Inflammation Mediators Quiz
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Questions and Answers

Which cell types produce mediators of acute inflammation?

  • Tissue macrophages, dendritic cells, and mast cells (correct)
  • Neutrophils, endothelial cells, and platelets
  • Tissue macrophages, B cells, and natural killer cells
  • Eosinophils, basophils, and T cells

Where are plasma-derived mediators mainly produced?

  • Lungs
  • Liver (correct)
  • Bone marrow
  • Spleen

Which type of mediators are stored as preformed molecules in cells?

  • Leukotrienes
  • Cytokines
  • Vasoactive Amines (correct)
  • Prostaglandins

What must happen for plasma-derived mediators to become active?

<p>They must be activated by a series of proteolytic cleavages (C)</p> Signup and view all the answers

Which cells are for a lesser extent involved in producing mediators of acute inflammation?

<p>Most epithelia (D)</p> Signup and view all the answers

Flashcards

Mediators of Acute Inflammation

Substances that facilitate the inflammatory response, produced by certain cells.

Sources of Plasma-Derived Mediators

Plasma-derived mediators are mainly produced in the liver.

Preformed Molecules in Cells

Vasoactive Amines are stored as preformed molecules in certain cells.

Activation of Plasma-Derived Mediators

To become active, plasma-derived mediators need proteolytic cleavages.

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Epithelial Cells in Inflammation

Most epithelia play a lesser role in producing mediators of inflammation.

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Study Notes

Cells Producing Mediators of Acute Inflammation

  • Leukocytes (neutrophils, macrophages, and mast cells) and endothelial cells produce mediators of acute inflammation.

Production of Plasma-Derived Mediators

  • Plasma-derived mediators are mainly produced in the liver.

Preformed Mediators

  • Histamine and serotonin are stored as preformed molecules in cells.

Activation of Plasma-Derived Mediators

  • Plasma-derived mediators must be activated by enzymes to become active.

Other Cells Involved in Mediator Production

  • Platelets and epithelial cells are involved in producing mediators of acute inflammation to a lesser extent.

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Description

Test your knowledge of cell-derived mediators involved in inflammation with this quiz. Explore the types of mediators released by cells in response to stimuli and enhance your understanding of the role they play in acute inflammation.

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