Insulin and Metabolic Regulation Quiz

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Questions and Answers

Which enzyme is predominantly responsible for the dephosphorylation of synthase b to synthase a?

  • Phosphoprotein phosphatase-4 (PP-4)
  • Phosphoprotein phosphatase-2 (PP-2)
  • Phosphoprotein phosphatase-1 (PP-1) (correct)
  • Phosphoprotein phosphatase-3 (PP-3)

What is the effect of insulin on the activity of PP-1?

  • Increases it (correct)
  • Has no effect on it
  • Decreases it
  • Inhibits it

What is the role of glucagon and epinephrine in relation to the activity of PP-1?

  • Increases it
  • Decreases it (correct)
  • Inhibits it
  • Has no effect on it

What is the primary function of insulin in relation to glucose uptake?

<p>Increases glucose uptake (C)</p> Signup and view all the answers

What is the effect of phosphorylation on synthase b?

<p>Inhibits it (A)</p> Signup and view all the answers

What is the effect of dephosphorylation on synthase a?

<p>Activates it (A)</p> Signup and view all the answers

What is the common factor between the dephosphorylation of synthase b and phosphorylase?

<p>Phosphoprotein phosphatase-1 (PP-1) (A)</p> Signup and view all the answers

What is the effect of glucagon and epinephrine on the uptake of glucose from the blood?

<p>Decreases it (B)</p> Signup and view all the answers

What is the effect of insulin on the conversion of synthase b to synthase a?

<p>Activates it (C)</p> Signup and view all the answers

What is the effect of glucagon and epinephrine on the conversion of synthase b to synthase a?

<p>Inhibits it (D)</p> Signup and view all the answers

Which enzyme is predominantly responsible for the dephosphorylation of synthase b to synthase a?

<p>Phosphoprotein phosphatase-1 (PP-1) (C)</p> Signup and view all the answers

What is the effect of insulin on the activity of PP-1?

<p>Increases it (B)</p> Signup and view all the answers

What is the role of glucagon and epinephrine in relation to the activity of PP-1?

<p>Decreases it (B)</p> Signup and view all the answers

What is the primary function of insulin in relation to glucose uptake?

<p>Increases glucose uptake (B)</p> Signup and view all the answers

What is the effect of phosphorylation on synthase b?

<p>Inhibits it (A)</p> Signup and view all the answers

What is the effect of dephosphorylation on synthase a?

<p>Activates it (A)</p> Signup and view all the answers

What is the common factor between the dephosphorylation of synthase b and phosphorylase?

<p>Phosphoprotein phosphatase-1 (PP-1) (D)</p> Signup and view all the answers

What is the effect of glucagon and epinephrine on the uptake of glucose from the blood?

<p>Decreases it (A)</p> Signup and view all the answers

What is the effect of insulin on the conversion of synthase b to synthase a?

<p>Activates it (A)</p> Signup and view all the answers

What is the effect of glucagon and epinephrine on the conversion of synthase b to synthase a?

<p>Inhibits it (D)</p> Signup and view all the answers

Which enzyme predominately carries out the dephosphorylation required for the reconversion of synthase b to synthase a?

<p>Phosphoprotein phosphatase-1 (D)</p> Signup and view all the answers

Which other enzyme is also dephosphorylated by PP-1?

<p>Phosphorylase (A)</p> Signup and view all the answers

What is the opposing effect of insulin in relation to glucagon and epinephrine?

<p>It increases the uptake of glucose from the blood (A)</p> Signup and view all the answers

What is the role of glucagon and epinephrine in relation to glucose uptake?

<p>They decrease the uptake of glucose from the blood (D)</p> Signup and view all the answers

What is the effect of dephosphorylation on synthase b?

<p>It converts synthase b to synthase a (A)</p> Signup and view all the answers

Which enzyme is involved in the phosphorylation of synthase b?

<p>Phosphoprotein kinase (D)</p> Signup and view all the answers

What is the role of insulin in relation to PP-1 activity?

<p>It activates PP-1 activity (D)</p> Signup and view all the answers

What is the effect of glucagon and epinephrine on PP-1 activity?

<p>They inhibit PP-1 activity (B)</p> Signup and view all the answers

What is the role of phosphorylation in the regulation of synthase activity?

<p>It inhibits synthase b (B)</p> Signup and view all the answers

Which enzyme is responsible for the phosphorylation of synthase a?

<p>Phosphoprotein kinase (B)</p> Signup and view all the answers

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