Podcast
Questions and Answers
Which characteristic distinguishes acute leukemia from chronic leukemia?
Which characteristic distinguishes acute leukemia from chronic leukemia?
- Chronic leukemia primarily affects lymphocytes.
- Acute leukemia is more common in adults.
- Chronic leukemia is easier to treat.
- Acute leukemia develops and worsens rapidly. (correct)
In Acute Lymphoblastic Leukemia (ALL), what is the primary issue with the white blood cells (WBCs)?
In Acute Lymphoblastic Leukemia (ALL), what is the primary issue with the white blood cells (WBCs)?
- The WBCs do not mature correctly and do not work properly. (correct)
- The WBCs are not produced in sufficient quantities.
- The WBCs mature too quickly, causing overproduction.
- The WBCs attack healthy cells instead of infections.
What genetic abnormality is specifically associated with Acute Promyelocytic Leukemia (APL)?
What genetic abnormality is specifically associated with Acute Promyelocytic Leukemia (APL)?
- Duplication of chromosome 8
- Deletion of a portion of chromosome 21
- Translocation between chromosomes 9 and 22
- Translocation between chromosomes 15 and 17 (correct)
What is the hallmark of Chronic Myelogenous Leukemia (CML) regarding chromosome structure?
What is the hallmark of Chronic Myelogenous Leukemia (CML) regarding chromosome structure?
Which type of leukemia is characterized by the overproduction of myelomonocytic cells and commonly occurs in children under the age of four?
Which type of leukemia is characterized by the overproduction of myelomonocytic cells and commonly occurs in children under the age of four?
Which statement accurately describes the cause of most cases of childhood leukemia?
Which statement accurately describes the cause of most cases of childhood leukemia?
In the context of leukemia, what does the term 'hematological malignancy' refer to?
In the context of leukemia, what does the term 'hematological malignancy' refer to?
If a child is diagnosed with Acute Lymphoblastic Leukemia (ALL), which type of white blood cell is primarily affected by this disease?
If a child is diagnosed with Acute Lymphoblastic Leukemia (ALL), which type of white blood cell is primarily affected by this disease?
How does the presence of too many immature white blood cells (WBCs) in the bone marrow affect other blood cells?
How does the presence of too many immature white blood cells (WBCs) in the bone marrow affect other blood cells?
What is the typical outcome of the genetic change (chromosome translocation) found in patients with APL?
What is the typical outcome of the genetic change (chromosome translocation) found in patients with APL?
Why can the chromosome translocation in Chronic Myelogenous Leukemia (CML) lead to uncontrolled cell growth?
Why can the chromosome translocation in Chronic Myelogenous Leukemia (CML) lead to uncontrolled cell growth?
In Juvenile Myelomonocytic Leukemia (JMML), where are myelomonocytic cells produced and where do they typically invade?
In Juvenile Myelomonocytic Leukemia (JMML), where are myelomonocytic cells produced and where do they typically invade?
If a leukemia patient has too many immature white blood cells being produced, what is a likely consequence?
If a leukemia patient has too many immature white blood cells being produced, what is a likely consequence?
In the context of Acute Myelogenous Leukemia (AML) in children, what is the role of myeloblasts?
In the context of Acute Myelogenous Leukemia (AML) in children, what is the role of myeloblasts?
How does Chronic Lymphocytic Leukemia (CLL) differ from other types of leukemia mentioned?
How does Chronic Lymphocytic Leukemia (CLL) differ from other types of leukemia mentioned?
Childhood leukemia is most commonly what type?
Childhood leukemia is most commonly what type?
What is the primary site of leukemia development?
What is the primary site of leukemia development?
What percentage of childhood leukemia diagnoses does Acute Lymphoblastic Leukemia (ALL) account for?
What percentage of childhood leukemia diagnoses does Acute Lymphoblastic Leukemia (ALL) account for?
What distinguishes Chronic Myelogenous Leukemia (CML) from other forms of leukemia?
What distinguishes Chronic Myelogenous Leukemia (CML) from other forms of leukemia?
Among the types of leukemia you have learned about, which is the least common in children?
Among the types of leukemia you have learned about, which is the least common in children?
Flashcards
What is Leukemia?
What is Leukemia?
Cancer of the blood that originates in the bone marrow.
Acute Leukemia
Acute Leukemia
Develops and worsens quickly, over days to weeks.
Chronic Leukemia
Chronic Leukemia
Develops slowly over months/years; more common in adults.
