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Introduction to Enzymes: Properties, Classifications, and Kinetics

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Introduction to Enzymes: Properties, Classifications, and Kinetics

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Questions and Answers

What type of inhibition does sulfanilamide exhibit on the enzyme that converts PABA into folic acid?

Uncompetitive inhibition

Mixed inhibition

Noncompetitive inhibition

Competitive inhibition (correct)

How does competitive inhibition affect the enzyme function compared to noncompetitive inhibition?

Impairs the enzyme function without structural resemblance to the substrate

Can be overcome by high substrate concentrations (correct)

Binds to ES not free E

Binds to the active site on the enzyme surface

What is a characteristic of noncompetitive inhibitors regarding their binding sites on enzymes?

Binds to ES not free E (correct)

Impairs the enzyme function without structural resemblance to the substrate

Binds to the active site on the enzyme surface

Can be overcome by high substrate concentrations

Which statement accurately describes uncompetitive inhibition?

Can be overcome by high substrate concentrations (C) Signup and view all the answers

How does increasing substrate concentration affect competitive inhibition?

Overcomes inhibitor binding (A) Signup and view all the answers

What distinguishes uncompetitive inhibition from competitive inhibition in terms of inhibitor binding sites?

[I] binds to ES not free E (D) Signup and view all the answers

In noncompetitive inhibition, what is a key characteristic of the inhibitor's structural resemblance with the substrate?

Inhibition cannot be overcome by addition of S (A) Signup and view all the answers

What is a distinguishing feature of competitive inhibitors in terms of their mechanism of action?

Inhibitors have structural resemblance with the substrate (D) Signup and view all the answers

How does uncompetitive inhibition differ from noncompetitive inhibition in terms of overcoming the effects of inhibitors?

Inhibition by uncompetitive inhibitors is irreversible with increased substrate levels (C) Signup and view all the answers

What action can help overcome noncompetitive inhibition?

Increasing [S] favors the inhibition by [I] (B) Signup and view all the answers