Podcast
Questions and Answers
What distinguishes facilitated diffusion from simple diffusion?
What distinguishes facilitated diffusion from simple diffusion?
- Facilitated diffusion is slower than simple diffusion.
- Facilitated diffusion requires energy input.
- Facilitated diffusion occurs against the concentration gradient.
- Facilitated diffusion uses transport proteins. (correct)
Why are polar or charged substances unable to easily diffuse across cell membranes?
Why are polar or charged substances unable to easily diffuse across cell membranes?
- They cannot interact with transport proteins.
- Cell membranes are exclusively permeable to hydrophobic substances. (correct)
- They require ATP for movement.
- Their charge disrupts the membrane lipid bilayer.
What role does ATP play in active transport?
What role does ATP play in active transport?
- ATP increases the membrane permeability.
- ATP supplies energy to move solutes against their concentration gradients. (correct)
- ATP is used to create transport proteins.
- ATP helps maintain the cell's resting potential.
How does aquaporin enhance the transport of water in cells?
How does aquaporin enhance the transport of water in cells?
What characteristic of calcium ion transport illustrates active transport?
What characteristic of calcium ion transport illustrates active transport?
What was significant about Dr. Peter Agre's research on aquaporins?
What was significant about Dr. Peter Agre's research on aquaporins?
What defines the concept of selective permeability in cell membranes?
What defines the concept of selective permeability in cell membranes?
Why would a researcher use frog eggs to test the function of a transport protein?
Why would a researcher use frog eggs to test the function of a transport protein?
What is the primary role of cofactors in enzymatic reactions?
What is the primary role of cofactors in enzymatic reactions?
How do competitive inhibitors affect enzyme activity?
How do competitive inhibitors affect enzyme activity?
Which statement accurately describes noncompetitive inhibitors?
Which statement accurately describes noncompetitive inhibitors?
What is the role of feedback inhibition in metabolic regulation?
What is the role of feedback inhibition in metabolic regulation?
What distinguishes coenzymes from cofactors?
What distinguishes coenzymes from cofactors?
Which of the following statements about enzyme inhibitors is true?
Which of the following statements about enzyme inhibitors is true?
Why are vitamins important in the context of coenzymes?
Why are vitamins important in the context of coenzymes?
In which way can an allosteric site influence enzyme function?
In which way can an allosteric site influence enzyme function?
What is the primary difference between kinetic energy and potential energy?
What is the primary difference between kinetic energy and potential energy?
Which statement accurately describes the first law of thermodynamics?
Which statement accurately describes the first law of thermodynamics?
In what way do exergonic reactions differ from endergonic reactions?
In what way do exergonic reactions differ from endergonic reactions?
Which process describes the breakdown of compounds to release energy?
Which process describes the breakdown of compounds to release energy?
What is the significance of ATP in cellular work?
What is the significance of ATP in cellular work?
How do catabolic and anabolic processes relate to body weight?
How do catabolic and anabolic processes relate to body weight?
Which of the following statements about entropy is true?
Which of the following statements about entropy is true?
What role does phosphorylation play in cellular processes?
What role does phosphorylation play in cellular processes?
What characterizes passive transport across a cell membrane?
What characterizes passive transport across a cell membrane?
Which statement accurately describes osmosis?
Which statement accurately describes osmosis?
What happens to animal cells placed in a hypertonic solution?
What happens to animal cells placed in a hypertonic solution?
In what condition do plant cells become flaccid?
In what condition do plant cells become flaccid?
What is the effect of placing cells in a 0.5% sucrose solution when separated from a 2% sucrose solution?
What is the effect of placing cells in a 0.5% sucrose solution when separated from a 2% sucrose solution?
What is tonicity in relation to cell membranes?
What is tonicity in relation to cell membranes?
Which of the following distinguishes a hypotonic solution?
Which of the following distinguishes a hypotonic solution?
What role do contractile vacuoles serve in freshwater Paramecium?
What role do contractile vacuoles serve in freshwater Paramecium?
