Influenza Viruses: Antigenic Drift and Variation

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18 Questions

Which of the following is responsible for penetration and budding?

Neuraminidase

What is the result of antigenic shift?

Drastic change in the antigenic structure resulting in new H and N antigens

Which of the following is an example of Antigenic drift?

Point mutations in the viral genes encoding the HA and NA spikes

Which of the following is NOT a mechanism of antigenic shift?

Antigenic drift

Which flu is an example of highly pathogenic avian influenza (HPAI)?

H5N1 Avian Flu

What is the result of the reassortment of genomes in antigenic shift?

A new strain of influenza virus

What type of RNA does Orthomyxoviridae have in its genome?

ssRNA

Which of the following is NOT a diagnostic method for Influenza?

Gram Staining

What is the primary function of Neuraminidase Inhibitors in Influenza treatment?

To inhibit the release of viral particles from the host cell

What is the primary goal of Orthomyxoviridae antigenic variation?

To evade the host's immune system

What is the composition of the Influenza A virus?

8 segments of ssRNA

What is the primary method of preventing Influenza?

Vaccination

What is the primary mode of transmission for Retroviridae?

Sexual contact and injection drug use

Which generation of HIV tests detects and differentiates all three HIV analyte markers?

5th generation

What is the result of opportunistic infections in individuals with MOT disease?

All of the above

What is the purpose of ELISA screening in HIV diagnosis?

To screen for HIV infection in high-risk populations

What is the consequence of antigenic variation in HIV?

All of the above

What is the primary goal of pandemic prevention strategies for Retroviridae?

To reduce transmission through sexual contact

This quiz covers the concepts of hemagglutination, neuraminidase, antigenic variation, and antigenic drift in influenza viruses. It explores how mutations in viral genes lead to changes in antigenic structures, resulting in varying effects on the virus.

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