Podcast
Questions and Answers
Which cell types produce mediators of acute inflammation?
Which cell types produce mediators of acute inflammation?
- Tissue macrophages, dendritic cells, and mast cells (correct)
- Neutrophils, endothelial cells, and platelets
- Tissue macrophages, B cells, and natural killer cells
- Eosinophils, basophils, and T cells
Where are plasma-derived mediators mainly produced?
Where are plasma-derived mediators mainly produced?
- Lungs
- Liver (correct)
- Bone marrow
- Spleen
Which type of mediators are stored as preformed molecules in cells?
Which type of mediators are stored as preformed molecules in cells?
- Leukotrienes
- Cytokines
- Vasoactive Amines (correct)
- Prostaglandins
What must happen for plasma-derived mediators to become active?
What must happen for plasma-derived mediators to become active?
Which cells are for a lesser extent involved in producing mediators of acute inflammation?
Which cells are for a lesser extent involved in producing mediators of acute inflammation?
Flashcards
Mediators of Acute Inflammation
Mediators of Acute Inflammation
Substances that facilitate the inflammatory response, produced by certain cells.
Sources of Plasma-Derived Mediators
Sources of Plasma-Derived Mediators
Plasma-derived mediators are mainly produced in the liver.
Preformed Molecules in Cells
Preformed Molecules in Cells
Vasoactive Amines are stored as preformed molecules in certain cells.
Activation of Plasma-Derived Mediators
Activation of Plasma-Derived Mediators
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Epithelial Cells in Inflammation
Epithelial Cells in Inflammation
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Study Notes
Cells Producing Mediators of Acute Inflammation
- Leukocytes (neutrophils, macrophages, and mast cells) and endothelial cells produce mediators of acute inflammation.
Production of Plasma-Derived Mediators
- Plasma-derived mediators are mainly produced in the liver.
Preformed Mediators
- Histamine and serotonin are stored as preformed molecules in cells.
Activation of Plasma-Derived Mediators
- Plasma-derived mediators must be activated by enzymes to become active.
Other Cells Involved in Mediator Production
- Platelets and epithelial cells are involved in producing mediators of acute inflammation to a lesser extent.
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