Introduction to Hematology and Hematopoiesis

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Questions and Answers

Where do most plastic cells in the adult body originate from?

  • Bone marrow (correct)
  • Tissues
  • Lymphoid organs
  • Blood

What happens as the hematopoiesis process progresses?

  • Cells lose their multipotent ability and gain specific functions (correct)
  • Cells do not undergo any changes in their potency or function
  • Cells retain their multipotent ability and do not gain specific functions
  • Cells gain multipotent ability and lose specific functions

What are Colony Forming Units (CFUs) responsible for?

  • Recognizing different cell lineages
  • Producing mature blood cells
  • Giving rise to other cells (correct)
  • Forming macrophages in tissues

Where does myelopoiesis occur?

<p>Bone marrow (A)</p> Signup and view all the answers

What is the fate of monocytes during hematopoiesis?

<p>They form macrophages in tissues (A)</p> Signup and view all the answers

Where does lymphopoiesis occur?

<p>Lymphoid organs (C)</p> Signup and view all the answers

Which of the following conditions is characterized by severe reduction/absence of reticulocytes and all erythron in the bone marrow?

<p>Aplastic anemia (B)</p> Signup and view all the answers

Which of the following anemias is characterized by a lack/reduction of precursor and progenitor cells, resulting in absence of erythroblasts in the bone marrow?

<p>Aplastic anemia (A)</p> Signup and view all the answers

Which condition is often associated with BM aplasia and can be caused by thymoma, carcinomas, or hematologic neoplastic diseases?

<p>Acquired erythroblastopenia (aplastic anemia) (A)</p> Signup and view all the answers

Which type of anemia is primarily due to damage in erythroblasts' precursors, resulting in reduced erythroblastogenesis?

<p>Congenital erythroblastopenia (B)</p> Signup and view all the answers

Which condition can cause a transient reduction in one or all bone marrow lineages, including a decrease in erythroblasts?

<p>Viral infections (C)</p> Signup and view all the answers

Which type of anemia is characterized by reduced RBC survival and can be caused by autoimmune hemolysis or erythrocyte structural and metabolic dysfunction?

<p>Autoimmune hemolysis (C)</p> Signup and view all the answers

Which condition is characterized by reduced hemoglobin synthesis, either in the Heme or in the Globin part?

<p>Thalassemias (B)</p> Signup and view all the answers

(Select all that apply) Which conditions are often characterized by BM aplasia?

<p>(Aplastic anemia) (A)</p> Signup and view all the answers

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