Inflammation & Repair Overview Quiz

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What is the primary function of mast cells in the inflammatory response?

Phagocytosis of pathogens

Release of histamine and increase in vascular permeability (correct)

Recruitment of neutrophils to the site of inflammation

Presentation of antigens to T-cells

Which of the following is a key function of macrophages during inflammation?

Maintaining homeostasis in the body

Releasing cytokines like TNF (correct)

Producing leukotrienes

Presenting antigens to B-cells

What is the primary role of dendritic cells during inflammation?

Recruiting neutrophils to the site of inflammation

Presenting antigens to T-cells (correct)

Phagocytosis of pathogens

Releasing histamine and increasing vascular permeability

What is the term used to describe the process of leukocytes transmigrating through the endothelium into the inflamed tissue?

Diapedesis Signup and view all the answers

Which cell type is responsible for the initial, rapid response to bacterial infection during inflammation?

Neutrophils Signup and view all the answers

What is the primary function of leukotrienes during the inflammatory response?

Recruitment of neutrophils to the site of inflammation Signup and view all the answers

Which of the following cell types is responsible for initiating the acute inflammatory response by releasing histamine?

Mast cells Signup and view all the answers

What is the term used to describe the swelling and fluid accumulation that occurs when lymphatic drainage cannot keep up with increased vascular permeability?

Edema Signup and view all the answers

Which inflammatory mediator is primarily released by mast cells and is associated with allergic responses?

Histamine Signup and view all the answers

Which of the following is a key step in the process of leukocyte recruitment and extravasation during acute inflammation?

Margination and rolling Signup and view all the answers

What is the term used to describe inflammation of the lymphatic vessels?

Lymphangitis Signup and view all the answers

Which of the following cell types is responsible for antigen presentation and activation of the adaptive immune response during acute inflammation?

Dendritic cells Signup and view all the answers

What is the process by which leukocytes migrate through the vessel wall during inflammation?

Diapedesis Signup and view all the answers

What is the primary function of opsonins during the inflammatory response?

To enhance the binding and breakdown of microbes by macrophages Signup and view all the answers

Which of the following is NOT a consequence of persistent infections or ischemia-reperfusion injuries?

Increased production of reactive oxygen species Signup and view all the answers

What is the primary role of neutrophils during the acute inflammatory response?

To phagocytose and kill pathogens Signup and view all the answers

Which type of immune cell is responsible for the 'cavalry charge' of leukocytes during the acute inflammatory response?

Neutrophils Signup and view all the answers

What is the primary mechanism by which leukocytes become activated during the inflammatory response?

All of the above Signup and view all the answers