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Questions and Answers
What two main tissue types make up the dermis?
What two main tissue types make up the dermis?
Areolar and dense connective tissue.
What are the two structures that create the uneven border between the dermis and epidermis?
What are the two structures that create the uneven border between the dermis and epidermis?
Epidermal ridges and dermal papillae.
What is the function of the collagen and elastic fibers found within the dermis?
What is the function of the collagen and elastic fibers found within the dermis?
They provide toughness and elasticity to the skin.
Besides nutrients, what else do the dermal blood vessels help regulate?
Besides nutrients, what else do the dermal blood vessels help regulate?
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What genetically determined feature, formed by dermal papillae, creates unique fingerprints?
What genetically determined feature, formed by dermal papillae, creates unique fingerprints?
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What two main layers compose the skin?
What two main layers compose the skin?
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What type of tissue makes up the epidermis?
What type of tissue makes up the epidermis?
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What is the main function of the subcutaneous layer (hypodermis)?
What is the main function of the subcutaneous layer (hypodermis)?
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What is the deepest layer of the epidermis called, and what is its key characteristic?
What is the deepest layer of the epidermis called, and what is its key characteristic?
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What are keratinocytes?
What are keratinocytes?
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What is the process called by which keratinocytes harden and die as they move toward the skin's surface?
What is the process called by which keratinocytes harden and die as they move toward the skin's surface?
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What are three functions of the epidermis?
What are three functions of the epidermis?
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What structure, within the skin, provides nourishment to the stratum basale of the epidermis?
What structure, within the skin, provides nourishment to the stratum basale of the epidermis?
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What is the actively growing region of the nail called?
What is the actively growing region of the nail called?
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What is the substance that makes up nails and hair?
What is the substance that makes up nails and hair?
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Where do hair follicles extend down into skin?
Where do hair follicles extend down into skin?
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What part of the hair follicle is the deepest?
What part of the hair follicle is the deepest?
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Are the cells that make up the hair shaft living or dead?
Are the cells that make up the hair shaft living or dead?
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Which layer of the epidermis is only found in the thick skin of the palms and soles?
Which layer of the epidermis is only found in the thick skin of the palms and soles?
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What is the main function of melanin in skin cells?
What is the main function of melanin in skin cells?
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What are the two types of melanin and what are their colors?
What are the two types of melanin and what are their colors?
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What is the name of the layer of the epidermis that is considered the innermost, dividing layer?
What is the name of the layer of the epidermis that is considered the innermost, dividing layer?
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What is the name of the outermost layer of the epidermis composed of dead, flattened, keratinized cells?
What is the name of the outermost layer of the epidermis composed of dead, flattened, keratinized cells?
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What causes the skin to appear blue, a condition called cyanosis?
What causes the skin to appear blue, a condition called cyanosis?
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Besides genetic factors, what other factors influence skin color?
Besides genetic factors, what other factors influence skin color?
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What type of cells produce melanin?
What type of cells produce melanin?
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What is the primary function of the arrector pili muscle in the skin?
What is the primary function of the arrector pili muscle in the skin?
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How does sebum, secreted by sebaceous glands, benefit the hair and skin?
How does sebum, secreted by sebaceous glands, benefit the hair and skin?
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What are the two main types of sweat glands, and how do their functions differ?
What are the two main types of sweat glands, and how do their functions differ?
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What is the role of melanin in skin and hair?
What is the role of melanin in skin and hair?
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Explain how the skin helps regulate body temperature in response to overheating.
Explain how the skin helps regulate body temperature in response to overheating.
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Describe how the skin helps regulate body temperature in response to extreme cooling.
Describe how the skin helps regulate body temperature in response to extreme cooling.
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What is the first step in the healing process of a deep wound?
What is the first step in the healing process of a deep wound?
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What is the role of fibroblasts in the healing of a deep wound?
What is the role of fibroblasts in the healing of a deep wound?
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What are granulations in the context of wound healing?
What are granulations in the context of wound healing?
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What are the four characteristics of inflammation and their causes?
What are the four characteristics of inflammation and their causes?
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Besides protection, what are three other key functions of the skin?
Besides protection, what are three other key functions of the skin?
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What is the specific name for glands that secrete earwax and what is its function?
What is the specific name for glands that secrete earwax and what is its function?
