Hemodynamics II

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Which of the following is NOT a component of normal hemostasis?

Platelets

Counter-regulation (correct)

Coagulation cascade

Vascular wall

What is the primary function of endothelial cells in a healthy blood vessel?

Promotion of coagulation cascade

Promotion of platelet adherence

Inhibition of platelets (correct)

Inhibition of coagulation

What are the causes of pathological thrombosis?

Endothelial injury

Abnormal flow

Hypercoagulability of blood

All of the above (correct)

Which type of thrombus forms in the heart?

Cardiac (mural) thrombus Signup and view all the answers

What are the 4 steps in the formation and regulation of the permanent hemostatic plug?

Local response, primary hemostatic plug, secondary hemostatic plug, counter-regulation Signup and view all the answers

Which of the following factors is responsible for the activation of Factor X in the extrinsic pathway of the coagulation cascade?

Factor VII Signup and view all the answers

Which of the following factors is responsible for the activation of Factor IX in the intrinsic pathway of the coagulation cascade?

Factor XI Signup and view all the answers

Which of the following factors is responsible for the activation of Factor X in the intrinsic pathway of the coagulation cascade?

Factor IX Signup and view all the answers

Which of the following factors is responsible for the conversion of prothrombin to active thrombin in the common pathway of the coagulation cascade?

Factor V Signup and view all the answers

Which of the following factors is responsible for the conversion of fibrinogen to fibrin in the final clot formation?

Factor XIII Signup and view all the answers

Which of the following is the main cause of arterial thrombus formation?

Endothelial damage Signup and view all the answers

Which of the following is NOT a characteristic of venous thrombi?

Elongation in the direction of blood flow Signup and view all the answers

What is the fate of a thrombus?

Propagation, fibrinolytic resolution, embolization, organization Signup and view all the answers

What is the main cause of disseminated intravascular coagulation (DIC)?

All of the above Signup and view all the answers

What is the consequence of disseminated intravascular coagulation (DIC)?

Uncontrolled bleeding disorder Signup and view all the answers

Which of the following is NOT one of the causes of pathological thrombosis according to the Virchow triad?

Increased platelet count Signup and view all the answers

What is the characteristic of a mural thrombus in the heart?

Lines of Zahn Signup and view all the answers

Which genetic defect causes resistance to inhibition by Protein C?

Factor V mutation Signup and view all the answers

Which of the following is an acquired cause of hypercoagulability?

Heparin-induced thrombocytopenia syndrome Signup and view all the answers

What is the role of tissue factor pathway inhibitor (TFPI) in hemostasis?

Inhibits the factor X and VII complex Signup and view all the answers

Which of the following is NOT a component of normal hemostasis?

Fibrinolysis Signup and view all the answers

Which step in the hemostatic response to vascular injury involves the activation of the coagulation cascade?

Formation of secondary hemostatic plug Signup and view all the answers

What is the role of thrombin in the formation of the secondary hemostatic plug?

Thrombin cleaves fibrinogen to insoluble fibrin Signup and view all the answers

What is the purpose of counterregulatory measures in the hemostatic process?

To prevent thrombus formation Signup and view all the answers

What is the role of endothelial cells in hemostasis in a normal cell?

To inhibit coagulation Signup and view all the answers

Which of the following is NOT a way in which endothelial cells inhibit thrombus formation in a normal vessel?

Binding anti-thrombin III Signup and view all the answers

Which of the following is NOT a function of endothelial cells in inhibiting coagulation?

Activating Protein C Signup and view all the answers

Hemodynamics II

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Questions and Answers

Which of the following is NOT a component of normal hemostasis?

What is the primary function of endothelial cells in a healthy blood vessel?

What are the causes of pathological thrombosis?

Which type of thrombus forms in the heart?

What are the 4 steps in the formation and regulation of the permanent hemostatic plug?

Which of the following factors is responsible for the activation of Factor X in the extrinsic pathway of the coagulation cascade?

Which of the following factors is responsible for the activation of Factor IX in the intrinsic pathway of the coagulation cascade?

Which of the following factors is responsible for the activation of Factor X in the intrinsic pathway of the coagulation cascade?

Which of the following factors is responsible for the conversion of prothrombin to active thrombin in the common pathway of the coagulation cascade?

Which of the following factors is responsible for the conversion of fibrinogen to fibrin in the final clot formation?

Which of the following is the main cause of arterial thrombus formation?

Which of the following is NOT a characteristic of venous thrombi?

What is the fate of a thrombus?

What is the main cause of disseminated intravascular coagulation (DIC)?

What is the consequence of disseminated intravascular coagulation (DIC)?

Which of the following is NOT one of the causes of pathological thrombosis according to the Virchow triad?

What is the characteristic of a mural thrombus in the heart?

Which genetic defect causes resistance to inhibition by Protein C?

Which of the following is an acquired cause of hypercoagulability?

What is the role of tissue factor pathway inhibitor (TFPI) in hemostasis?

Which of the following is NOT a component of normal hemostasis?

Which step in the hemostatic response to vascular injury involves the activation of the coagulation cascade?

What is the role of thrombin in the formation of the secondary hemostatic plug?

What is the purpose of counterregulatory measures in the hemostatic process?

What is the role of endothelial cells in hemostasis in a normal cell?

Which of the following is NOT a way in which endothelial cells inhibit thrombus formation in a normal vessel?

Which of the following is NOT a function of endothelial cells in inhibiting coagulation?

Which of the following is NOT a pro-thrombotic activity of endothelial cells in a damaged vessel?

Which of the following is NOT contained in platelet α granules?

Which of the following is NOT a step in plug formation after platelet adhesion?

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