Intraabdominal Infections and Peritonitis Treatment
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Questions and Answers

What is the primary goal of treatment for intra-abdominal infections?

  • To provide supportive care
  • Ameliorate clinical signs and symptoms
  • To achieve a resolution of infection without major organ system complications
  • Correction of the intra-abdominal disease processes or injuries that have caused infection (correct)

What type of peritonitis occurs in critically ill patients and persists or recurs at least 48 hours after adequate management?

  • Tertiary peritonitis (correct)
  • Primary peritonitis
  • Secondary peritonitis
  • Spontaneous bacterial peritonitis

Which of the following pathogens is commonly associated with nosocomial and chronic surgical infections in cirrhotic patients?

  • Aerobes
  • Polymicrobial pathogens
  • Enterococcus species (correct)
  • Anaerobes

What is the characteristic of intra-abdominal infections in terms of the type of pathogens involved?

<p>Polymicrobial with both aerobic and anaerobic pathogens (A)</p> Signup and view all the answers

Which of the following is a secondary goal of treatment for intra-abdominal infections?

<p>Achieve a resolution of infection without major organ system complications (A)</p> Signup and view all the answers

What is primary peritonitis?

<p>An infection of the peritoneal cavity without an evident source in the abdomen (A)</p> Signup and view all the answers

What is the minimum required dwell time for exchange with intraperitoneal antibiotics?

<p>6 hours (B)</p> Signup and view all the answers

Which pathogen is commonly associated with cholecystitis?

<p>Escherichia coli (C)</p> Signup and view all the answers

What is the success rate of ERCP in the treatment of cholangitis?

<p>90% (B)</p> Signup and view all the answers

What is the treatment for acute symptomatic cholecystitis?

<p>Laparoscopic cholecystectomy (C)</p> Signup and view all the answers

What is the goal of source control in secondary peritonitis?

<p>Surgical debridement and drainage (C)</p> Signup and view all the answers

What is often the underlying cause of cholangitis and cholecystitis?

<p>Obstruction (B)</p> Signup and view all the answers

Which of the following antimicrobial agents is recommended for the initial treatment of CAPD-associated peritonitis due to gram-positive organisms?

<p>Vancomycin (D)</p> Signup and view all the answers

What is the recommended treatment for MSSA in CAPD-associated peritonitis?

<p>Cefazolin (C)</p> Signup and view all the answers

Which of the following antibiotics is recommended as an alternative for gram-negative coverage in patients with severe IgE-mediated penicillin allergy or intolerance to β-lactams?

<p>Aztreonam (C)</p> Signup and view all the answers

What is the treatment of choice for Enterococcus species or Streptococcus species in CAPD-associated peritonitis?

<p>Ampicillin (C)</p> Signup and view all the answers

Which of the following antimicrobial agents is recommended for the treatment of P. aeruginosa in CAPD-associated peritonitis?

<p>All of the above (D)</p> Signup and view all the answers

What is the recommended treatment for refractory peritonitis caused by MRSA in CAPD-associated peritonitis?

<p>Vancomycin (B)</p> Signup and view all the answers

What is the recommended treatment for Vancomycin Resistant enterococcus (VRE)?

<p>Linezolid, quinupristin–dalfopristin, or daptomycin (C)</p> Signup and view all the answers

What type of antifungal drugs are considered the drugs of choice empirically?

<p>Echinocandins (D)</p> Signup and view all the answers

What is the primary goal of therapy for secondary peritonitis?

<p>All of the above (D)</p> Signup and view all the answers

Which antifungal drug is the drug of choice for C. albicans?

<p>Fluconazole (B)</p> Signup and view all the answers

What is the primary concern associated with using conventional amphotericin B?

<p>Toxicity (D)</p> Signup and view all the answers

What is the recommended empiric monotherapy for mild-to-moderate community-acquired infections?

<p>Ertapenem, moxifloxacin, or cefoxitin (D)</p> Signup and view all the answers

What is the significance of timely source control with surgical intervention in secondary peritonitis?

<p>It improves clinical success (A)</p> Signup and view all the answers

What is a characteristic of intra-abdominal abscesses?

<p>They contain mixed infections involving E. coli or enterococci with B. fragilis (D)</p> Signup and view all the answers

What is the recommended treatment for intra-abdominal abscesses?

<p>Piperacillin–tazobactam 3.375 g IV every 6 hours (C)</p> Signup and view all the answers

What is the recommended time frame for administering antibiotics in patients with septic shock?

<p>Within 1 hour of presentation (A)</p> Signup and view all the answers

What type of antibiotics should be used in patients with penetrating trauma to the abdomen?

<p>Antibiotics active against both aerobic and anaerobic pathogens (A)</p> Signup and view all the answers

What is the current recommendation for the use of tigecycline as an empiric agent to treat patients with IAI?

<p>It is not recommended (C)</p> Signup and view all the answers

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