Introduction to Enzymes: Properties, Classifications, and Kinetics
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Questions and Answers

What type of inhibition does sulfanilamide exhibit on the enzyme that converts PABA into folic acid?

  • Uncompetitive inhibition
  • Mixed inhibition
  • Noncompetitive inhibition
  • Competitive inhibition (correct)

    • How does competitive inhibition affect the enzyme function compared to noncompetitive inhibition?

  • Impairs the enzyme function without structural resemblance to the substrate
  • Can be overcome by high substrate concentrations (correct)
  • Binds to ES not free E
  • Binds to the active site on the enzyme surface

    • What is a characteristic of noncompetitive inhibitors regarding their binding sites on enzymes?

  • Binds to ES not free E (correct)
  • Impairs the enzyme function without structural resemblance to the substrate
  • Binds to the active site on the enzyme surface
  • Can be overcome by high substrate concentrations

    • Which statement accurately describes uncompetitive inhibition?

    <p>Can be overcome by high substrate concentrations</p> Signup and view all the answers

    How does increasing substrate concentration affect competitive inhibition?

    <p>Overcomes inhibitor binding</p> Signup and view all the answers

    What distinguishes uncompetitive inhibition from competitive inhibition in terms of inhibitor binding sites?

    <p>[I] binds to ES not free E</p> Signup and view all the answers

    In noncompetitive inhibition, what is a key characteristic of the inhibitor's structural resemblance with the substrate?

    <p><strong>Inhibition cannot be overcome by addition of S</strong></p> Signup and view all the answers

    What is a distinguishing feature of competitive inhibitors in terms of their mechanism of action?

    <p>Inhibitors have structural resemblance with the substrate</p> Signup and view all the answers

    How does uncompetitive inhibition differ from noncompetitive inhibition in terms of overcoming the effects of inhibitors?

    <p>Inhibition by uncompetitive inhibitors is irreversible with increased substrate levels</p> Signup and view all the answers

    What action can help overcome noncompetitive inhibition?

    <p>Increasing [S] favors the inhibition by [I]</p> Signup and view all the answers

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