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Innate Immune System Quiz

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Questions and Answers

Which of the following is true regarding the innate immune response to microbes?

It is not required for the activation of antigen-specific lymphocytes

It generates molecules that provide signals to activate naive T and B lymphocytes (correct)

It only serves as a warning function to the adaptive immune system

It does not play a role in host defense

What is the role of danger signals in the activation of lymphocytes?

To generate molecules that provide signals

To ensure that lymphocytes respond to infectious agents and not to harmless substances (correct)

To provide signals in addition to antigens

To activate naive T and B lymphocytes

What is the purpose of adjuvants in inducing adaptive immune responses?

To elicit the same innate immune reactions as microbes do (correct)

To suppress the innate immune response to microbes

To provide antigens for the activation of lymphocytes

To generate danger signals to activate lymphocytes

What is the function of costimulators in T cell activation?

Costimulators are surface molecules on dendritic cells that bind to receptors on T cells to activate them Signup and view all the answers

What is the role of C3d in B cell differentiation?

C3d is a microbial antigen recognized by B cells to initiate the process of differentiation into antibody-secreting cells Signup and view all the answers

What is the main function of second signals in adaptive immunity?

To guide the nature of the adaptive immune response Signup and view all the answers

What is the two-signal requirement for lymphocyte activation?

Antigen recognition by lymphocytes provides signal 1 for activation of the lymphocytes and substances produced during innate immune responses to microbes provide signal 2 Signup and view all the answers

Which of the following is a function of innate immune responses in addition to host defense?

Providing signals to activate naive T and B lymphocytes Signup and view all the answers

What is the purpose of the two-signal requirement for full activation of antigen-specific lymphocytes?

To ensure lymphocytes respond to infectious agents and not to harmless, noninfectious substances Signup and view all the answers

What is the role of danger signals in the activation of adaptive immune responses?

To warn the adaptive immune system that it needs to respond Signup and view all the answers

What is the covalently attached protein to microbes that serves as the second signal for humoral immune responses?

C3b Signup and view all the answers

What type of immunity is best able to combat blood-borne microbes?

Humoral immunity Signup and view all the answers

What is the main function of cytokines such as IL-12, IL-1, and IL-6 in the activation of T lymphocytes?

Stimulate the differentiation of naive T cells into effector cells Signup and view all the answers

What is the role of second signals in adaptive immunity?

Guide the nature of the adaptive immune response Signup and view all the answers