Podcast
Questions and Answers
A patient presents with intense itching, darker urine, and pale stools during her third trimester. Which of the following conditions is MOST likely?
A patient presents with intense itching, darker urine, and pale stools during her third trimester. Which of the following conditions is MOST likely?
- Eclampsia
- Preeclampsia (correct)
- Intrahepatic cholestasis of pregnancy
- Gestational diabetes
Intrahepatic cholestasis of pregnancy (ICP) is associated with an increased risk of which fetal complication?
Intrahepatic cholestasis of pregnancy (ICP) is associated with an increased risk of which fetal complication?
- Fetal growth restriction
- Spina bifida (correct)
- Intrauterine fetal death (IUFD)
- Macrosomia
A pregnant patient is diagnosed with intrahepatic cholestasis of pregnancy. The obstetrician orders twice-weekly NSTs. What is the MOST likely rationale for this?
A pregnant patient is diagnosed with intrahepatic cholestasis of pregnancy. The obstetrician orders twice-weekly NSTs. What is the MOST likely rationale for this?
- To monitor for signs of maternal hypertension
- To evaluate the effectiveness of ursodeoxycholic acid treatment (correct)
- To assess fetal well-being and detect early signs of distress
- To screen for gestational diabetes
Which laboratory finding is MOST consistent with a diagnosis of intrahepatic cholestasis of pregnancy?
Which laboratory finding is MOST consistent with a diagnosis of intrahepatic cholestasis of pregnancy?
A characteristic symptom of intrahepatic cholestasis of pregnancy, which often prompts patients to seek medical attention, is:
A characteristic symptom of intrahepatic cholestasis of pregnancy, which often prompts patients to seek medical attention, is:
A patient with intrahepatic cholestasis of pregnancy (ICP) is at an increased risk for postpartum hemorrhage. Which mechanism contributes MOST significantly to this risk?
A patient with intrahepatic cholestasis of pregnancy (ICP) is at an increased risk for postpartum hemorrhage. Which mechanism contributes MOST significantly to this risk?
Why is intrahepatic cholestasis of pregnancy often referred to as a 'diagnosis of exclusion'?
Why is intrahepatic cholestasis of pregnancy often referred to as a 'diagnosis of exclusion'?
What is a key characteristic of the itching associated with intrahepatic cholestasis of pregnancy?
What is a key characteristic of the itching associated with intrahepatic cholestasis of pregnancy?
Which statement best describes the understanding of the etiology of intrahepatic cholestasis of pregnancy (ICP)?
Which statement best describes the understanding of the etiology of intrahepatic cholestasis of pregnancy (ICP)?
What aspect of intrahepatic cholestasis of pregnancy highlights the importance of considering earlier delivery?
What aspect of intrahepatic cholestasis of pregnancy highlights the importance of considering earlier delivery?
Flashcards
Intrahepatic Cholestasis of Pregnancy (ICP)
Intrahepatic Cholestasis of Pregnancy (ICP)
Liver disorder in pregnancy leading to bile build-up.
ICP Symptom
ICP Symptom
Generalized itching, often with pruritus, and a similar itching area to scabies.
Lab Findings in ICP
Lab Findings in ICP
Elevated total serum bile acid levels and transaminases, potentially causing darker urine and pale stools.
Risks Associated with ICP
Risks Associated with ICP
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Management of ICP
Management of ICP
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Hemorrhage Risk in ICP
Hemorrhage Risk in ICP
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ICP: Diagnosis of Exclusion
ICP: Diagnosis of Exclusion
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Study Notes
- Intrahepatic Cholestasis of Pregnancy is a hormonally influenced cholestasis
Symptoms
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Generalized itching, often with pruritus
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Exhibits similar itching pattern to scabies
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Intense itching on palms of hands, soles of feet or all over the body
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Absence of a clear etiology
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Diagnosis of exclusion
Risks
- Increased risk of preterm delivery
- Possibility of meconium passage
- Potential intrapartum fetal heart rate (FHR) abnormalities
- Risk of fetal death as intrauterine fetal death (IUFD)
Additional Symptoms & Risks
- Elevated total serum bile acid levels and transaminases
- May result in darker urine and pale stools
- May require twice weekly non-stress tests (NSTs)
- Could lead to earlier delivery
- Increased hemorrhage risk
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Description
Intrahepatic Cholestasis of Pregnancy is a hormonally influenced cholestasis, diagnosed by exclusion. Symptoms include generalized itching, elevated bile acid levels, and transaminases. Risks involve preterm delivery, meconium passage, FHR abnormalities, and potential fetal death.
