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Innate Immunity Details Quiz

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Questions and Answers

Which of the following best describes one of the physical barriers of innate immunity?

Increased vascular permeability in the lungs

Production of acute phase proteins in mucosal surfaces

Presence of intraepithelial lymphocytes (correct)

Secretion of interleukin-1 by the skin

What is the main function of lysozyme in innate immunity?

Increases vascular permeability

Breaks down peptidoglycan in bacteria (correct)

Stimulates production of acute phase proteins

Traps pathogens for removal in mucosal surfaces

Which protein effector found in skin and mucosal secretions is involved in the innate immune response?

Interleukin-6

Transferrin

Complement

Antimicrobial peptides (defensins & cathelicidins) (correct)

How do neutrophils and macrophages kill bacteria within the phagolysosome?

Via the oxidative burst involving oxygen and nitrogen radicals Signup and view all the answers

What is the role of an activated macrophage in the innate immune response?

Recognition of non-self through PAMPs and other structures Signup and view all the answers

What is the function of Interleukin-8 (IL-8) in the immune response?

Attraction/activation of neutrophils Signup and view all the answers

Which molecule is responsible for activating NK cells and influencing lymphocyte differentiation?

Interleukin-12 (IL-12) Signup and view all the answers

What is the primary function of Tumor necrosis factor-α (TNF-α) in the immune response?

Increased permeability of vascular endothelium Signup and view all the answers

In the context of non-specific phagocytic cells recognizing foreign tissue, what is the role of PRR (Pattern Recognition Receptor)?

To recognize the foreignness of objects in a general way Signup and view all the answers

What is the significance of non-specific phagocytic cells wandering through the body?

They randomly come in contact with foreign tissue Signup and view all the answers