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What is the difference between eumelanin and pheomelanin in hair?
What is the difference between eumelanin and pheomelanin in hair?
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What are the common causes of albinism and gray hair?
What are the common causes of albinism and gray hair?
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What is the role of the hypothalamus in skin temperature regulation
What is the role of the hypothalamus in skin temperature regulation
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Flashcards
Hair Shaft
Hair Shaft
The outermost, visible part of a hair, formed from dead, keratinized cells.
Hair Follicle
Hair Follicle
A tube-like structure in the skin that encloses a hair root. It dips into the dermis or subcutaneous layer.
Hair Bulb
Hair Bulb
The deepest part of the hair root at the base of the hair follicle where new hair cells are formed.
Lunula
Lunula
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Nail Plate
Nail Plate
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Dermis
Dermis
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Dermal Papillae
Dermal Papillae
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Dermal Blood Vessels
Dermal Blood Vessels
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Dermis Structures
Dermis Structures
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Dermis Elasticity
Dermis Elasticity
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Stratum Corneum
Stratum Corneum
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Stratum Basale
Stratum Basale
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Stratum Lucidum
Stratum Lucidum
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Stratum Granulosum
Stratum Granulosum
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Stratum Spinosum
Stratum Spinosum
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Melanocytes
Melanocytes
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Melanin
Melanin
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Pheomelanin
Pheomelanin
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Skin
Skin
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Epidermis
Epidermis
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Keratinization
Keratinization
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Keratin
Keratin
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Subcutaneous layer (Hypodermis)
Subcutaneous layer (Hypodermis)
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Temperature Regulation by Dermal Blood Vessels
Temperature Regulation by Dermal Blood Vessels
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Holocrine secretion
Holocrine secretion
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Eccrine sweat glands
Eccrine sweat glands
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Apocrine sweat glands
Apocrine sweat glands
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Sebum
Sebum
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Sudoriferous glands
Sudoriferous glands
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Arrector pili muscle
Arrector pili muscle
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Merocrine secretion
Merocrine secretion
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Vasodilation
Vasodilation
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Vasoconstriction
Vasoconstriction
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Sudomotor activity
Sudomotor activity
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Hypothermia
Hypothermia
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Hyperthermia
Hyperthermia
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Study Notes
Integumentary System, Skin
- Skin is the largest organ in the body by weight.
- Accessory structures include hair, nails, glands, and sensory receptors.
- The integumentary system consists of the skin and its accessory structures.
- Skin acts as a barrier between the internal and external environments.
- Skin has two layers: epidermis and dermis.
- Epidermis: thin, outer layer of stratified squamous epithelium.
- Dermis: thicker, inner layer of connective tissue, blood vessels, smooth muscle, and nervous tissue.
- Subcutaneous layer (hypodermis): layer under the dermis, consisting of areolar and adipose tissues; binds skin to underlying tissues, but is not part of the skin. Adipose tissue insulates to conserve body heat.
Learning Objectives
- Describe the five layers (strata) of the epidermis.
- Differentiate between thick skin and thin skin.
- Explain what causes differences in skin color.
- Characterize the two layers of the dermis.
- Describe how dermal blood vessels function in temperature regulation.
- List the functions of the skin.
- Name ways in which the epidermis protects the body and prevents water loss.
- Describe the integument's healing process for deep wounds.
Layers of the Skin and Hypodermis
- The epidermis has 4 or 5 layers depending on if the skin is thin or thick.
- Stratum basale: innermost layer, a dividing layer
- Stratum spinosum
- Stratum granulosum
- Stratum corneum: outermost layer; dead, flattened, keratinized cells
- Stratum lucidum: layer between the stratum granulosum and the stratum corneum; only in thick skin
Epidermis
- Consists of stratified squamous epithelium.
- Lacks blood vessels.
- Consists of 4 layers in thin skin, 5 layers in thick skin.
- Stratum basale (germinativum): deepest layer, dividing cells; well-nourished by dermal blood vessels.
- Basal cells divide, older cells become keratinocytes (due to keratin accumulation),migrate to the surface, harden, dehydrate, and die (keratinization).
Epidermis (Continued)
- Protects against water loss, mechanical injury, chemicals, and microorganisms.
- Stratum basale (innermost): dividing layer.
- Stratum spinosum
- Stratum granulosum.