Acute Lymphoblastic Leukemia (ALL)
Acute Lymphoblastic Leukemia (ALL)
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Acute Myelogenous Leukemia (AML)
Acute Myelogenous Leukemia (AML)
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Acute Promyelocytic Leukemia (APL)
Acute Promyelocytic Leukemia (APL)
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Chronic Myelogenous Leukemia (CML)
Chronic Myelogenous Leukemia (CML)
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Chronic Lymphocytic Leukemia (CLL)
Chronic Lymphocytic Leukemia (CLL)
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Juvenile Myelomonocytic Leukemia (JMML)
Juvenile Myelomonocytic Leukemia (JMML)
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Study Notes
Course Details
- The lecturer is Prof. Andrew Zisserman
- Teaching Assistants include Dr. Iro Laina, Dr. Johannes Linder, Oisin Mac Aodha, and Simon Hadfield
- Lectures are on Tuesdays from 14:00-16:00 in the Rex Thompson Room
- Practicals are on Fridays from 14:00-16:00 in the Thom Building
- The course website is available on the department website
- Recommended books are "Computer Vision: Algorithms and Applications" by Richard Szeliski, and "Computer Vision: Models, Learning, and Inference" by Simon Prince
- Online discussions will be held on Piazza
Course Overview
- An introduction to computer vision will be provided
- Image formation principles described
- Feature detection and matching algorithms explained
- Image segmentation techniques discussed
- Object recognition methods covered
- 3D vision explored
- Motion analysis techniques investigated
Assessment
- Practicals are worth 50% of the final grade
- Practical assessments are based on correctness, efficiency, and code clarity
- Late practical submissions are penalized
- The exam is worth 50% of the final grade
- The exam is closed book
- Exams test understanding of concepts and algorithms
- Past exam papers are not available
What is Computer Vision?
- Computer vision involves enabling computers to "see"
- It includes extracting meaningful information from images
- Computer vision aims to mimic human vision capabilities
- Applications include image search, robotics, medical imaging, security, and autonomous driving
Image Formation
- How images are formed is studied
- Camera models are used
- Geometric transformations are implemented
- Radiometry concepts are introduced
- Color science is used
Pinhole Camera Model
- This camera model is a simple representation
- It has no lenses and images are inverted
- It uses perspective projection to map 3D world points to 2D image points
- The pinhole camera model equation: $x = f \frac{X}{Z}$, $y = f \frac{Y}{Z}$, where $(X, Y, Z)$ is a 3D point, $(x, y)$ is the 2D projection, and $f$ is the focal length
- The Matrix form (including camera center C) $\begin{bmatrix} x \ y \ 1 \end{bmatrix} = \begin{bmatrix} f & 0 & 0 \ 0 & f & 0 \ 0 & 0 & 1 \end{bmatrix} \begin{bmatrix} R & -RC \end{bmatrix} \begin{bmatrix} X \ Y \ Z \ 1 \end{bmatrix}$, where $R$ is the rotation matrix and $C$ is the camera center
Radial Lens Distortion
- Lenses introduce distortion in images
- Radial distortion, including barrel and pincushion distortion, is common
- Correction for distortion: $x_{corrected} = x(1 + k_1r^2 + k_2r^4 +...)$, $y_{corrected} = y(1 + k_1r^2 + k_2r^4 +...)$, where $(x, y)$ is the original point, $(x_{corrected}, y_{corrected})$ is the corrected point, $k_1, k_2$ are distortion coefficients, and $r = \sqrt{x^2 + y^2}$
Homogeneous Coordinates
- Points are represented in projective space
- An extra coordinate is added for representation
- A 2D point $(x, y)$ becomes $(x, y, 1)$
- A 3D point $(x, y, z)$ becomes $(x, y, z, 1)$
- Transformations can be represented as matrices using this system
- Scaling equivalence: $(x, y, z) = k(x, y, z)$
- A point at infinity: $(x, y, 0)$
- Original line equation: $ax + by + c = 0$ becomes $\begin{bmatrix} a & b & c \end{bmatrix} \begin{bmatrix} x \ y \ 1 \end{bmatrix} = 0$
Coordinate Transformations
- Translation transformation: $\begin{bmatrix} x' \ y' \ 1 \end{bmatrix} = \begin{bmatrix} 1 & 0 & t_x \ 0 & 1 & t_y \ 0 & 0 & 1 \end{bmatrix} \begin{bmatrix} x \ y \ 1 \end{bmatrix}$
- Rotation transformation: $\begin{bmatrix} x' \ y' \end{bmatrix} = \begin{bmatrix} cos\theta & -sin\theta \ sin\theta & cos\theta \end{bmatrix} \begin{bmatrix} x \ y \end{bmatrix}$
- Scaling transformation: $\begin{bmatrix} x' \ y' \end{bmatrix} = \begin{bmatrix} s_x & 0 \ 0 & s_y \end{bmatrix} \begin{bmatrix} x \ y \end{bmatrix}$
- Affine transformation: $\begin{bmatrix} x' \ y' \ 1 \end{bmatrix} = \begin{bmatrix} a & b & c \ d & e & f \ 0 & 0 & 1 \end{bmatrix} \begin{bmatrix} x \ y \ 1 \end{bmatrix}$
- Projective transformation (Homography): $\begin{bmatrix} x' \ y' \ w \end{bmatrix} = \begin{bmatrix} a & b & c \ d & e & f \ g & h & i \end{bmatrix} \begin{bmatrix} x \ y \ 1 \end{bmatrix}$, where $x = x'/w$ and $y = y'/w$
Radiometry
- Radiometry is the measurement of light
- Irradiance: power measured per unit area
- Radiance: power measured per unit area per unit solid angle
- BRDF (Bidirectional Reflectance Distribution Function) is important
- A Lambertian surface reflects light uniformly in all directions
- A Specular surface reflects light in a mirror-like direction
Color
- Color perception is a key concept
- Color spaces include RGB, HSV, and Lab
- Color constancy is an important feature
- White balance is considered
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