15 Questions
What is the primary function of intracellular calcium?
Promoting proliferation
Which process does calcium ion (Ca2+) NOT regulate?
Oxygenation
How do cells regulate their intracellular calcium concentration ([Ca2+]i)?
By using ATPase to expel Ca2+ across the plasma membrane
What is one of the advantages of the large inward gradient of calcium?
Rapid changes in [Ca2+]i
Which mechanism is responsible for setting up and maintaining the gradient of intracellular calcium concentration?
Na+-Ca2+ exchanger across the plasma membrane
Which mechanism allows cells to expel Ca2+ across the plasma membrane?
Ca2+ ATPase
What is one of the disadvantages of the large inward gradient of calcium?
Loss of regulation and cell death
Which organelle serves as a non-rapidly releasable intracellular Ca2+ store?
Mitochondria
What is the primary function of intracellular Ca2+ buffers?
To temporarily bind excess Ca2+ ions
What is responsible for setting up and maintaining the gradient of intracellular calcium concentration?
Relatively impermeable plasma membrane
Which process is NOT directly regulated by calcium ion (Ca2+)?
Metabolism
What is one of the disadvantages of the large inward gradient of calcium?
Ca2+ overload leads to loss of regulation and cell death
Which mechanism allows cells to expel Ca2+ across the plasma membrane?
Na+/Ca2+ exchanger
What is responsible for setting up and maintaining the gradient of intracellular calcium concentration?
Intracellular Ca2+ stores (rapidly releasable and non-rapidly releasable)
What is the primary function of intracellular Ca2+ buffers?
To bind and release Ca2+ based on concentration changes
This lecture focuses on the functions of intracellular calcium, how cells regulate intracellular calcium concentration, and the diverse processes regulated by calcium within cells. The lecturer, Darya S. Abdulateef MBChB, PhD in Physiology, discusses the essential role of calcium in normal cellular function and its involvement in processes like fertilization, proliferation, and secretion.
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