- Stratum corneum (outermost): dead, flattened, keratinized cells continually shed. Only in thick skin (palms and soles) is the stratum lucidum.
Skin Color
- All people have about the same number of melanocytes.
- Skin color is genetically determined and involves the amount of melanin produced by melanocytes.
- Genetic, environmental, and physiological factors influence it.
- Melanin production differences and granule size/distribution influence skin tone.
- UV exposure increases melanin, darkening the skin.
- Blood circulation, oxygenation affect skin tone. Well-oxygenated blood (pink); poorly oxygenated blood (blue - cyanosis).
- Yellowish skin can indicate carotene intake (from orange foods). Jaundice can be a symptom of liver disease.
The Dermis
- Binds the epidermis to underlying tissues; uneven border.
- Epidermal ridges (extend down toward dermis) and dermal papillae (extend up toward epidermis) create uneven border.
- Genetically determined pattern of friction ridges forms fingerprints.
- Dermis consists of areolar and dense connective tissues, collagen and elastic fibers in a gel-like ground substance.
- Provides toughness and elasticity to skin.
- Dermal blood vessels carry nutrients to upper layers, regulate temperature.
- Dermis contains nerve fibers, sensory receptors, hair follicles, sebaceous/sweat glands.
Accessory Structures
- Nails - protective coverings over fingertips and toes. -Nail plate over nail bed -Lunula: half-moon-shaped active region at base of nail plate. -Keratin in nails is harder than skin surface keratin.
- Hair can be found in most areas of skin (not palms, soles, lips etc.) -Epithelial stem cells form the hair follicle -Hair follicles dip into dermis/subcutaneous layer -Hair bulb: the deepest part of the hair root, near where cells divide for new hair growth. -Old cells form the keratinized hair shaft. -Hair is comprised of keratinized epithelial cells.
- Glands -Sebaceous glands (holocrine): associated with hair follicles; secrete sebum (oil). Sebum waterproofs and moisturizes hair and skin, preventing water loss. -Sweat glands (sudoriferous): two types of sweat glands Eccrine (merocrine): respond to body temperature; more abundant than apocrine glands; secrete onto the skin surface. Apocrine (merocrine): become active at puberty; respond to stress/sexual arousal; found in the axilla and groin; sweat contains proteins/fats that produce body odor; secrete into hair follicles. -Modified sweat glands Ceruminous glands: secrete wax in ear canal; trap dust/pathogens Mammary glands: secrete milk to nourish a baby.
Skin Functions
- Important for maintaining homeostasis.
- Protective covering; prevents substances and pathogens from entering.
- Waterproof; slows down water loss.
- Melanin pigment protects against UV radiation.
- Houses sensory receptors (for touch, pressure, pain, temperature).
- Excretes wastes
- Conducts part of the vitamin D production process.
- Regulates body temperature (sweat activation/vasodilation/vasoconstriction of blood vessels)
- Protection of underlying tissues.
Role of Skin in Body Temperature Regulation
- Proper temperature regulation is vital for metabolic reactions.
- Skin plays a major role regulated by the hypothalamus.
- Active cells, such as those of the heart and skeletal muscle, produce heat.
- Heat may be lost to the surroundings from skin through radiation.
- Responses to excess heat (hyperthermia): vasodilation, sweat activation.
- Responses to excess cooling (hypothermia): vasoconstriction, sweat gland inactivation, shivering
Healing of Wounds
- Inflammation (dilation and permeability of blood vessels) is normal bodily response to injury.
- Dilated blood vessels/fluids bring in oxygen, nutrients, and immune cells to aid in repair.
- Superficial cuts heal by epithelial cell reproduction. Deeper injuries require more complex response, including:
- Blood clot formation.
- Scab formation.
- Fibroblast migration, collagen fiber secretion for wound edge binding.
- Phagocytic cell removal of dead/damaged cells.
- Tissue replacement with new tissue and scab shedding
- Extensive collagen fiber production can create elevated scar tissue in large wounds.
- Granulation formation/healing (rounded masses in large wounds) via new blood vessel formation + fibroblast activity + collagen production.
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Description
Test your knowledge on the integumentary system, focusing on the skin and its accessory structures. This quiz covers the layers of the skin, their functions, and the characteristics of the epidermis and dermis. Challenge yourself to differentiate between various skin types and understand skin color variations.