How does ATP transfer energy during cellular processes?
How does ATP transfer energy during cellular processes?
What role do enzymes play in cellular reactions?
What role do enzymes play in cellular reactions?
What is the significance of the ATP cycle in cells?
What is the significance of the ATP cycle in cells?
Which statement accurately describes the role of active sites in enzymes?
Which statement accurately describes the role of active sites in enzymes?
What happens during the hydrolysis of ATP?
What happens during the hydrolysis of ATP?
Why do enzymes not get consumed in the reactions they catalyze?
Why do enzymes not get consumed in the reactions they catalyze?
How is energy coupling achieved using ATP?
How is energy coupling achieved using ATP?
What defines the specificity of an enzyme for its substrate?
What defines the specificity of an enzyme for its substrate?
How would you classify a solution with a higher solute concentration outside a cell than inside, affecting cell volume?
How would you classify a solution with a higher solute concentration outside a cell than inside, affecting cell volume?
What role do transport proteins play in cellular processes?
What role do transport proteins play in cellular processes?
Which process involves the engulfing of solid particles by a cell?
Which process involves the engulfing of solid particles by a cell?
What is the difference between kinetic energy and potential energy?
What is the difference between kinetic energy and potential energy?
Which of the following correctly states one of the laws of thermodynamics?
Which of the following correctly states one of the laws of thermodynamics?
In which type of reaction do products contain more energy than reactants?
In which type of reaction do products contain more energy than reactants?
What is the primary function of ATP in cells?
What is the primary function of ATP in cells?
Flashcards
Diffusion
Diffusion
The movement of particles from an area of high concentration to an area of low concentration.
Passive Transport
Passive Transport
A type of passive transport where substances move across a membrane without requiring cellular energy.
Osmosis
Osmosis
The diffusion of water across a selectively permeable membrane from a region of high water concentration to a region of low water concentration.
Hypertonic Solution
Hypertonic Solution
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Hypotonic Solution
Hypotonic Solution
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Isotonic Solution
Isotonic Solution
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Tonicity
Tonicity
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Contractile Vacuoles
Contractile Vacuoles
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Energy
Energy
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Kinetic energy
Kinetic energy
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Potential energy
Potential energy
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Chemical energy
Chemical energy
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Thermodynamics
Thermodynamics
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1st Law of Thermodynamics
1st Law of Thermodynamics
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2nd Law of Thermodynamics
2nd Law of Thermodynamics
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Exergonic reaction
Exergonic reaction
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Facilitated Diffusion
Facilitated Diffusion
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Aquaporin
Aquaporin
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Selective Permeability
Selective Permeability
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ATP (Adenosine Triphosphate)
ATP (Adenosine Triphosphate)
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Active Transport (mechanism)
Active Transport (mechanism)
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Concentration Gradient
Concentration Gradient
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What are cofactors?
What are cofactors?
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What are coenzymes?
What are coenzymes?
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What is a competitive inhibitor?
What is a competitive inhibitor?
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What is a noncompetitive inhibitor?
What is a noncompetitive inhibitor?
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What is feedback inhibition?
What is feedback inhibition?
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How do enzyme inhibitors affect biological processes?
How do enzyme inhibitors affect biological processes?
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What is the mechanism of competitive inhibitors?
What is the mechanism of competitive inhibitors?
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What is the mechanism of noncompetitive inhibitors?
What is the mechanism of noncompetitive inhibitors?
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Transport proteins
Transport proteins
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Exocytosis
Exocytosis
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Endocytosis
Endocytosis
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Phagocytosis
Phagocytosis
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Receptor-mediated endocytosis
Receptor-mediated endocytosis
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How does ATP transfer energy?
How does ATP transfer energy?
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What are exergonic and endergonic reactions?
What are exergonic and endergonic reactions?
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What is the ATP cycle?
What is the ATP cycle?
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What is activation energy?
What is activation energy?
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What is the active site of an enzyme?
What is the active site of an enzyme?
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Describe the catalytic cycle of an enzyme.
Describe the catalytic cycle of an enzyme.
