments are continuous?

<p>Genes (D)</p> Signup and view all the answers

What is the term for slight variations on the standard genetic code, such as in vertebrate mitochondria?

<p>&quot;Redundant, degenerated but unambiguous&quot; (B)</p> Signup and view all the answers

What runs side by side in prokaryotes vs. eukaryotes?

<p>Transcription and translation (C)</p> Signup and view all the answers

What is the name of the DNA region responsible for binding the RNA polymerase and initiating transcription?

<p>Promoter (C)</p> Signup and view all the answers

Which of the following is a type of nucleotide found in DNA?

<p>dCTP (D)</p> Signup and view all the answers

What did Maxam & Gilbert, as well as Sanger et al., describe in 1977?

<p>Lab methods for DNA sequencing (A)</p> Signup and view all the answers

What is the term for a slight variation on the standard genetic code found in vertebrate mitochondria?

<p>Mitochondrial codon reassignment (C)</p> Signup and view all the answers

What is the term for the sum of all the DNA in one set of chromosomes in the broad sense?

<p>Genome (C)</p> Signup and view all the answers

In eukaryotes, what is the backbone of the DNA strands made of?

<p>Deoxyribose and phosphate groups (D)</p> Signup and view all the answers

Who developed a procedure for gene isolation in 1978?

<p>Maniatis et al. (C)</p> Signup and view all the answers

What are the simple units of the DNA polymer called?

<p>Nucleotides (D)</p> Signup and view all the answers

What is the term for the sum of all the genes in one set of chromosomes in the narrow sense?

<p>'Expressed' genome (B)</p> Signup and view all the answers

Which DNA region contains the coding sequence for a gene?

<p>Exon (C)</p> Signup and view all the answers

What percentage of the human genome consists of genes and related sequences?

<p>2% (C)</p> Signup and view all the answers

What percentage of the human genome consists of non-coding regions like introns and pseudogenes?

<p>25% (B)</p> Signup and view all the answers

In the genes, which DNA regions are responsible for coding and non-coding sequences?

<p>Exons and introns (C)</p> Signup and view all the answers

In eukaryotes, what is the backbone of the DNA strands made of?

<p>Phosphate groups (D)</p> Signup and view all the answers

What is the genotype of an organism?

<p>Genetic makeup of an organism (C)</p> Signup and view all the answers

What did Maxam & Gilbert, as well as Sanger et al., describe in 1977?

<p>DNA sequencing methods (B)</p> Signup and view all the answers

What is the name of the DNA region responsible for binding the RNA polymerase and initiating transcription?

<p>Promoter (A)</p> Signup and view all the answers

What DNA fragments are continuous?

<p>Exons (D)</p> Signup and view all the answers

What is the term for the sum of all the genes in one set of chromosomes in the narrow sense?

<p>Exon (D)</p> Signup and view all the answers

Which DNA region contains the coding sequence for a gene?

<p>Exon (C)</p> Signup and view all the answers

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