10 Questions
What type of proteins play a critical role in immune defenses and primarily signal through receptors linked to JAK kinases?
Cytokines
Which subunit of G proteins can bind both GDP and GTP?
Alpha subunit
What happens to the alpha subunit of a G protein when it binds to GTP?
It dissociates from the beta and gamma subunits
What is the function of beta and gamma subunits in G proteins?
Anchor the alpha subunit in the membrane
Which proteins are termed plasma membrane effector proteins for their role in mediating cell responses?
Enzymes
What happens to the activated alpha subunit of a G protein after dissociating from beta and gamma subunits?
It links up with an ion channel or enzyme
Which proteins are associated with receptors in signaling pathways involving multiple distinct members like G proteins?
G-Protein-Coupled Receptors
What happens to the affinity of the alpha subunit of a G protein when the receptor is activated?
It increases for GTP
What is the name given to the family of heterotrimeric proteins located on the cytosolic surface of the plasma membrane associated with G-Protein-Coupled Receptors?
G Proteins
What proteins play a critical role in immune defenses and signal via receptors linked to JAK kinases?
Cytokines
Learn about cell signaling mechanisms in physiology, focusing on receptors and different cell-to-cell signaling pathways. Explore how various chemical messengers interact with membrane receptors and the role of lipidsoluble messengers in intracellular signaling.
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