Inflammatory Responses and Wound Healing Basics

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What triggers inflammation?

Infection, tissue damage, or harmful substances

What is the role of mast cells in inflammatory responses?

Release histamine, leading to vasodilation and increased permeability

What happens during the proliferation phase of wound healing?

Fibroblasts produce collagen and angiogenesis occurs

What is chemotaxis in the context of inflammatory responses?

Attraction of immune cells to the site by chemotactic signals

5

Phagocytes engulf and digest pathogens, debris, and damaged cells.

What is the function of cytokines in inflammatory responses?

Coordinate the inflammatory response and attract immune cells.

What occurs during the resolution phase of inflammatory responses?

Anti-inflammatory signals help resolve the inflammatory response once the threat is eliminated.

What stimulates migration of cells involved in tissue repair during wound healing?

Growth factors.

Which cell type is responsible for producing collagen during wound healing?

Fibroblasts.

Which cell type contributes to wound closure through migration and proliferation?

Epithelial cells

What is the main function of myofibroblasts during wound healing?

Assist in wound contraction

Which factor stimulates cell proliferation and tissue repair during wound healing?

Platelet-derived growth factor (PDGF)

What happens during the late phase of wound healing?

Excess cells undergo apoptosis

Which cells clear debris and pathogens during inflammation?

Neutrophils

Learn about the initiation, vasodilation, increased permeability, and chemotaxis in inflammatory responses and wound healing. Understand how the body responds to factors such as infection, tissue damage, or harmful substances.

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