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Explain the graph showing a reaction with and without an enzyme
Explain the graph showing a reaction with and without an enzyme
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Study Notes
Introduction to Cell Biology
- The plasma membrane and its proteins enable cells to survive and function.
- Key processes covered in the chapter include membranes, energy, and enzymes.
Membrane Structure and Function
- Biologists use the fluid mosaic model to describe membrane structure. It involves diverse protein molecules suspended in a fluid phospholipid bilayer.
- Plasma membranes exhibit selective permeability.
- Membrane proteins perform various functions.
Membrane Proteins
- Junction Proteins: Form intercellular junctions that connect adjacent cells.
- Enzyme Proteins: Fix to membranes, localizing metabolic pathways.
- Transport Proteins: Facilitate diffusion and active transport.
- Receptor Proteins: Bind to signaling molecules, activating other molecules within the cell.
- Attachment Proteins: Attach to the extracellular matrix and cytoskeleton, coordinating internal and external changes.
- Glycoproteins: Serve as ID tags, recognized by membrane proteins of other cells.
Transport
- Diffusion: The tendency of particles to spread evenly in an available space.
- Simple Diffusion: Movement of small nonpolar molecules across a membrane.
- Facilitated Diffusion: Polar or charged substances require specific transport proteins to move down their concentration gradient, which doesn't use energy
- Osmosis: The diffusion of water across a selectively permeable membrane.
- Active Transport: Cells require energy input to move molecules against their concentration gradient.
- Primary Active Transport: Direct use of ATP hydrolysis
- Secondary Active Transport: Coupled with another solute.
- Aquaporins: Special protein channels allowing rapid water diffusion across cell membranes
- Kidney Dialysis: Net diffusion of toxins from blood to dialysis fluid.
- Isotonic: Solutions with the equal solute concentration compared to inside the cell, normal for animal cells, flaccid for plant cells.
- Hypertonic: Solutions with higher solute concentration than inside the cell; cells shrink.
- Hypotonic: Solutions with lower solute concentration than inside the cell; cells swell.
Exocytosis and Endocytosis
- Exocytosis: Exports bulky molecules (proteins or polysaccharides).
- Types of Endocytosis:
- Phagocytosis: Engulfment of particles (forming a vacuole).
- Pinocytosis: Engulfment of liquids (forming a vacuole).
- Receptor-mediated endocytosis: Specific molecules bound to receptors in coated pits for entry into the cell.
- Material is packaged inside vesicles for transport and fusing with the membrane for release.
Energy and Cells
- Energy: The capacity to cause change or do work.
- Kinetic Energy: Energy of motion.
- Potential Energy: Stored energy, including chemical energy.
- Thermodynamics:
- First Law: Energy can change form but cannot be created or destroyed.
- Second Law: Energy transformations increase entropy and some energy is lost as heat.
- Exergonic Reaction: Releases energy.
- Endergonic Reaction: Requires energy.
- Metabolism: All chemical reactions in a cell.
- Catabolism: Breakdown of molecules.
- Anabolism: Building of molecules.
ATP
- ATP: Powers nearly all forms of cellular work.
- Phosphorylation: Transfer of a phosphate group from ATP to another molecule.
- ATP cycle involves continuous phosphorylation and hydrolysis.
Enzymes
- Enzymes: Catalysts, decreasing activation energy for reactions without being consumed.
- Active site: Specific region where the substrate fits, creating an induced fit.
- Cofactors: Nonprotein helpers binding to the active site and functioning in catalysis.
- Coenzymes: Organic cofactors often vitamins.
- Enzyme inhibitors: Substances that decrease enzyme activity.
- Competitive Inhibitors: Block the active site.
- Non-competitive Inhibitors: Bind to a different site, changing the enzyme's shape
- Feedback Inhibition: The end product of a metabolic pathway inhibits an enzyme early in the pathway.
Research on Membrane Proteins
- Dr. Peter Agre received the 2003 Nobel Prize in Chemistry for his discovery of aquaporins.
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