Introduction to Carbohydrates

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Questions and Answers

Deoxyribose, a carbohydrate, deviates from the general carbohydrate formula $C_n(H_2O)_n$ because it:

  • Contains nitrogen, phosphorus, or sulfur.
  • Functions as a physiological anticoagulant.
  • Does not have hydrogen and oxygen in a 2:1 ratio. (correct)
  • Is a structural component of brain cells.

Which of the following statements accurately describes the role of carbohydrates in the human body?

  • They are the primary structural component, constituting the majority of body mass.
  • They are involved in the synthesis of antibodies and hormones.
  • They are a major source of energy and serve as stored energy. (correct)
  • They primarily serve as a source of genetic information.

How do carbohydrates contribute to protein sparing in the body?

  • By directly synthesizing essential amino acids.
  • By being a component of nucleic acids.
  • By decreasing the need for proteins to be used for energy. (correct)
  • By reducing the breakdown of fatty acids and preventing ketosis.

In what way do carbohydrates participate in biological recognition processes?

<p>As components of immunoglobulins. (C)</p> Signup and view all the answers

What is the primary function of heparan, a carbohydrate derivative, in the body?

<p>To act as a physiological anticoagulant. (C)</p> Signup and view all the answers

In the context of intravenous feeding, what role do carbohydrates play?

<p>They are a source of sterile IV solutions. (A)</p> Signup and view all the answers

How are carbohydrates utilized in the preparation of sugar-coated tablets?

<p>As diluents and binders. (A)</p> Signup and view all the answers

Which property of certain carbohydrates makes them useful as laxatives?

<p>Their mucilage content. (B)</p> Signup and view all the answers

In what pharmaceutical application is agar, a carbohydrate, primarily used?

<p>As a nutrient medium for bacteria and tissue cultures. (D)</p> Signup and view all the answers

How do carbohydrates function as disintegrants in tablets?

<p>By facilitating the breakdown of the tablet into smaller particles. (C)</p> Signup and view all the answers

Flashcards

Carbohydrates

Chemically defined as polyhydroxy aldehydes and ketones.

Importance of Carbohydrates

Major source of energy (4.1 Cal/g); stored as glycogen; roles in protein sparing action.

Medicinal Functions of Carbohydrates

Flavoring agents, dietary fiber, biological recognition, brain cell components, and nucleic acid components.

Other medicinal functions of carbohydrates

Physiological anticoagulant, plasma expanders, parenteral nutrition, and binders in tablets.

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Medicinal Function of Carbohydrates cont.

They act as disintegrators in tablets and diagnostic markers.

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Importance of Carbohydrates in Pharmacy

Preparation of simple syrup, diluents/binders, infant food, IV solutions, anti-diarrhea drugs, laxatives/diuretics, emulsifiers, nutrient media, surgical dressings.

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Study Notes

  • Carbohydrates are chemically defined as polyhydroxy aldehydes and ketones.
  • The name carbohydrate, signifying hydrates of carbon, comes from the first studied compounds, like glucose, with the empirical formula C1H2O1, showing a 2:1 hydrogen-oxygen ratio.
  • Carbohydrates contain hydrogen and oxygen, but not always in the same proportion as water, such as deoxyribose with the molecular formula C5H10O4.
  • General formula for hydrates of carbon is Cn(H2O)n
  • Carbohydrates are the most abundant bio-molecules on earth, but only constitute 1% of human body mass.

Importance of Carbohydrates

  • Carbohydrates are a major source of energy providing 4.1 Cal/g.
  • They serve as stored energy in the form of glycogen in the liver and muscles.
  • Some carbohydrates contain nitrogen (N), phosphorus (P), or sulfur (S) and play a role in protein sparing action.
  • Carbohydrates reduce the breakdown of fatty acids and prevent ketosis, a condition with raised ketone body levels associated with abnormal fat metabolism and diabetes mellitus.

Medicinal Functions of Carbohydrates

  • Carbohydrates act as flavoring and sweetening agents.
  • They are a part of dietary fiber, like cellulose.
  • Carbohydrates are involved in biological recognition processes of immunoglobulin, a class of proteins in the serum and immune cells.
  • They are important components of brain cells, such as neuraminic acids, cerebrosides (Glycolipids), and gangliosides.
  • They are important components of nucleic acids as pentose sugars, including ribose and deoxyribose.
  • Heparan is a physiological anticoagulant playing a medicinal role.
  • Used as plasma expanders, agents that increase plasma volume via osmotic pressure to treat hemorrhage or shock (e.g., Dextrin).
  • Carbohydrates given via parenteral nutrition, supplies nutrients intravenously.
  • Starches function as binders in tablets.
  • Carbohydrates act as disintegrators in tablets.
  • Act as diagnostic markers aiding disease diagnosis through genetic variants and protein levels in body fluids.

Carbohydrates in Pharmacy

  • Used in preparation of simple syrups using sucrose.
  • Act as diluents and binders in tablets (using lactose, starch, gums) and for coating sugar-coated tablets (using liquid glucose).
  • Help in infant food preparation, like starch and dextrin.
  • Used in sterile IV solutions, using dextrose.
  • Help in anti-diarrhea drugs (pectin)
  • Carbohydrates act as laxatives (mucilage, lactulose), antacids (surfactants), or diuretic drugs (mannitol and sorbitol).
  • Carbohydrates act as emulsifying agents (gums).
  • They act as nutrient media for bacteria and tissue cultures, using agar.
  • Used in surgical dressings (cellulose) and plasters (gums).

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