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Questions and Answers
What is the term for the pattern where a dominant allele is present but its effect is not visible?
What is the term for the pattern where a dominant allele is present but its effect is not visible?
In a case of incomplete dominance, what is the phenotype of the heterozygous offspring?
In a case of incomplete dominance, what is the phenotype of the heterozygous offspring?
What is the term for the situation where the heterozygote has a more beneficial trait than either homozygote?
What is the term for the situation where the heterozygote has a more beneficial trait than either homozygote?
What is the reason for penetrance, according to the molecular perspective?
What is the reason for penetrance, according to the molecular perspective?
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What is the term for the pattern where the heterozygote expresses both alleles simultaneously without forming an intermediate phenotype?
What is the term for the pattern where the heterozygote expresses both alleles simultaneously without forming an intermediate phenotype?
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Why may heterozygotes have increased resistance to infection by microorganisms?
Why may heterozygotes have increased resistance to infection by microorganisms?
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What is the result of a cross between homozygous red-flowered and homozygous white-flowered parents, in terms of flower color?
What is the result of a cross between homozygous red-flowered and homozygous white-flowered parents, in terms of flower color?
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In dominant and recessive alleles, what is the main difference between the dominant and recessive alleles?
In dominant and recessive alleles, what is the main difference between the dominant and recessive alleles?
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What is a characteristic of simple Mendelian inheritance?
What is a characteristic of simple Mendelian inheritance?
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What is the main goal of examining different patterns of Mendelian inheritance?
What is the main goal of examining different patterns of Mendelian inheritance?
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What is the term applied to the inheritance of alleles that obey Mendel's laws and follow a strict dominant/recessive relationship?
What is the term applied to the inheritance of alleles that obey Mendel's laws and follow a strict dominant/recessive relationship?
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What can occur when a single gene has three or more alleles?
What can occur when a single gene has three or more alleles?
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What is the result of a single copy of a dominant allele in a heterozygote?
What is the result of a single copy of a dominant allele in a heterozygote?
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What is an example of a complex inheritance pattern?
What is an example of a complex inheritance pattern?
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What is the relationship between genetic polymorphism and Mendelian inheritance?
What is the relationship between genetic polymorphism and Mendelian inheritance?
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What is the result of a mutation in a gene?
What is the result of a mutation in a gene?
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What is the blood type of an individual carrying the A and B alleles?
What is the blood type of an individual carrying the A and B alleles?
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In X-linked inheritance, what percentage of the protein produced by a single copy of the dominant allele is sufficient to produce the dominant trait in a heterozygous female?
In X-linked inheritance, what percentage of the protein produced by a single copy of the dominant allele is sufficient to produce the dominant trait in a heterozygous female?
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What type of inheritance pattern involves the effect of sex on the phenotype of the individual?
What type of inheritance pattern involves the effect of sex on the phenotype of the individual?
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Which type of inheritance pattern involves traits that occur in only one of the two sexes?
Which type of inheritance pattern involves traits that occur in only one of the two sexes?
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What is the main difference between sex-influenced and sex-limited inheritance patterns?
What is the main difference between sex-influenced and sex-limited inheritance patterns?
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In X-linked inheritance, what is the expression of the copy of the gene that males carry?
In X-linked inheritance, what is the expression of the copy of the gene that males carry?
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What is an example of codominance?
What is an example of codominance?
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What regulates the molecular expression of genes in sex-influenced and sex-limited inheritance patterns?
What regulates the molecular expression of genes in sex-influenced and sex-limited inheritance patterns?
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Study Notes
Inheritance Patterns
- Incomplete Penetrance: A dominant allele is present, but its effects are not seen due to environmental influences or counteracting proteins from other genes.
Incomplete Dominance
- A heterozygote has a phenotype that is intermediate between the two corresponding homozygotes, e.g., a cross between red-flowered and white-flowered parents produces pink-flowered offspring.
Overdominance
- A heterozygote has a trait that is more beneficial than either homozygote.
- Three ways heterozygotes gain benefits:
- Increased resistance to infection by microorganisms
- Producing more forms of protein dimers with enhanced function
- Producing proteins that function under a wider range of conditions
Extensions of Mendelian Inheritance
- Mendelian inheritance describes patterns that obey two laws: the Law of Segregation and the Law of Independent Assortment.
- Simple Mendelian inheritance involves a single gene with two different alleles that display a simple dominant/recessive relationship.
Codominance
- The codominant alleles encode proteins that function slightly differently from each other, and the function of each protein in the heterozygote affects the phenotype uniquely.
- Example: blood typing, where an individual carrying the A and B alleles will have an AB blood type.
X-linked Inheritance
- Inheritance of genes located on the X chromosome.
- In mammals and fruit flies, males have one copy of X-linked genes, whereas females have two copies.
- If a pair of X-linked alleles shows a simple dominant/recessive relationship, 50% of the protein produced by a single copy of the dominant allele in a heterozygous female is sufficient to produce the dominant trait.
Sex-influenced Inheritance
- The effect of sex on the phenotype of an individual.
- Some alleles are recessive in one sex and dominant in the opposite sex.
- Sex hormones may regulate the molecular expression of genes, influencing the phenotypic effects of alleles.
Sex-limited Inheritance
- Traits that occur in only one of the two sexes.
- Example: breast development in mammals.
- Sex hormones that are primarily produced in only one sex are essential to produce a particular phenotype.
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Description
Understanding inheritance patterns, including incomplete penetrance and how environmental influences affect gene expression.