Insulin Modelling
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Questions and Answers

What is the role of insulin in glucose regulation?

Insulin stimulates glucose uptake by peripheral tissues and inhibits hepatic glucose output.

Where is insulin secreted from?

Insulin is secreted from the beta-cells located in the islets of Langerhans in the pancreas.

What is the most important stimulus for insulin secretion?

Glucose is the most important stimulus for insulin secretion.

What role does deficient insulin secretion play in diabetes mellitus?

<p>Deficient insulin secretion plays a major role in the development of diabetes mellitus.</p> Signup and view all the answers

What has a large research effort been devoted to in relation to beta-cell function?

<p>A large research effort has been devoted to studying beta-cell function in health and disease.</p> Signup and view all the answers

What is the function of insulin in the body?

<p>Insulin stimulates glucose uptake by peripheral tissues and inhibits hepatic glucose output.</p> Signup and view all the answers

Where are beta-cells located in the pancreas?

<p>Beta-cells are located in the endocrine part of the pancreas in microorgans called islets of Langerhans.</p> Signup and view all the answers

What is the main stimulus for insulin secretion?

<p>Glucose is the physiologically most important stimulus for insulin secretion.</p> Signup and view all the answers

What is the role of mathematical models in studying beta-cell function?

<p>Mathematical models have been used to obtain insight from data ranging from single beta-cells to clinical measurements.</p> Signup and view all the answers

What is the focus of research in relation to beta-cell function and diabetes mellitus?

<p>The focus of research is on the role of deficient insulin secretion in the development of diabetes mellitus.</p> Signup and view all the answers

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