Podcast
Questions and Answers
What is the composition of a G protein?
What is the composition of a G protein?
- α, β, δ
- α, β, γ (correct)
- β, γ, δ
- α, γ, δ
In the unstimulated state, the α subunit of a G protein is bound to:
In the unstimulated state, the α subunit of a G protein is bound to:
- ATP
- ADP
- GTP
- GDP (correct)
What happens to the GTP-bound α subunit of a G protein when activated by a ligand-bound receptor?
What happens to the GTP-bound α subunit of a G protein when activated by a ligand-bound receptor?
- It dissociates from the βγ dimer (correct)
- It activates phospholipase C
- It binds back to the βγ dimer
- It associates with the receptor
Which enzyme is activated by cAMP produced in response to GPCR activation?
Which enzyme is activated by cAMP produced in response to GPCR activation?
What is the cellular response to activation of the β2 Adrenergic Receptor?
What is the cellular response to activation of the β2 Adrenergic Receptor?
What characterizes Enzyme-Linked Receptors?
What characterizes Enzyme-Linked Receptors?
Which of the following receptors are directly coupled to ion channels, allowing for rapid electrical signal transduction?
Which of the following receptors are directly coupled to ion channels, allowing for rapid electrical signal transduction?
Which type of receptor initiates signaling cascades involving second messengers like cAMP, cGMP, and PIP3?
Which type of receptor initiates signaling cascades involving second messengers like cAMP, cGMP, and PIP3?
Which of the following ligands typically binds to G protein-coupled receptors?
Which of the following ligands typically binds to G protein-coupled receptors?
Which type of receptor is directly involved in the regulation of gene expression?
Which type of receptor is directly involved in the regulation of gene expression?
Which of the following signaling molecules can directly cross the plasma membrane due to their hydrophobic nature?
Which of the following signaling molecules can directly cross the plasma membrane due to their hydrophobic nature?
Which type of receptor is typically associated with tyrosine kinase activity and involved in the regulation of cell growth and differentiation?
Which type of receptor is typically associated with tyrosine kinase activity and involved in the regulation of cell growth and differentiation?
Which of the following statements about G-protein-coupled receptors (GPCRs) is correct?
Which of the following statements about G-protein-coupled receptors (GPCRs) is correct?
What is the primary role of the trimeric G protein in the GPCR signaling pathway?
What is the primary role of the trimeric G protein in the GPCR signaling pathway?
Which of the following is NOT an example of a ligand that can activate GPCRs?
Which of the following is NOT an example of a ligand that can activate GPCRs?
In the context of ion-channel-coupled receptors, what is the primary function of acetylcholine (Ach) at the neuromuscular junction?
In the context of ion-channel-coupled receptors, what is the primary function of acetylcholine (Ach) at the neuromuscular junction?
What is the role of Ca$^{2+}$ ions in the process of muscle contraction triggered by ion-channel-coupled receptors?
What is the role of Ca$^{2+}$ ions in the process of muscle contraction triggered by ion-channel-coupled receptors?
Which of the following statements about the signaling mechanisms of GPCRs and ion-channel-coupled receptors is correct?
Which of the following statements about the signaling mechanisms of GPCRs and ion-channel-coupled receptors is correct?
