Integument Microanatomy- Pt 1
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Questions and Answers

Which is not a major function of the skin?

  • Calcium homeostasis
  • Protection against physical, chemical, and biological agents
  • Energy storage
  • Hair growth (correct)
  • What is the dermal layer composed of?

  • Stratified keratinized epithelium
  • A and C
  • Loose connective tissue and dense irregular connective tissue (correct)
  • None of the above
  • What is the percentage of body weight that the skin composes?

  • 2-4%
  • 30-40%
  • 20-25%
  • 8-16% (correct)
  • What is the characteristic of thin skin?

    <p>Hair follicles, thin epidermis layer, sebaceous glands, and apocrine sweat glands</p> Signup and view all the answers

    What is the embryological origin of the dermis?

    <p>Mesoderm</p> Signup and view all the answers

    What is composed of stratified keratinized epithelium?

    <p>Epidermis</p> Signup and view all the answers

    What is unique about the Stratum spinosum layer?

    <p>It has a spiny appearance due to tonofilaments and desmosomes</p> Signup and view all the answers

    What is the main function of the Stratum basale layer?

    <p>To anchor the epidermis to the dermis</p> Signup and view all the answers

    What is the Stratum granulosum layer?

    <p>A layer that is alive but non-active</p> Signup and view all the answers

    What is the main difference between thin and thick skin in terms of the Stratum spinosum layer?

    <p>The number of cell layers</p> Signup and view all the answers

    What is the role of the dermal papillae?

    <p>To attach the dermis to the epidermis</p> Signup and view all the answers

    What is the order of the layers of the epidermis from deep to superficial?

    <p>Stratum basale, Stratum spinosum, Stratum granulosum, Stratum lucidum, Stratum corneum</p> Signup and view all the answers

    What is the characteristic of the Stratum spinosum layer in terms of cell division?

    <p>It only divides when needed</p> Signup and view all the answers

    What percentage of cells in the epidermal layer are composed of keratinocytes?

    <p>95%</p> Signup and view all the answers

    Which type of cell in the epidermis acts as a mechanoreceptor?

    <p>Merkel's cells</p> Signup and view all the answers

    What is the primary function of melanocytes in the epidermis?

    <p>UV protection</p> Signup and view all the answers

    From which embryonic layer is the epidermis derived?

    <p>Ectoderm</p> Signup and view all the answers

    What of the following is commonly found in the hypodermis?

    <p>Panniculus adiposus</p> Signup and view all the answers

    Where are dermo-epidermal junctions typically found?

    <p>Areas subjected to traction</p> Signup and view all the answers

    What is the main function of lamellar granules in the stratum granulosum?

    <p>To form a waterproof lipid sheet called intercellular cement</p> Signup and view all the answers

    What is the composition of the stratum corneum?

    <p>Consists entirely of keratin</p> Signup and view all the answers

    What is eleidin in the stratum lucidum layer?

    <p>It is a protein that is chemically related to keratin</p> Signup and view all the answers

    What is the characteristic of the stratum lucidum?

    <p>It is always deceased</p> Signup and view all the answers

    What is the location of the stratum granulosum?

    <p>It is the layer where cells begin to flatten</p> Signup and view all the answers

    What is the thickness of the stratum granulosum?

    <p>It is typically 3-5 cells thick</p> Signup and view all the answers

    What is the characteristic of the stratum corneum?

    <p>It is constantly being shed at the surface</p> Signup and view all the answers

    What is arrow "A" pointing to in this image?

    <p>Papillary layer</p> Signup and view all the answers

    What is arrow "B" pointing to in this image?

    <p>Reticular layer</p> Signup and view all the answers

    What is arrow "A" pointing to in this image of the dermo-epidermal junction?

    <p>Epidermal pegs/ridges</p> Signup and view all the answers

    What is arrow "B" pointing to in this image of the dermo-epidermal junction?

    <p>Dermal papilla</p> Signup and view all the answers

    Which epidermal layer is the arrow referring to in this image?

    <p>Stratum spinosum</p> Signup and view all the answers

    Which epidermal layer is the arrow referring to in this image?

    <p>Stratum granulosum</p> Signup and view all the answers

    Which epidermal layer is the arrow referring to in this image?

    <p>Stratum lucidum</p> Signup and view all the answers

    Which epidermal layer is the arrow referring to in this image?

