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Questions and Answers
What is the primary function of fibrinogen in the process of hemostasis?
What is the primary function of fibrinogen in the process of hemostasis?
- Fibrinogen constricts blood vessels to reduce blood flow
- Fibrinogen serves as an enzyme to activate the coagulation cascade
- Fibrinogen promotes platelet adherence to the blood vessel wall
- Fibrinogen is converted to fibrin, which acts as the glue to stop bleeding (correct)
Which phase of hemostasis involves the formation of an insoluble fibrin clot?
Which phase of hemostasis involves the formation of an insoluble fibrin clot?
- Primary hemostasis
- Platelet aggregation
- Platelet plug formation
- Secondary hemostasis (correct)
What is the main cause of thrombosis?
What is the main cause of thrombosis?
- Platelet adherence to the blood vessel wall
- Constriction of blood vessels
- Formation of a platelet plug
- Formation of a clot in a blood vessel (correct)
What is the role of vasoconstriction in the process of hemostasis?
What is the role of vasoconstriction in the process of hemostasis?
Which component is responsible for the continual process of fibrin digestion by plasmin?
Which component is responsible for the continual process of fibrin digestion by plasmin?
What is the role of heparin sulfate in the blood vessel?
What is the role of heparin sulfate in the blood vessel?
Which part of the blood vessel contains tissue factor that activates coagulation and fibrin formation?
Which part of the blood vessel contains tissue factor that activates coagulation and fibrin formation?
What is the primary function of platelets during the stoppage of bleeding?
What is the primary function of platelets during the stoppage of bleeding?
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Study Notes
Hemostasis Process
- Fibrinogen plays a primary role in hemostasis by converting into fibrin, which forms a clot to stop bleeding.
Phases of Hemostasis
- The coagulation phase involves the formation of an insoluble fibrin clot, which is essential for hemostasis.
Thrombosis
- The main cause of thrombosis is the formation of a blood clot (thrombus) inside a blood vessel, which can obstruct blood flow.
Vasoconstriction
- Vasoconstriction plays a crucial role in hemostasis by reducing blood flow to the injured area, thereby minimizing blood loss.
Fibrin Digestion
- Plasmin is responsible for the continual process of fibrin digestion, which helps to dissolve blood clots.
Heparin Sulfate
- Heparin sulfate, present in the blood vessel, inhibits thrombin and prevents excessive blood clotting.
Tissue Factor
- The endothelium, the innermost layer of the blood vessel, contains tissue factor that activates coagulation and fibrin formation.
Platelet Function
- The primary function of platelets during the stoppage of bleeding is to form a platelet plug, which is reinforced by fibrin to create a stable clot.
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