Intracellular Calcium Control Lecture
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Questions and Answers

What is the primary function of intracellular calcium?

  • Regulating neurotransmission
  • Promoting proliferation (correct)
  • Maintaining metabolism
  • Controlling apoptosis
  • Which process does calcium ion (Ca2+) NOT regulate?

  • Fertilization
  • Necrosis
  • Metabolism
  • Oxygenation (correct)
  • How do cells regulate their intracellular calcium concentration ([Ca2+]i)?

  • By using ATPase to expel Ca2+ across the plasma membrane (correct)
  • By increasing plasma membrane permeability
  • By decreasing the number of intracellular Ca2+ stores
  • By decreasing the concentration of Ca2+ buffers
  • What is one of the advantages of the large inward gradient of calcium?

    <p>Rapid changes in [Ca2+]i</p> Signup and view all the answers

    Which mechanism is responsible for setting up and maintaining the gradient of intracellular calcium concentration?

    <p>Na+-Ca2+ exchanger across the plasma membrane</p> Signup and view all the answers

    Which mechanism allows cells to expel Ca2+ across the plasma membrane?

    <p>Ca2+ ATPase</p> Signup and view all the answers

    What is one of the disadvantages of the large inward gradient of calcium?

    <p>Loss of regulation and cell death</p> Signup and view all the answers

    Which organelle serves as a non-rapidly releasable intracellular Ca2+ store?

    <p>Mitochondria</p> Signup and view all the answers

    What is the primary function of intracellular Ca2+ buffers?

    <p>To temporarily bind excess Ca2+ ions</p> Signup and view all the answers

    What is responsible for setting up and maintaining the gradient of intracellular calcium concentration?

    <p>Relatively impermeable plasma membrane</p> Signup and view all the answers

    Which process is NOT directly regulated by calcium ion (Ca2+)?

    <p>Metabolism</p> Signup and view all the answers

    What is one of the disadvantages of the large inward gradient of calcium?

    <p>Ca2+ overload leads to loss of regulation and cell death</p> Signup and view all the answers

    Which mechanism allows cells to expel Ca2+ across the plasma membrane?

    <p>Na+/Ca2+ exchanger</p> Signup and view all the answers

    What is responsible for setting up and maintaining the gradient of intracellular calcium concentration?

    <p>Intracellular Ca2+ stores (rapidly releasable and non-rapidly releasable)</p> Signup and view all the answers

    What is the primary function of intracellular Ca2+ buffers?

    <p>To bind and release Ca2+ based on concentration changes</p> Signup and view all the answers

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