    <p>Stratum corneum</p> Signup and view all the answers

    What is the arrow pointing to in this epidermal picture?

    <p>Desmosomes</p> Signup and view all the answers

    Which type of skin is depicted in this picture?

    <p>Thick skin</p> Signup and view all the answers

    Which type of skin is depicted in this picture?

    <p>Thin skin</p> Signup and view all the answers

    What is depicted at number 7 within this epidermal image?

    <p>Epidermal peg</p> Signup and view all the answers

    What is the letter "A" referring to in this picture of skin?

    <p>Hair follicle</p> Signup and view all the answers

    What is the letter "C" referring to in this picture of skin?

    <p>Hair bulb</p> Signup and view all the answers

    What is the letter "D" referring to in this picture of skin?

    <p>Dermis</p> Signup and view all the answers

    What is the letter "E" referring to in this picture of skin?

    <p>Sebaceous gland</p> Signup and view all the answers

    What is the letter "G" referring to in this picture of skin?

    <p>Apocrine sweat gland</p> Signup and view all the answers

    What is the letter "F" referring to in this picture of skin?

    <p>Hair shaft</p> Signup and view all the answers

    Study Notes

    Integument: General Info

    • Collagen dysplasia is an example of an integumental disease.
    • Integument is the composition of skin and epidermal derivatives.
    • Epidermal derivatives include: foot pads, claws, horns, hooves, glands (like anal sacs), uropygial glands, wattles, combs, spurs, and feathers.

    Skin: General Info

    • Skin is the largest organ in the body, composing 8-16% of body weight.
    • Skin functions include: protection, prevent water and electrolyte loss, calcium homeostasis, temperature regulation, sensation, energy storage, and immune functions.

    Skin Types

    • Thick skin: hairless, thick epidermis layer, merocrine/eccrine sweat glands. Examples: paw pads and muzzles.
    • Thin skin: hair follicles (often with arrector pili muscles), thin epidermis layer, sebaceous glands, and apocrine sweat glands.

    Skin: Composition

    • Skin is composed of the epidermal layer, dermal layer, and hypodermal layer.
    • Dermal layer can be further subdivided into the papillary layer (loose connective tissue) and reticular layer (dense irregular connective tissue).

    Epidermis

    • Epidermis is an avascular, thick barrier of epithelium composed of stratified keratinized epithelium.
    • Keratinocytes compose 95% of cells in the epidermal layer.
    • Non-keratinocytes found in the epidermis include: Langerhans cells (immune function as a tissue macrophage), Merkel's cells (mechanoreceptors), and melanocytes (UV protection).

    Dermis

    • Dermis is composed of blood vessels, connective tissue, and nervous tissue.
    • Dermis functions to support the epidermis.
    • Things found in the dermal layer include: blood vessels, collagen fibers, elastic fibers, resident cells, transient cells, nerves, and lymphatics.

    Hypodermis (Subcutis)

    • Hypodermis contains panniculus adiposus, which is loose connective tissue that's rich in adipocytes.
    • Hypodermal layer is located beneath the dermis.

    Dermo-Epidermal Junction

    • Dermo-epidermal junction is the interface between the dermis and epidermis.
    • Examples of where dermo-epidermal junctions can be found include: footpads, nasal planum, scrotum, and areas subjected to traction.

    Epidermal Pegs/Ridges and Dermal Papilla

    • Epidermal pegs/ridges: downward projections of the deep epidermis into the dermis.
    • Dermal papilla: upward projections of superficial dermis that bring blood supply closer to the epithelium.

    Epidermis: Layers

    • Stratum basale: active, alive, cuboidal to columnar epithelium, keratinocytes, and melanocytes.
    • Stratum spinosum: active, alive, polygonal, cohesive, and resistant to abrasion.
    • Stratum granulosum: alive, but non-active, contains basophilic keratohyalin granules, and lamellar granules.
    • Stratum lucidum: not always present, deceased, translucent, and contains desmosome, many keratin filaments, and cytoplasm with eleidin.
    • Stratum corneum: deceased, outermost epidermal layer, contains up to 20 cell layers, lacks nuclei and organelles, and consists entirely of keratin.

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    Description

    This quiz covers the basics of the integumentary system, including the composition of skin, epidermal derivatives, and the functions of skin. Learn about collagen dysplasia and other integumental diseases.

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