25 Questions
When does tolerance to self-molecules and cells develop during the development of the immune repertoire?
At the beginning of the process
What is the initial focus of immune repertoire development?
Developing tolerance to self-molecules and cells
Which aspect of immunity is prioritized first during immune repertoire development?
Tolerance to self-molecules and cells
What is the sequence of events in the early stages of immune repertoire development?
Tolerance to self-molecules and cells, antibody production, T cell activation
What role does tolerance to self-molecules and cells play in immune system development?
It is crucial for preventing autoimmune reactions
What is a characteristic of T-independent antigens?
They stimulate specific immunoglobulin production without the need for T cells
Why do T-independent antigens not require T cells for immunoglobulin production?
They directly stimulate B cells without needing T cell signals
How do T-independent antigens differ from T-dependent antigens in terms of stimulation?
T-independent antigens activate B cells directly without T cell involvement
Which statement accurately describes the role of T-independent antigens in immunoglobulin production?
They circumvent the need for T cell help in antibody production
In the context of immunological response, what distinguishes T-independent antigens from T-dependent antigens?
T-independent antigens trigger B cell activation without needing signals from helper T cells
What type of antigens are Pneumococcal polysaccharide, lipopolysaccharide, and Flagella classified as?
T cell independent (TI) antigens
How does the immune response vary for T cell independent (TI) antigens on each exposure?
It tends to be similar on each exposure
Which of the following is NOT an example of a T cell independent (TI) antigen?
Influenza virus protein coat
What distinguishes T cell independent (TI) antigens from T cell-dependent (TD) antigens?
TI antigens do not require T cells for activation
How do T cell independent (TI) antigens typically elicit an immune response?
By directly activating B cells without the help of T cells
What is the main difference between innate and adaptive immunity in terms of specificity?
Innate immunity is specific for microbial antigens, while adaptive immunity is specific for both microbial and nonmicrobial antigens.
What is the characteristic of adaptive immunity that is not mentioned for innate immunity?
Memory
What are tolerogens?
Antigens (usually self) that induce immune unresponsiveness under normal conditions.
What is the characteristic of innate immunity that is not mentioned for adaptive immunity?
Tolerance to antigens
Based on the information provided, which of the following statements is correct?
Adaptive immunity has a broader specificity than innate immunity.
What is the main idea conveyed in the given text?
The immune system does not attack self-tissues in a normal, healthy state.
What can be inferred from the text regarding the immune system's function?
It distinguishes between self and non-self molecules.
Which of the following statements is NOT supported by the given text?
The immune system is inactive in a healthy state.
What can be inferred about the presence of an immune response against self-tissues?
It is an indication of an underlying health condition.
Based on the text, which of the following statements is true?
The immune system protects the body from self-attack.
Explore the characteristics of innate and adaptive immunity, including specificity, diversity, memory, and tolerance to antigens. Learn about the differences between these two immune responses.
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